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Marlins vs. Dodgers Prediction, MLB Picks for Wednesday, April 29

Los Angeles Dodgers DH Shohei Ohtani celebrates against the New York Mets.
AP Photo/Jayne Kamin-Oncea

Marlins vs. Dodgers is set for first pitch at 3:10 p.m. ET on Wednesday, April 29, with the Dodgers returning a 1.4x payout if they win, via PrizePicks.

We have the potential for an excellent pitching matchup with Marlins SP Sandy Alcantara (3-2, 3.05 ERA) facing Dodgers SP Tyler Glasnow (3-0, 2.45 ERA).

Below, we’ll break down our Marlins vs. Dodgers prediction and picks for Wednesday’s MLB game, including the game winner, over/under, and key player picks for PrizePicks.

Make your picks for Marlins vs. Dodgers on PrizePicks now.

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Marlins vs. Dodgers Prediction, Winner Payout, Over/Under – Wednesday, April 29

The Marlins earned a 2-1 win over the Dodgers on Tuesday. Dodgers SP/DH Shohei was the starter for the game and the team decided not to have him hit, which contributed to its inability to score runs.

For the season, though, L.A. has scored the second-most runs (165) in baseball.

The Marlins have been middle-of-the-pack on offense, ranking 16th in runs scored (132). They only have a .712 OPS, compared to a .807 mark for the Dodgers.

Marlins vs. Dodgers Winner Payout, Over/Under – Wednesday, April 29

The Dodgers enter Wednesday’s game as a home favorite against the Marlins, returning a 1.4x payout if they win outright, via PrizePicks Team Picks.

Here are the full payouts for the Marlins vs. Dodgers game on PrizePicks.

  • Spread: Los Angeles Dodgers -1.5 (1.88x payout)
  • Over/Under: 8.5 runs (1.96x payout on Over)
  • Gamer Winner Payout: Dodgers 1.4x | Marlins 2.77x

Play the Marlins vs. Dodgers winner or over/under on PrizePicks Team Picks to earn real money — available in 35 states!

Team Picks data is live as of writing and is subject to change.


Marlins vs. Dodgers Prediction on Winner – 4/29/26

Here are the key game stats and trends behind our Marlins vs. Dodgers prediction on the winner for Wednesday, April 29.

Lock in your Marlins vs. Dodgers prediction on PrizePicks before the line moves.

  • Despite the loss Tuesday, the Dodgers are 20-10 this season. That includes them going 12-5 at home.
  • The Marlins are 10-6 at home but just 4-10 on the road.
  • The Dodgers have a +67 run differential, the second-best mark in the majors. The Marlins have a neutral 0 run differential.
  • Los Angeles has won all five games that Glasnow has started in 2026.
  • According to FanGraphs, the Dodgers have the second-best barrel rate (11.3%) in the bigs. Meanwhile, the Marlins have the third-lowest mark (6.4%).

Marlins vs. Dodgers Player Picks, Stats for PrizePicks: 4/29/26

Here are the top Marlins vs. Dodgers picks to target on PrizePicks for Wednesday, April 29. Today's MLB picks for PrizePicks include DH Shohei Ohtani and OF Jakob Marsee.

Dodgers DH Shohei Ohtani vs. Marlins Projection: 1.5 Total Bases

  • Prior to being out of the lineup Tuesday, Ohtani had produced back-to-back games with 3 hits.
  • Over his last 11 games, the two-way star is 14-for-45 (.311) with 1 home run and 5 doubles.
  • Ohtani has 30 hits this season, 12 of which have gone for extra bases.
  • The two-time World Series champion had a .416 wOBA and a .333 ISO at home last year.
  • Alcantara is not overpowering, owning a 16.3% strikeout rate this season and a 20.9% K-rate for his career.
  • The Marlins' ace had a 4.70 xFIP and a 1.55 WHIP on the road in 2025, compared to a 3.88 xFIP and a 1.10 WHIP at home.

Add Shohei Ohtani to your PrizePicks Lineup now.

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Marlins OF Jakob Marsee vs. Dodgers Projection: 5.5 Hitter Fantasy Score

  • Marsee went 0-for-4 with 4 strikeouts in Tuesday’s victory.
  • The 25-year-old is off to a disappointing start, batting just .184 with a .273 wOBA.
  • Marsee’s quality of contact has contributed to his struggles. He only has a 2.4% barrel rate and a 38.8% hard-hit rate.
  • Glasnow has allowed all of 16 hits across 33 innings. Over 787 career innings, he's given up just 591 hits.
  • Since joining the Dodgers, the right-handed star has a 2.85 xFIP and a 0.82 WHIP at home. Opponents are hitting .187 against him in Los Angeles.
  • According to Baseball Savant, Marsee is batting .167 against fastballs. He only hit .247 against them last year. Opponents hit .207 versus Glasnow’s heater last year.

Add Jakob Marsee to your PrizePicks Lineup now.


Make Marlins vs. Dodgers Picks on PrizePicks

The Dodgers look to get back in the win column in a home game against the Marlins on Wednesday. Ohtani could continue to rack up extra-base hits at home, while a matchup against Glasnow isn't ideal for Marsee to break out of his slump.

Don’t wait until the first pitch — make your Marlins vs. Dodgers picks on PrizePicks now and earn real money if you’re right.

Pick players, predict More or Less on their stats, and cash in if you’re right. With Team Picks, you can make predictions on game winners, spreads, and over/unders, now available in 35 states.

Stay locked in on Playbook for daily MLB predictions, picks, and news every day all the way through the 2026 MLB season.

Get in the game! Sign up for PrizePicks and cash in on your sports predictions. Play $5 and get $50 instantly in Lineups with promo code PLAYBOOK.

Team Picks and Culture Picks are event contracts offered by Performance Predictions II, LLC d/b/a PrizePicks Predict, a CFTC-registered FCM and NFA Member. All event contract customers must be U.S. residents and 18+. Some event contracts may not be available in every state. Event contract trading carries significant risk and is not appropriate for everyone. No guarantee against loss is offered. Past results are not necessarily indicative of future results. Void where prohibited by law. Restrictions apply. For full terms of service see prizepicks.com/predict-regulatory. Team and Culture Pick Early Payouts subject to market liquidity. The content provided is for informational and educational purposes only and does not constitute investment advice, or a recommendation to trade any commodity interest.

about the author

Mike Barner has been covering fantasy sports since 2007. He specializes in the NBA, NFL, and MLB. He is a two-time finalist for the Fantasy Sports Writers Association Basketball Writer of the Year award and won the 2021-22 FSGA NBA Experts Champions league. In addition to PrizePicks, Mike has written for Sports Illustrated, RotoWire, SportsLine, and more.

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