Tuesday’s UEFA Nations League match between England and Czechia kicks off at 2:45 p.m. ET. England enters the Nations League match as significant favorites on their home pitch, returning a 1.08x payout to win on PrizePicks.
England wraps up a mostly successful international break with a second and final leg against Czechia. The 2026 World Cup third-place side has won back-to-back games coming into Tuesday’s match, including a historic 7-0 win over Croatia on Saturday.
Below, we'll break down our England vs. Czechia prediction and picks for Tuesday's UEFA Nations League match, including winner payouts and player picks for PrizePicks.
Make your England vs. Czechia prediction on PrizePicks now!
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England vs. Czechia Prediction, Picks for UEFA Nations League Match – Tuesday, October 6
How to watch England vs. Czechia: FOX One
Kickoff Time: 2:45 p.m. ET
Venue: Wembley Stadium, London, England
England opened Nations League play with a 3-2 defeat to the reigning world champions, Spain. Since then, the Three Lions have bounced back with back-to-back impressive wins, including a 2-0 victory over Czechia last Tuesday afternoon. The two sides now meet again in the group stage before the club season resumes this weekend.
Czechia has now lost all three of their Nations League matches, scoring just 2 goals across those games. Santi Denia's squad has conceded 7 goals during the international break and has picked up a red card in back-to-back games heading into Tuesday's matchup.
England's all-time leading scorer ST Harry Kane netted twice on Saturday and has scored 4 goals across the three games of this international break. He and LW Anthony Gordon have scored in all three Nations League matches and were the only scorers when these sides met last Tuesday.
Thomas Tuchel's squad leads all teams in the UEFA Nations League with 11 goals scored and could make it three straight clean sheets as heavy favorites against a Czechia side that has struggled throughout the break.
England vs. Czechia Winner Payouts for UEFA Nations League – Tuesday, October 6
England enters Tuesday’s game as home favorites against Czechia, returning a 1.08x payout if they win outright, via PrizePicks.
Meanwhile, Czechia will look to pull off a massive upset as road underdogs, with their 16.66x payout to win. PrizePicks has an 8.33x payout for a draw today.
Here are the full payouts for the England vs. Czechia game on PrizePicks.
Make your England vs. Czechia prediction on the winner on PrizePicks.
PrizePicks data is live at the time of writing and is subject to change.
England vs. Czechia Prediction on Winner for UEFA Nations League – 10/6/26
Here are the key game stats and trends behind our England vs. Czechia prediction on the winner for the Nations League match on Tuesday, October 6.
- England's 11 goals across three Nations League matches lead all participants. The Three Lions have also created a competition-high 18 big chances.
- Czechia's 1.73 xG ranks 49th of the 54 teams in the competition, with their 5.3 total shots per game ranking 53rd.
- England ranks fourth in the Nations League, averaging 7.3 shots on target per game. Their 9.65 xG is second behind the Netherlands.
- Czechia has created just 3 big chances across their three matches, including only 1 in the home leg against England, finishing that game with just 0.32 xG.
- England took a team-high 22 total shots in last Tuesday's meeting with Czechia, but only 7 were on target. It was the Three Lions' lowest xG output (1.48) of the three games played.
Lock in your England vs. Czechia prediction on PrizePicks before kick-off.
England vs. Czechia Projected Lineups – Tuesday, October 6
Take a look at the England vs. Czechia projected lineups for today's UEFA Nations League match. Lineups are not official and should be confirmed before match start.
England Lineup vs. Czechia: Projected 4-2-3-1
Goalkeeper: Jordan Pickford
Defense: Jarell Quansah, Jarrad Branthwaite, Marc Guéhi, Lewis Hall
Midfield: Elliot Anderson, Myles Lewis-Skelly, Jude Bellingham
Forwards: Bukayo Saka, Anthony Gordon, Harry Kane
Czechia Lineup vs. England: Projected 4-2-3-1
Goalkeeper: Antonín Kinský
Defense: Jiří Sláma, Martin Vitík, Štěpán Chaloupek, Michael Šáček
Midfield: Alex Král, Pavel Šulc, Lukáš Ambroš
Forwards: Ondřej Lingr, Adam Hložek, Pavel Bucha
England vs. Czechia Picks, Player Stats for PrizePicks: 10/6/26
Here are England vs. Czechia picks to target for the UEFA Nations League on Tuesday, October 6. Today’s Nations League picks include Jude Bellingham and Antonín Kinský.
England MF Jude Bellingham vs. Czechia: 3 Shots
- Bellingham scored his first goal of the international break in Saturday's win and ranks fourth on the squad with 2.3 total shots per game.
- He has largely served as England's primary playmaker in the Nations League so far, contributing 4 assists in three games and averaging 4.3 key passes per contest.
- Of England's 22 total shots in the first leg against Czechia, Bellingham took only 2 — coming on as a substitute in the 71st minute rather than starting. He has not surpassed 3 shots in a game even when starting.
Add Jude Bellingham to your PrizePicks lineup now!
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Czechia GK Antonín Kinský vs. England: 5 Goalie Saves
- The young Tottenham goalkeeper was handed his first senior international appearance against Spain on Saturday, finishing with 7 saves despite a 3-1 defeat.
- Kinský is in for another demanding afternoon, given Czechia's defensive numbers throughout the break. The Czechs are conceding 7.33 shots on target per game and faced 10 on target in the 23-year-old's first start.
- Goalkeepers facing England are averaging 3.33 saves against the Three Lions across the first three Nations League matches.
Add Antonín Kinský to your PrizePicks lineup now!
Make England vs. Czechia Picks on PrizePicks
England will look to close out the international break with a third straight UEFA Nations League win when they host Czechia on Tuesday, October 6, at 2:45 p.m. ET. Czechia, still searching for their first point of the competition, hopes to avoid a second defeat to the Three Lions within a week.
Don’t wait until kickoff — make your England vs. Czechia picks for Tuesday’s UEFA Nations League match now on PrizePicks to earn real money if you're right.
Just pick your UEFA Nations League players, predict More or Less on their stats, and cash in if you’re right. With Team Picks, you can make predictions on match winner, total goals, and both teams to score — now available in 36 states.
Stay locked in with the Playbook for continued soccer and UEFA Nations League predictions, picks, and analysis.
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