The Chicago Cubs vs. Los Angeles Dodgers game is set for first pitch at 10:15 p.m. ET on Friday, April 24, with Los Angeles returning a 1.56x payout to win the clash on Apple TV, via PrizePicks.
Both these National League clubs are tied for first place in their respective divisions heading into this critical series at Dodger Stadium. The Cubs seek their 10th consecutive victory, while the Dodgers return home after dropping two of three at San Francisco.
Below, we'll break down our Cubs vs. Dodgers prediction and picks for Friday's MLB game, including the winner, over/under, and key player picks for PrizePicks.
Make your picks for Cubs vs. Dodgers on PrizePicks now.
{{mlb_offer_banner="/style-system/ui-components-playbook"}}
Cubs vs. Dodgers Prediction, Winner Payout, Over/Under – Friday, April 24
The Cubs (16-9) sat below the .500 mark on April 13 after falling to the Philadelphia Phillies, 13-7. Chicago now heads to Southern California coming off a four-game home sweep of those same Phillies.
In seven of nine games during this hot streak, the Cubs topped the 5-run mark while posting three straight outings of double-digit runs from April 14-17.
The Dodgers (17-8) and San Diego Padres are tied for first place in the NL West after both teams won on Thursday. Los Angeles dropped the first two games at the San Francisco Giants, but the Dodgers blanked the Giants 3-0 in the finale.
Los Angeles captured the first three matchups last season, including a pair of victories in Tokyo. The Cubs won the final four meetings, highlighted by a 16-0 blowout at Chavez Ravine.
Cubs vs. Dodgers Winner Payout, Over/Under – Friday, April 24
The Dodgers enter Friday’s game as home favorites against the Cubs, returning a 1.56x payout if they win outright, via PrizePicks Team Picks.
Here are the full payouts for the Cubs vs. Dodgers game on PrizePicks.
- Spread: Los Angeles Dodgers -1.5
- Over/Under: 9.0
- Game Winner Payout: Cubs 2.32x | Dodgers 1.56x
Play the Cubs vs. Dodgers winner or over/under on PrizePicks Team Picks to earn real money — available in 35 states!
Team Picks data is live at the time of writing and is subject to change.
Cubs vs. Dodgers Prediction on Over/Under – 4/24/26
Here are the key game stats and trends behind our Cubs vs. Dodgers prediction on the over/under for Friday, April 24.
Lock in your Cubs vs. Dodgers prediction on PrizePicks before the line moves.
- These teams rank in the top three in wOBA, with the Dodgers leading the way at .365. The Cubs sit third at .351 and own a .345 wOBA on the road.
- The Cubs are 6-1 to the over in the last seven away games, while averaging 7.42 runs per outing.
- SP Jameson Taillon has been up and down this season, allowing 1 or fewer runs in two starts but 10 runs in his other two outings.
- The Dodgers are coming off their worst offensive series, scoring 4 runs against the Giants in three games.
- Chicago’s pitching staff is allowing an average exit velocity of 90.1, tied for third-worst in MLB.
Cubs vs. Dodgers Player Picks, Stats for PrizePicks: 4/24/26
Here are top Cubs vs. Dodgers picks to target on PrizePicks for Friday, April 24. Today’s MLB picks for PrizePicks include SP Emmet Sheehan and LF Ian Happ.
Dodgers SP Emmet Sheehan vs. Cubs Projection: 5 Strikeouts
- Sheehan’s strikeout rate has dropped from 30.6% in 2025 to 20.9% through four starts.
- The right-hander posted 6 Ks in each of his two home outings against the Diamondbacks and Rangers.
- The Cubs are tied for 25th in strikeout rate at 20.7%, striking out fewer than five times against opposing starters in seven of the last eight games.
- Last season, Sheehan owned a 23.7% K rate on four-seam fastballs, but that number is just 13% in 2026.
Add Emmet Sheehan to your PrizePicks Lineup now.
{{mlb_offer_banner="/style-system/ui-components-playbook"}}
Cubs LF Ian Happ vs. Dodgers Projection: 5.5 Hitter Fantasy Score
- Happ posted 21 fantasy points in Thursday’s walk-off win over the Phillies, extending his hitting streak to seven games with a pair of hits.
- The 31-year-old hit .333 against the Dodgers last season but only drove in 2 runs in 30 at-bats.
- Happ has eclipsed this fantasy projection in five consecutive games, averaging 12.2 points in this stretch.
- The left fielder has a hard-hit rate of 83.3% against four-seam fastballs, along with a slugging percentage of .583.
Add Ian Happ to your PrizePicks Lineup now.
Make Cubs vs. Dodgers Picks on PrizePicks
The Cubs are the hottest team in baseball and will be tested against the defending champion Dodgers this weekend. Can Los Angeles get its offense on track back at home?
Don’t wait until lock — make your Cubs vs. Dodgers picks on PrizePicks now and earn real money if you’re right.
Pick players, predict More or Less on their stats, and cash in if you’re right. With Team Picks, you can make predictions on game winners, spreads, and over/unders, now available in 35 states.
Stay locked in on Playbook for daily MLB predictions, picks, and news every day all the way through the 2026 World Series.
