Although the Week 3 college football slate isn't exactly stacked today, one of the most coveted games of the season headlines the schedule. LSU head coach Lane Kiffin returns to his old stomping grounds in Oxford, Miss., to take on Ole Miss in a battle of top-10-ranked teams.
Before all attention turns to the #7 LSU vs. #8 Ole Miss showdown at 7:30 p.m. ET on ABC, there's plenty of top teams in action, including #2 Georgia starting conference play vs. Arkansas at 12 p.m. ET, and #16 SMU vs. #23 Louisville at 3:30 p.m. ET on ESPN2.
Below is the full Week 3 college football schedule for Saturday’s games, the TV channel for every key NCAAF game, and current spreads via PrizePicks Team Picks — now available in 35 states!
You can make picks on NCAAF winners, spreads, totals, and more in eligible states, and add Player Picks to the same lineup for even bigger payouts all season long!
Make your Week 2 college football picks on PrizePicks — including winners, spreads, and over/unders!
{{cfb_offer_banner="/style-system/ui-components-playbook"}}
College Football Games Today: Week 3 Schedule, TV Channels, & Spreads
All game times are in Eastern Time. Spreads and winner payouts are live on PrizePicks Team Picks as of posting, but are subject to change.
The schedule below encompasses all top 25 teams and the best college football games to watch today. Times and TV channels are via ESPN. Games on streaming only, such as ESPN+, are excluded.
Payouts below, like 3x, represent real-money multipliers on correct picks on PrizePicks Team Picks at the time of writing. For example, a $100 entry on Ole Miss to win at a 2.22x multiplier would pay out $222 if you're right.
See live payouts and spreads in the PrizePicks app — new users get $150 if you win your first $5 lineup with code PLAYBOOK!
{{cfb_offer_banner="/style-system/ui-components-playbook"}}
How to Watch College Football Games Today – Saturday, September 19
Today's NCAAF slate runs 11 hours on paper — from the 12:00 p.m. ET openers through a trio of West Coast late-nighters at 11:00 p.m. ET that'll push into the early hours of Sunday. The 22 games above are listed across 12 TV networks, including one transatlantic kickoff: Arizona and Kansas open the day from Wembley Stadium in London.
Starting the day in the noon window, #2 Georgia is a massive favorite over Arkansas on ABC, while Buffalo heads to Happy Valley to face #14 Penn State on BTN. Overseas, Arizona State vs. Kansas kicks off from Wembley Stadium in London at 12 p.m. ET on FS1. Back stateside, UNC hosts Clemson on ESPN/Disney+, and the window closes at 12:45 p.m. ET with NC State vs. Vanderbilt on SEC Network.
The afternoon window — starting at 3:30 p.m. ET — is stacked with ranked matchups. Kentucky visits #9 Texas A&M on ESPN, Florida State travels to #10 Alabama on ABC, and #12 USC hosts Rutgers on CBS.
The headliner of the window is the day's tightest ranked-vs-ranked clash: #16 SMU at #23 Louisville on ESPN2. Elsewhere, Utah State visits #17 Utah on FOX, UTEP heads to Ann Arbor for #19 Michigan on BTN, Northern Iowa is at #18 Iowa on FS1 (4:00 p.m. ET), and Mississippi State vs. South Carolina wraps the window at 4:15 p.m. ET on SEC Network.
The night slate opens early with Florida at Auburn (7:00 p.m. ET, ESPN), then the marquee matchup of the evening kicks off at 7:30 p.m. ET: #7 LSU at #8 Ole Miss on ABC, the day's best ranked-vs-ranked showdown, with all eyes on Lane Kiffin and the Tigers in a hostile environment.
The night window is loaded with games worth keeping tabs on if you're multi-tasking with several TVs — Michigan State at #3 Notre Dame on NBC, #11 BYU hosting Colorado State on CBS, New Mexico at #24 Oklahoma on ESPN2, and West Virginia at #25 Virginia on ACCN.
There's plenty in the late-night window too — for the real sickos. Three West Coast kickoffs close the book on Week 3 at 11:00 p.m. ET: Purdue at UCLA (BTN), Montana at Oregon State (USA Network), and Fresno State at San José State (FS1).
Make your college football picks on winners and spreads on PrizePicks now!
{{cfb_offer_banner="/style-system/ui-components-playbook"}}
Must-Watch NCAAF Games Today – Saturday, September 19
Here are the games you should slot into the quad-box for Week 3 during each window today.
Best NCAAF Noon Games Today
- #2 Georgia vs. Arkansas – ABC
- Buffalo vs. #14 Penn State – BTN
- Arizona State vs. Kansas (Wembley, London) – FS1
- UNC vs. Clemson – ESPN/Disney+
Best NCAAF Afternoon Games Today
- Kentucky vs. #9 Texas A&M – ESPN
- Florida State vs. #10 Alabama – ABC
- #12 USC vs. Rutgers – CBS
- #16 SMU vs. #23 Louisville – ESPN2
Best NCAAF Night Games Today
- #7 LSU vs. #8 Ole Miss – ABC
- Michigan State vs. #3 Notre Dame – NBC
- #11 BYU vs. Colorado State – CBS
- Florida vs. Auburn – ESPN
Best NCAAF Late Night Games Today
- Purdue vs. UCLA – BTN (11:00 p.m. ET)
- Montana vs. Oregon State – USA Network (11:00 p.m. ET)
- Fresno State vs. San José State – FS1 (11:00 p.m. ET)
Week 3 NCAAF Spreads, Winners, Payouts Today on PrizePicks
The tightest spread on the PrizePicks board belongs to a ranked-vs-ranked showdown: #16 SMU is only a 1.5-point underdog against #23 Louisville, making it the closest thing to a true toss-up on today's slate among top teams.
Beyond that, single-possession games are scattered throughout the day, including #7 LSU-#8 Ole Miss (3), NC State-Vanderbilt (3.5), Mississippi State-South Carolina (3.5), UNC-Clemson (3.5), and Florida-Auburn (2.5).
But the broader trend today is lopsided, as tends to be the case when ranked teams host outmatched non-conference or rebuilding opponents. Several ranked teams are set as 20+-point favorites, with Buffalo at #14 Penn State (39.5), Northern Iowa at #18 Iowa (38.5), UTEP at #19 Michigan (35.5), #2 Georgia over Arkansas (24.5), and #12 USC over Rutgers (21.5) among the widest gaps on the board.
The rest of Week 3 is on the PrizePicks board now, with picks available for every game. In eligible states, you can make picks on college football winners, spreads, and totals. Then add Player Picks to the same lineup for bigger potential payouts.
For the first time ever, you can pick CFB winners on PrizePicks — now's the time to make your move.
Make your College Football picks now on PrizePicks!
{{cfb_offer_banner="/style-system/ui-components-playbook"}}
PrizePicks Promo Code for College Football: PLAYBOOK – Play $5, Get $150
New to PrizePicks? It's time to lock your college football picks in — from winners to player picks. Use promo code PLAYBOOK when you sign up. Win your first eligible $5+ lineup, and you'll get $150 in Bonus Lineups.
You must use official PrizePicks promo code PLAYBOOK to claim this new user offer, and a $10 minimum first deposit is required to get started.
After a qualifying win, claim the Welcome Bonus Mission in the Rewards tab within seven days, then use your Bonus Lineups within the following seven days — all in the app!
Use promo code PLAYBOOK: Play $5, get $150 if you win! Sign up and make your first college football picks today!
{{cfb_offer_banner="/style-system/ui-components-playbook"}}
Make Saturday College Football Picks & Predictions on PrizePicks
Although we have a relatively underwhelming slate of games today, we get two matchups that pit top-25 teams against one another, including LSU vs. Ole Miss, as Lane Kiffin returns to his old school after leaving them before last year's College Football Playoff.
Need some expert CFB picks and predictions before you lock in your college football lineup today? Tap into the Playbook’s Week 3 CFB research from our experts for coverage on the top games.
Stay locked in on the Playbook college football home for daily picks, predictions, spreads, and game previews throughout the 2026 college football season.
Team Picks and Culture Picks are event contracts offered by Performance Predictions II, LLC d/b/a PrizePicks Predict, a CFTC-registered FCM and NFA Member. All event contract customers must be U.S. residents and 18+. Some event contracts may not be available in every state.Event contract trading carries significant risk and is not appropriate for everyone. No guarantee against loss is offered. Past results are not necessarily indicative of future results.Void where prohibited by law. Restrictions apply. For full terms of service see prizepicks.com/predict-regulatory. Team and Culture Pick Early Payouts subject to market liquidity. The content provided is for informational and educational purposes only and does not constitute investment advice, or a recommendation to trade any commodity interest.
