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Brighton vs. Chelsea Prediction, XIs, Picks for EPL on Tuesday, April 21

Chelsea's Alejandro Garnacho leaves the pitch after a game against Hull City.
AP Photo/Jon Super

After both teams played on Saturday, it's a quick turnaround when Brighton hosts Chelsea in a Premier League matchup on Tuesday, April 21 at 3:00 p.m. ET on USA Network.

According to PrizePicks Team Picks, Brighton is slightly favored at home, returning a 2.32x payout if they secure a victory.

Below, we’ll discuss our Brighton vs. Chelsea Premier League prediction and picks for Tuesday’s match.

Make your picks for Brighton vs. Chelsea on PrizePicks now.

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Brighton vs. Chelsea Prediction, Spread, Total Goals for Premier League – Tuesday, April 21

On Saturday, Brighton secured a draw on the road against Tottenham, putting them in the No. 9 spot in the Premier League standings. With five games remaining, Brighton is just two points ahead of No. 12 Fulham, so they’ll aim to finish strong and stay in the top half of the table.

There’s still an outside chance Brighton can climb inside the top six. They possess a 3.22x payout to achieve the No. 6 spot or higher via PrizePicks Team Picks.

As for Chelsea, they were defeated 1-0 at home by Man United on Saturday. Chelsea didn’t make any movement at No. 6 in the Premier League table following the loss, though Brentford and Bournemouth also have 48 points.

Upon getting eliminated by PSG in this year’s UEFA Champions League Tournament, Chelsea might need to get inside the top five in the EPL standings to qualify for next year.

Entering the final stretch of the campaign, Chelsea has a 2.43x payout to finish in the top six in the EPL, per PrizePicks Team Picks.


Brighton vs. Chelsea Spread, Total Goals, Payouts – 4/21/26

Brighton enters Tuesday’s match as home favorites, returning a 2.32x payout ($100 entry pays out $232) on PrizePicks Team Picks if they win outright.

Here are the full payouts for the Brighton vs. Chelsea game on PrizePicks.

  • Winner Payout: Chelsea – 2.56x | Tie – 3.44x | Brighton – 2.32x
  • Spread: Brighton -1.5 (4.34x payout)
  • Total Goals: 3.5 (Over – 1.61x)
  • Both Teams to Score: Yes 1.51x | No 2.38x

Play the Brighton vs. Chelsea spread or total goals on PrizePicks Team Picks to earn real money — available in 35 states!

Team Picks data is live at the time of writing and is subject to change. Does not include extra time or penalties.


Brighton vs. Chelsea Prediction on Total Goals – 4/21/26

Here are some stats to know to help you make your Brighton vs. Chelsea prediction on total goals for Tuesday, April 21. Check out more of our soccer picks and predictions on Playbook.

Lock in your Brighton vs. Chelsea prediction on PrizePicks before the line moves.

  • Brighton has had 3 or more total goals scored in two of their last three home matches and two of their last three matches overall in the Premier League.
  • Across their first 16 away matches in the EPL, Chelsea has seen at least 3 total goals scored in 12 of them.
  • Furthermore, there have been 3 or more total goals scored in eight of the last 11 EPL games involving Chelsea. They’ve allowed their opponent to score at least once in all 11 of those matches.
  • When these teams met early in the season, Brighton secured a 3-1 victory as the visiting club.
  • According to FotMob, Chelsea is first in xG (62.0), while Brighton is ninth in xG (48.8).
  • Chelsea has the fifth-most shots on target per match (4.6), and Brighton has the ninth-most (4.5).
  • Both these teams excel at pushing the ball forward and getting the ball in scoring position, as Brighton is fourth in touches in the opposition’s box (908). Chelsea is fifth (905).

Brighton vs. Chelsea Projected Lineups for Tuesday, April 21

Here are the projected Brighton vs. Chelsea lineups for today's Premier League match. Lineups are not official.

Brighton Lineup vs. Chelsea: Projected 4-3-3

  • Goalkeeper: Bart Verbruggen
  • Defense: Ferdi Kadioglu, Lewis Dunk, Jan Paul van Hecke, Mats Wieffer
  • Midfield: Pascal Gross, Carlos Baleba, Jack Hinshelwood
  • Forwards: Kaoru Mitoma, Danny Welbeck, Yankuba Minteh

Chelsea Lineup vs. Brighton: Projected 4-2-3-1

  • Goalkeeper: Robert Sanchez
  • Defense: Marc Cucurella, Jorrel Hato, Wesley Fofana, Malo Gusto
  • Midfield: Moises Caicedo, Enzo Fernandez, Cole Palmer
  • Forwards: Pedro Neto, Joao Pedro, Alejandro Garnacho

Brighton vs. Chelsea Player Picks, Stats for PrizePicks: 4/21/26

Here are two Brighton vs. Chelsea projections to target on players for Tuesday, April 21. Player picks via PrizePicks are headlined by Bart Verbruggen and Joao Pedro.

Brighton GK Bart Verbruggen vs. Chelsea

Bart Verbruggen Projections via PrizePicks: 3 Goalie Saves, 39.5 Passes Attempted

  • Bart Verbruggen has made at least 3 saves in eight of his last 10 EPL matches.
  • Plus, Verbruggen has tallied 3 or more saves in four of his last six home starts.
  • Brighton tends to play passes back to Verbruggen in goal, as he’s logged 40 or more passes in 13 of his last 14 matches in the Premier League.

Add Bart Verbruggen to your PrizePicks Lineup now.

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Chelsea F Joao Pedro vs. Brighton

Joao Pedro Projections via PrizePicks: 1.5 Shots (Goblin), 0.5 Shots on Target (Goblin), 0.5 Goals (Demon)

  • Besides Joao Pedro facing his former club, he has delivered 3 or more shots in six of his last seven EPL contests.
  • During that same seven-game span, Pedro has tallied at least 1 shot on target in five of those matches.
  • Pedro leads Chelsea in scoring against Premier League opponents, scoring 14 goals this season.
  • On top of that, Pedro is second on Chelsea in xG per 90 minutes (0.51).

Add Joao Pedro to your PrizePicks Lineup now.


Make Brighton vs. Chelsea Picks on PrizePicks

Brighton are looking to remain in the top half of the Premier League table at season’s end, while Chelsea would love to ensure they are playing Champions League soccer again next year. Will one of them secure a valuable win on Tuesday?

You can make your Brighton vs. Chelsea picks on PrizePicks and PrizePicks Team Picks to earn real money on Premier League games. Just pick players, predict More or Less on their projected stats like shots or goals, and cash in if you’re correct. 

With Team Picks, make predictions on winners, spreads, and over/unders, now available in 35 states

Stick around with the Playbook for continued Premier League predictions, picks, and analysis through the end of the season.

Get in the game! Sign up for PrizePicks and cash in on your sports predictions. Play $5 and get $50 instantly in Lineups with promo code PLAYBOOK.

Team Picks and Culture Picks are event contracts offered by Performance Predictions II, LLC d/b/a PrizePicks Predict, a CFTC-registered FCM and NFA Member. All event contract customers must be U.S. residents and 18+. Some event contracts may not be available in every state. Event contract trading carries significant risk and is not appropriate for everyone. No guarantee against loss is offered. Past results are not necessarily indicative of future results. Void where prohibited by law. Restrictions apply. For full terms of service see prizepicks.com/predict-regulatory. Team and Culture Pick Early Payouts subject to market liquidity. The content provided is for informational and educational purposes only and does not constitute investment advice, or a recommendation to trade any commodity interest.

about the author

Skyler Carlin is an experienced writer with nearly 10 years of experience writing and editing NFL, NBA, MLB, CFB, CBB, & soccer content for FanDuel Research & USA Today. When he’s not writing, he enjoys cooking, watching movies, & playing video games.

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