After falling 2-1 against the Mets in a three-game series, the New York Yankees (28-19) have another rival on deck, as they open a four-game series against the Toronto Blue Jays (21-25) on Monday, May 18, at 7:05 p.m. ET.
According to PrizePicks Team Picks, the Yankees are the home favorite with a 1.53x payout if they win. However, New York has lost three consecutive series, while the Blue Jays defeated the Tigers in a 2-1 series win over the weekend.
Below, we'll break down our Blue Jays vs. Yankees prediction and picks for Monday’s MLB game, including the winner payouts, over/under, and key player picks for PrizePicks.
Make your Blue Jays vs. Yankees picks on PrizePicks for tonight's AL East clash.
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Blue Jays vs. Yankees Prediction, Winner, Over/Under – Monday, May 18
The Rays (30-15) continue to lead the AL East, while the Yankees are three games behind. The Blue Jays are in third place, sitting 9.5 games back from first place.
According to PrizePicks Team Picks, New York has the shortest payout (1.58x) to win the AL East, while Toronto’s 14.28x payout is tied with the Orioles for the third-lowest payout.
Make your MLB Predictions for the 2026 season on PrizePicks Team Picks.
The Blue Jays’ production is a far cry from last season, when they advanced to the World Series. FanGraphs credits Toronto with only 188 runs scored (tied for 24th), paired with a .303 wOBA (26th) and 91 wRC+ (tied for 25th).
In the last 10 games, the Jays have posted 4.1 runs per contest, but that’s elevated by 14 runs on May 9 vs. the Angels. If we exclude that matchup and look at nine of the last 10 games, Toronto recorded a measly 3.0 runs per game.
New York is putting SP Ryan Weathers on the mound for Game 1, and the left-handed pitcher touts a 3.00 ERA and 2.85 xFIP over eight starts. For the Jays, SP Patrick Corbin will be toeing the rubber with his 3.93 ERA and 4.56 xFIP over seven starts.
In a battle of southpaw starters, who could emerge with a win tonight?
Blue Jays vs. Yankees Winner Payout, Over/Under – Monday, May 18
The Yankees enter Monday’s matchup as a home favorite against the Blue Jays, returning a 1.53x payout if they win outright, via PrizePicks Team Picks.
Here are the full payouts for the Blue Jays vs. Yankees game on PrizePicks.
- Spread: New York Yankees -1.5 (2.08x payout)
- Over/Under: 8.5 (1.72x payout on Over)
- Game Winner Payout: Blue Jays 2.38x | Yankees 1.53x
Play the Blue Jays vs. Yankees winner or over/under on PrizePicks Team Picks to earn real money — available in 35 states!
Team Picks data is live at the time of writing and is subject to change.
Blue Jays vs. Yankees Prediction on Spread – 5/18/26
Here are the key game stats and trends behind our Blue Jays vs. Yankees prediction for the run line on Monday, May 18.
Lock in your Blue Jays vs. Yankees prediction on PrizePIcks before the first pitch.
- While the Yankees have stumbled of late, they produced 4.7 runs per game over the weekend vs. the Mets — which is a slight dip from 5.0 on the season.
- New York’s pitching has struggled by giving up at least 6 runs in three of the last four games.
- However, the Blue Jays have 46 runs scored (tied for 27th) with a .299 wOBA (21st) against left-handed pitching.
- Meanwhile, the Yankees do not slow down against southpaws, sporting 79 runs scored (tied for second) and a .344 wOBA (fourth).
- If Blue Jays SP Patrick Corbin has an early exit, he will hand the ball to a strong bullpen carrying a 3.41 xERA (fifth).
- However, Toronto’s relievers give up a 12.7% home run-to-fly ball ratio (28th), and New York boasts a 14.3% HR/FB (second).
Blue Jays vs. Yankees Player Picks, Stats for PrizePicks – 5/18/26
Here are top Blue Jays vs. Yankees picks to target on PrizePicks for Monday, May 18. Today’s MLB picks for PrizePicks include Kazuma Okamoto and Ryan Weathers.
Blue Jays 3B Kazuma Okamoto vs. Yankees: 5.5 Hitter Fantasy Score
- After batting only .200 in April, Kazuma Okamoto has hit .264 in May.
- Plus, he’s reached a 7.0 hitter fantasy score in two of his last three appearances.
- Okamoto’s production spikes against lefties, touting a .278 average compared to .220 when facing right-handed hurlers.
- Yankees SP Ryan Weathers’ most-used pitch is a four-seam fastball (30.0%), per Baseball Savant. The Jays’ third baseman hits .295 against this pitch.
- Plus, heaters may aid Okamoto’s power, fueled by his 93.2 average exit velocity (94th percentile), 15.3% barrel rate (89th percentile), and 54.1% hard-hit rate (95th percentile).
- Weathers permits an 11.5% barrel rate (14th percentile) and a 42.1% hard-hit rate (33rd percentile).
- The Yankees’ starter has also surrendered a 14.6% HR/FB that’s above the 10.8% league average.
- Okamoto’s 43.2% flyball rate and 20.8% HR/FB could be threats tonight.
Add Kazuma Okamoto to your PrizePicks Lineup now.
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Yankees SP Ryan Weathers vs. Blue Jays: 5.5 Strikeouts
- Baseball Savant gives Weathers an exceptional 29.8% strikeout rate (90th percentile), boosted by a 29.1% whiff rate (77th percentile) and a 32.0% chase rate (64th percentile).
- He’s posted 6.8 strikeouts per start, reaching at least 7 Ks in four of his past six outings.
- However, the Blue Jays have the lowest K rate in MLB (18.1%), and they rarely whiff with a 10.3% swinging-strike rate (10th-lowest).
- Weather’s sweeper carries an absurd 54.5% K%, and Toronto ranks 17th in runs above average against the pitch.
- In a tightly contested matchup, this K total may come down to how long Weathers is on the mound.
- He’s completed the fifth inning in six consecutive starts and pitched into the seventh in three of his last six appearances.
- The Blue Jays’ struggles against left-handed pitching may help his cause.
- Toronto has the third-lowest barrel rate (6.4%) and the fifth-lowest hard-hit rate (37.1%), perhaps limiting some of Weathers’ hard contact allowed.
Add Ryan Weathers to your PrizePicks Lineup now.
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Will the Yankees continue to struggle or finally get back on track against their AL East rival? The Blue Jays come off a series win, but it was against a sub-.500 team in the Tigers.
Don’t wait until the first pitch — make your Blue Jays vs. Yankees picks on PrizePicks now and earn real money if you’re right.
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