Best NFL Week 8 Picks Against the Spread: Back Rams in Battle of LA?

Week 8 of the 2026 NFL season has an action-packed 11-game slate on Sunday, November 1, all before Sunday Night Football gets underway. At first glance, a handful of underdogs are appearing as solid picks against the spread (ATS) on PrizePicks.

Before Week 8 NFL games kick off on Sunday, which teams are the best Week 8 NFL picks to cover the spread?

Below, we’ll discuss our favorite NFL Week 8 picks against the spread, featuring winner, spread, and over/under payouts on PrizePicks, with analysis on each game. including the Chargers vs. Rams in the Battle of Los Angeles.

Make NFL Week 8 picks on spreads on PrizePicks!

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Best NFL Week 8 Picks Against the Spread

Here are our best NFL Week 8 picks against the spread for Sunday, including each game’s payouts on PrizePicks Team Picks. NFL Week 8’s predictions include the Vikings, Raiders, and Rams.

PrizePicks payouts are live as of this writing and subject to change.

Vikings vs. Lions Prediction on Spread – Week 8 NFL Pick

One of the most anticipated matchups in Week 8 pits the Minnesota Vikings and Detroit Lions against each other in an NFC North battle. Despite ranking 31st in total touchdowns scored, the Vikings enter as the lone undefeated team in the NFL, while the Lions are sitting at third in the division with a 4-2 record.

Although Minnesota’s offense has left a lot to be desired with QB Kyler Murray, Detroit’s defense isn’t suddenly an elite unit after allowing fewer than 20 points for the first time this season in Week 7 against the Green Bay Packers.

At the same time, the Vikings have been historically great on defense, ranking first in EPA/play (-0.22) and success rate allowed (33.8%), per rbsdm.

While Lions QB Jared Goff carved the Packers’ defense for 303 yards and 2 TDs in Week 7, he was able to operate from a clean pocket often. Meanwhile, the Vikings’ defense is first in blitz rate (68.4%) and pressure rate (47.6%), so Goff may not have much time to survey the field and make his reads in the pocket.

Aside from Minnesota going 0-2 ATS as an underdog against Detroit last season, they have the fourth-best record ATS as the road team (7-3) since the start of 2025. On the other hand, the Lions are 2-4 ATS this season and are 4-6-1 ATS at home since last year.

Make your Vikings vs. Lions prediction for NFL Week 8 on PrizePicks!

Raiders vs. Jets Week 8 Prediction on Spread – Week 8 NFL Pick

After a 3-0 start to the season, the Las Vegas Raiders have lost four in a row. Despite the Raiders hitting a wall in recent weeks, they’re still 5-2 ATS this year, and they’ll face a reeling New York Jets squad in Week 8.

The Jets are coming off a devastating loss to the winless Miami Dolphins in Week 7, giving them a 1-5 record in their last five games. Additionally, New York is 2-3 ATS over their last five contests.

Even with QB Kirk Cousins slowing down recently, he’ll have a chance to bounce back against a Jets defense that is 24th in dropback EPA (0.14) and 23rd in dropback success rate (47.6%) in 2026. Before getting blown out by the Los Angeles Rams in Week 7, the Raiders had 3-point losses as underdogs against the Buffalo Bills and Kansas City Chiefs in two of their three previous games.

To begin the Klint Kubiak era in Sin City, the Raiders are 4-2 ATS as an underdog. Since Aaron Glenn was named the head coach of the Jets to begin the 2025 campaign, they are 1-2 ATS as favorites and 5-6 ATS at home.

Make your Raiders vs. Jets prediction for NFL Week 8 on PrizePicks!

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Chargers vs. Rams Week 8 Prediction on Spread  – Week 8 NFL Pick

Injuries continue to mount for the Rams, who entered the 2026 season as clear Super Bowl favorites. However, Los Angeles snapped a 2-game losing streak with a 35-21 victory over Las Vegas in Week 7.

With WR Davante Adams sidelined, the Rams are forming an identity of running their offense through WR Puka Nacua, RB Kyren Williams, and RB Blake Corum. Besides Williams and Corum combining for 192 rushing yards and 2 TDs against the Raiders, the Rams are 10th in rushing EPA (-0.04) and 6th in rushing success rate (45.0%) this season.

On the flip side, the Chargers are winless coming out of their bye week, and Jim Harbaugh’s team hasn’t shown any redeeming qualities. Even with lofty expectations when QB Justin Herbert joined forces with offensive coordinator Mike McDaniel this offseason, the Bolts’ offense is 32nd in EPA/play (-0.21) and 31st in success rate (36.9%)

The Chargers are an unbelievable 0-6 ATS to begin the 2026 season and are 0-9 ATS in their last nine games. As for the Rams, Sean McVay’s squad is 14-9 ATS as favorites since the start of last season.

Make your Chargers vs. Rams prediction for NFL Week 8 on PrizePicks!

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Make NFL Week 8 Picks Against the Spread on PrizePicks

Our NFL Week 8 picks comes down to two live underdogs and one favorite we trust. The Vikings and Raiders have the against the spread track records to keep it close or win outright, and the Rams draw a Chargers team that hasn’t covered in nine straight games.

Don’t wait until kickoff for this week of NFL action — make your 2026 NFL picks on PrizePicks now and earn real money if you’re right.

With the 2026 season nearing the midway point, just pick NFL players, predict More or Less on their stats, and cash in if you’re right. With Team Picks, you can make predictions on NFL game winners, spreads, over/unders, and award futures, now available in 36 states.

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