The 2026 NFL season kicked off by matching a Super Bowl-era record for the most combined Week 1 points per game at 49.4. Although the Kansas City Chiefs fell short of that mark vs. the Denver Broncos, the Indianapolis Colts and Baltimore Ravens made up for it by collectively lighting up the scoreboard in their matchup.
Now, K.C. and Indy square off under the bright lights of Sunday Night Football. We know that both sides boast star-studded rushing attacks, but could the passing game also be worth following in this one? There’s no shortage of options for your touchdown scorer picks tonight at 8:20 p.m. ET.
Below, we'll highlight our best Colts vs. Chiefs anytime TD scorer predictions for PrizePicks in Week 2, including three players who could reach the end zone on Sunday night.
Make your Colts vs. Chiefs Anytime TD scorer picks on PrizePicks now.
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Colts vs. Chiefs Anytime TD Scorer Picks for Sunday Night Football – September 20
When the Chiefs are at their best, they can score in bunches and boast one of the most fun offenses in the sport. The Colts flashed that ability en route to their 7-1 start last season, and both teams will be eager to recapture their peak form and score some TDs in Week 2.
Anytime TDs on PrizePicks include rushing, receiving, recoveries, and returns. PrizePicks often list Anytime TDs as Demons and Goblins, meaning users can only select "More." For standard projections, users can select “More” or “Less.”
Demons are tougher to win but are the only way to get higher payouts. Meanwhile, Goblins are lower than a standard projection, but they are easier to win, so there’s a lower payout.
Colts RB Jonathan Taylor vs. Chiefs: 0.5 Anytime TDs (Goblin)
- Taylor led the sport in rushing TDs in 2025 with 18, also topping the league in first downs gained (84) and carries (323) on the ground. He’s a volume extraordinaire.
- Via NFL Pro, Taylor created 61 yards before contact to open the season, which was more than he had in any game last year.
- Taylor logged each of the Colts’ 5 red-zone rushing attempts in Week 1, scoring both of his touchdowns inside the 10-yard line.
- The superstar halfback forced a staggering 68 missed tackles this past campaign, per Pro Football Focus, and had 36 rushes of 10+ yards.
- While Kansas City did limit Denver to just 58 rushing yards in the regular-season opener, the host team’s 6.7% run-stuff rate was tied for the fifth-lowest among all 32 teams.
Add Jonathan Taylor + Colts to win to your PrizePicks lineup now.
Chiefs RB Kenneth Walker III vs. Colts: 0.5 Anytime TDs (Goblin)
- In his first game as a Chief, Walker toted the ball a whopping 23 times and forced 14 missed tackles, racking up 117 yards after those whiffs.
- Walker ran outside zone on 34.8% of his carries vs. the Broncos. In their Week 1 game vs. Baltimore, the Colts ceded 3 rushing TDs and 6.2 yards per carry when facing that concept.
- Kansas City made a concerted effort to get Walker involved in the passing game, too, as evidenced by his 6 targets, 3 receptions, 18 yards, and a TD.
- According to ESPN, the Colts were a horrid 30th in run stop win rate (23%) in Week 1.
- RBSDM relays that Indianapolis’ 0.101 rush EPA per play allowed through one game is 26th leaguewide.
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Add Kenneth Walker III + Chiefs to cover the spread to your PrizePicks lineup now.
Chiefs QB Patrick Mahomes vs. Colts: 0.5 Anytime TDs (Demon)
- Mahomes scrambled twice on pressured dropbacks last week, with one of them resulting in his first-quarter TD.
- Via SumerSports, out of 37 QBs with 250+ dropbacks in 2025, Mahomes’ 9.0% scramble rate ranked sixth.
- #15 was a factor in the red zone last year, carrying the ball 14 times (16.9% of the Chiefs’ red-zone rushes) and winding up with 5 TDs as a result.
- Indianapolis surrendered 7 rushes for 40 yards and a TD to Ravens QB Lamar Jackson last Sunday, contributing to the seventh-most fantasy points per game yielded to the position thus far.
- Per Sharp Football Analysis, the Colts led the NFL in man coverage rate (46.9%) in Week 1. Mahomes owns the 26th-ranked passer rating against man since the beginning of 2025, which could mean he runs more.
Add Patrick Mahomes + Chiefs to win to your PrizePicks lineup now.
Make Colts vs. Chiefs Picks on PrizePicks
Coming off an electric Kansas City debut, Walker aims to prove that he’s the driving force behind the Chiefs returning to dominance. Elsewhere, it’s hard to ever count Taylor out, even against a defense that bottled up Denver’s rushing attack last Monday.
Don’t wait until kickoff — make your Colts vs. Chiefs picks on PrizePicks now and earn real money if you’re right.
Pick players, predict More or Less on their stats (including anytime TDs), and cash in if you’re right. With Team Picks, you can make predictions on NFL game winners, spreads, and over/unders, now available in 36 states.
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