Atlético Madrid vs. Man United Prediction, Picks, XIs for Champions League

October 13, 2026

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Soccer
AP Photo/Bernat Armangue
Atlético Madrid ST Jonathan David takes a shot during warmups before a La Liga match vs. Real Madrid.

Tuesday’s Champions League match between Atlético Madrid and Manchester United kicks off at 3:00 p.m. ET. Atlético Madrid enters the Champions League match as slight favorites on their home pitch, with a 1.88x payout on PrizePicks.

Atlético Madrid will look to stay unbeaten at home this season when they host English side Manchester United at the Metropolitano on Tuesday afternoon. Man United had a dominant 4-0 win in their Champions League opener and now seek to upset their Spanish hosts on Matchday 2.

Below, we'll break down our Atlético Madrid vs. Man United prediction and picks for Tuesday's Champions League match, including UCL winner payouts, total goals, and top Champions League picks for PrizePicks today.

Make your Atlético Madrid vs. Man United prediction on PrizePicks now!

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Atlético Madrid vs. Man United Prediction, Picks for Champions League – Tuesday, October 13

Atlético Madrid enters Tuesday’s game as home favorites against Manchester United, returning a 1.88x payout if they win outright, via PrizePicks Team Picks.

Meanwhile, Man United will look to pull off a massive upset as road underdogs, with their 3.44x payout to win. PrizePicks also has a 3.44x payout on a draw between the two sides.

Here are the full payouts for the Atlético Madrid vs. Man United game on PrizePicks. PrizePicks data is live at the time of writing and is subject to change.

Winner Spread Both Teams to Score
Atlético Madrid 1.88x -1.5 | 3.22x Yes | 1.56x
Man United 3.44x +1.5 | 1.31x No | 2.32x
Make your Atlético Madrid vs. Man United prediction on total goals on PrizePicks!

How to watch Atlético Madrid vs. Man United: Paramount+ (English), UniMas (Spanish)

Kickoff Time: 3:00 p.m. ET

Venue: Riyadh Air Metropolitano, Madrid, Spain

Club football returned this past weekend after a two-week international break that began at the end of September. Matchweek 2 of the Champions League kicks off on Tuesday afternoon, more than a month after each club’s opening fixture in the competition.

One of the afternoon’s most compelling matchups sees Manchester United travel to the Spanish capital to take on Atlético Madrid.

These teams last met competitively in the 2022 Champions League Round of 16, when Atlético eliminated the Red Devils 2-1 on aggregate. United returned to the competition in 2023 but has been absent since, playing their first UCL game in three years back in September.

They will look to carry the goal-scoring form from that Matchday 1 win into Tuesday, though their poor domestic form in the Premier League makes that a difficult ask.

United have won just once in the Premier League this season and arrive in Spain fresh off a 1-1 draw against a 10-man Tottenham side. Since their 4-0 win over Sabah on September 13, they have lost or drawn four straight, heading into one of the most difficult away fixtures in European football.

Atlético have lost just eight of 63 home matches in the Champions League under Diego Simeone and have started the season 3-1-0 at the Metropolitano, most recently defeating city rivals Real Madrid.

Atlético have been far more consistent domestically, sitting second in La Liga with six wins from eight games. Despite internal tensions surrounding superstar ST Julián Álvarez, Simeone has gotten the best out of his new signings, and the Spanish club will have genuine ambitions of challenging for the UCL title after reaching the semifinals last season.

While United have the quality to nick a result in Spain, they are simply not playing at the level we saw under Michael Carrick last season. Atlético’s home record makes them a formidable opponent for anyone — especially this United side on Tuesday afternoon.

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Atlético Madrid vs. Man United Prediction on Total Goals – 10/13/26

Here are the key game stats and trends behind our Atlético Madrid vs. Man United prediction on total goals for the Champions League match on Tuesday, October 13.

Check out more of our Champions League picks and predictions on PrizePicks.

  • Atlético Madrid scored 2 or more goals in seven of their nine games across all competitions this season. They managed just 1 in the UCL opener against Liverpool and generated just 0.91 xG against their other European opponent.
  • United kept just one clean sheet across all competitions this season — the 4-0 win over Sabah on Matchday 1. The Red Devils are conceding 1.5 goals per game in the Premier League.
  • Atlético have kept three clean sheets in La Liga and held opponents to 1 goal or fewer in six of nine matches across all competitions.
  • Atlético arrive at Matchday 2 on a four-game winning streak, outscoring opponents 11-2 in that stretch. United conceded 6 goals domestically over that same period.
  • Manchester United scored 15 goals across eight games this season. About 60.0% of those came in just two fixtures — the 4-0 win over Sabah and the 5-2 win over Ipswich — leaving just 6 goals in the remaining six games.
Predict Atlético Madrid vs. Man United total goals in this Champions League match on PrizePicks!

Atlético Madrid vs. Man United Projected Lineups for Champions League – Tuesday, October 13

Take a look at the Atlético Madrid vs. Man United projected lineups for today's Champions League match. Lineups are not official and should be confirmed before match start.

Atlético Madrid Lineup vs. Manchester United: Projected 4-4-2

Goalkeeper: Jan Oblak

Defense: Marc Pubill, Cristian Romero, Dávid Hancko, Alejandro Grimaldo

Midfield: Giuliano Simeone, Alejandro Baena, Marcos Llorente, Johnny Cardoso

Forwards: Jonathan David, Kang-in Lee

Manchester United Lineup vs. Atlético Madrid: Projected 4-2-3-1

Goalkeeper: Senne Lammens

Defense: Lisandro Martínez, Harry Maguire, Leny Yoro, Diogo Dalot

Midfield: Carlos Baleba, Youri Tielemans, Bruno Fernandes

Forwards: Marcus Rashford, Matheus Cunha, Bryan Mbeumo


Atlético Madrid vs. Man United Player Picks, Stats for PrizePicks: 10/13/26

Here are Atlético Madrid vs. Manchester United picks to target for the Champions League match on PrizePicks for Tuesday, October 13. Today’s Champions League picks include Jonathan David and Senne Lammens.

Atlético Madrid ST Jonathan David vs. Man United

Projection via PrizePicks: 0.5 Goals (Demon), 2.5 Shots (Goblin), 0.5 Assists (Demon)

  • Jonathan David has stepped up in Simeone’s system with Álvarez’s minutes being purposefully limited. The Canadian ST now has 5 goal contributions in just four La Liga appearances for the club.
  • David scored in three straight La Liga games, including the winner against Real Madrid, before the international break. He failed to score in his first game back against Alavés but contributed an assist in just 45 minutes.
  • Despite playing just 205 minutes for the club, he leads the team in xG (2.44), assists (2), total shots per game (2.8), and shots on target per game (1.8) in La Liga.
Add Jonathan David to your PrizePicks lineup now!

Man United GK Senne Lammens vs. Atlético Madrid: 3.5 Goalie Saves

  • Lammens was one of the standout goalkeepers during the international break but has been less impressive at club level this season. He is averaging 3.0 saves per game in the Premier League and has exceeded that mark in just two appearances.
  • He faces an Atlético Madrid attack averaging 6.5 shots on target per game in La Liga this season. The last three goalkeepers to face Atlético have averaged 5.67 saves per game.
  • Lammens demonstrated his ceiling during Nations League play, averaging 6.33 saves per game before returning to United over the weekend and making 2 saves in the draw against Tottenham.
Add Senne Lammens to your PrizePicks lineup now!

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Make Atlético Madrid vs. Man United Predictions on PrizePicks

Atlético Madrid will look to claim their first Champions League win of the season when they host Manchester United on Tuesday, October 13, at 3:00 p.m. ET. United arrive in the Spanish capital in poor form and hope to upset the hosts, handing Atlético their first home defeat of the season.

Don’t wait until kickoff — make your Atlético Madrid vs. Man United picks for Tuesday’s Champions League match now on PrizePicks to earn real money. 

Just pick your Champions League players, predict More or Less on their stats, and cash in if you’re right. With Team Picks, you can make predictions on match winner, total goals, and both teams to score — now available in 36 states. 

Stay locked in with the Playbook for continued soccer and Champions League predictions, picks, and analysis.

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Anthony is a journalist based in South Florida who specializes in sports content. He has covered the NFL, NBA, UFL, March Madness, the World Cup, the English Premier League, and the Champions League.