Arizona State vs. #10 Texas A&M Prediction, Spread, NCAAF Picks – Saturday, September 12

The Arizona State Sun Devils vs. Texas A&M Aggies game is set to kick off at 12 p.m. ET on Saturday, September 12 at Kyle Field in College Station. The Aggies enter as 14.5-point home favorites, via PrizePicks. 

Both these teams rolled to 50+ point routs in their season openers last week. Texas A&M shut out Missouri State 50-0 as 38.5-point favorites in its first game since getting eliminated in the College Football Playoff by Miami. The Sun Devils destroyed Morgan State 70-7 as 43.5-point favorites, racking up 681 yards in the victory. It marked the third time in the last four seasons that ASU opened with an FCS opponent.

Below, we'll break down our Arizona State vs. Texas A&M prediction and picks for Saturday's college football game, including the winner, over/under, and key player picks for PrizePicks.

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Arizona State vs. #10 Texas A&M Prediction, Spread, Over/Under – Saturday, September 12

The Aggies posted plenty of strong metrics last season on their way to the CFP. A&M ranked seventh in net adjusted EPA per play and 20th in offensive success rate. On the defensive side, the Aggies were the top team in late-down success rate and fourth in defensive success clip, according to Game on Paper.

The Sun Devils had wholesale changes on the offensive side of the ball, starting with the departure of QB Sam Leavitt to LSU. RB Raleek Brown transferred to Texas following a 1,141-yard campaign, while top WR Jordyn Tyson was drafted eighth overall by the New Orleans Saints.

QB Cutter Boley made his ASU debut following a two-year tenure at Kentucky, compiling 387 passing yards and 6 TDs with a total EPA of 21.09. Granted, it was against an FCS school, but it marked his second career performance of at least 3 TD passes.

Texas A&M ran 47 more plays from scrimmage than Missouri State, while holding the Bears to 74 yards on 30 plays from scrimmage. The Aggies posted an EPA of 21.33 and limited Missouri State to -22.84.  

Last season’s top WR, KC Concepion, headed to the Cleveland Browns with a late first-round pick. Despite that, second-leading Aggies WR Mario Craver returned after a 917-yard output in 2025. 

Arizona State vs. Texas A&M Spread, Over/Under – Saturday, September 12

The Aggies enter Saturday’s game as 14.5-point favorites against the Sun Devils. ASU returns a hefty 5.55x payout if it wins outright, via PrizePicks Team Picks.

Here are the full payouts for the Arizona State vs. Texas A&M game on PrizePicks.

Play the Arizona State vs. Texas A&M winner or over/under on PrizePicks Team Picks.

Team Picks data is live at the time of writing and is subject to change.

Arizona State vs. Texas A&M Prediction on Spread – 9/12/26

Here are the key game stats and trends behind our Arizona State vs. Texas A&M prediction on the spread for Saturday, September 12.

• Although the Sun Devils lit up Morgan State, ASU closed 2025 owning the 108th-ranked offensive success rate.
• Arizona State did cover the spread in four of six opportunities as an underdog last season.
• The last time the Sun Devils closed as a double-digit underdog, they nearly shocked Texas in the 2024 CFP in a 39-31 double-overtime defeat.
• Since 2023, the Aggies are 1-7 against the spread as a double-digit home favorite against non-SEC foes.
• In a quirky stat, A&M ranked last nationally in net field position (-11.0) in 2025 but managed a +11.0 rate in the rout of Missouri State.
• Since their move to the Big 12 in 2024, the Sun Devils are 7-4 on the road, including a loss at Mississippi State last season.

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Arizona State vs. Texas A&M Picks, Player Stats for PrizePicks: 9/12/26

Here are top Arizona State vs. Texas A&M picks to target on Saturday, September 12. Today’s college football picks for PrizePicks include RB Kyson Brown and QB Marcel Reed.

Arizona State RB Kyson Brown vs. Texas A&M: 41.5 Rush Yards

• The senior is getting an opportunity after racking up 583 yards through his first three seasons.
• Brown rushed for 80 yards on only 6 carries against Morgan State, highlighted by a 46-yard scamper.
• A&M shut down a Missouri State squad that ranked 102nd in EPA/rush last season, but ASU placed 29th in that category.
• Brown played four games last season before an ankle injury sidelined him. The last time he posted more than 42 rushing yards was a career-best 100 yards against Arizona in 2024. 

Add Kyson Brown to your PrizePicks lineup now.

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Texas A&M QB Marcel Reed vs. Arizona State: 240.5 Pass Yards

• Reed put up 233 passing yards against Missouri State, marking the sixth time in the last seven games he compiled fewer than 240 yards.
• The Sun Devils allowed at least 241 passing yards to six QBs last season and ranked second among Big 12 teams in yards allowed per dropback (5.77).
• Via Game on Paper, Reed's 7.88 yards per dropback in 2025 ranked 18th among all qualified passers.
• In the game against the Bears, the star signal-caller led the Aggies to 0.35 EPA/dropback, placing them in the 78th percentile.

Add Marcel Reed to your PrizePicks lineup now.

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The Sun Devils and Aggies each rolled to home victories in their season openers last week. Can Arizona State cash as a heavy underdog, or will Texas A&M put together another terrific defensive performance at Kyle Field? 

Don’t wait until lock — make your Arizona State vs. Texas A&M picks on PrizePicks now and earn real money if you’re right.

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