USA vs. Senegal Prediction, Picks, XIs for International Friendly – 5/31/26

Sunday’s international friendly match between the USA and Senegal is set to kick off at 3:30 p.m. ET on TNT and truTV. The USA enters the friendly match as slight favorites on their home pitch, with a 2.43x payout to win on PrizePicks. 

The US Men's National Team hosts Senegal at Bank of America Stadium in Charlotte as both sides prepare for the 2026 World Cup. Sunday's match is the first of two pre-tournament friendlies for both sides ahead of the tournament's June 11 start.

Below, we'll break down our USA vs. Senegal prediction and picks for Sunday's international friendly match, including the winner payouts, total goals, and top picks for PrizePicks today.

Make your USA vs. Senegal picks on PrizePicks for Sunday's international friendly match now.

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USA vs. Senegal Prediction, Picks for International Friendly – Sunday, May 31

Fans of the USMNT are eager to see what lineup manager Mauricio Pochettino rolls out for the team's first game since late March. Pochettino has yet to settle on a first-choice lineup heading into the World Cup, drawing consistent criticism.

With just two friendlies before the group stage, Pochettino will likely use Sunday's match to continue experimenting, having yet to settle on a preferred system. Pochettino initially favored a 4-2-3-1 after taking charge but has recently shifted toward a 3-4-2-1 with a back three.

USA vs. Senegal should be evenly matched. Both sides have slipped in the FIFA rankings recently, with Senegal sitting 14th, the highest of all African teams, and the USMNT 16th, just behind Mexico. Sunday's match will be the first meeting between the two nations.

Senegal's supporters have more reason for optimism heading into the World Cup than their American counterparts. Pape Thiaw's side has been in strong form over the past couple of months, including a controversial appearance in the AFCON Final against Morocco. 

Senegal's squad blends experienced veterans like F Sadio Mane with exciting young talent such as CB Mamadou Sarr. The African side was drawn into what many consider this year's Group of Death alongside France, Norway, and Iraq. 

Sunday's friendly gives both sides a useful gauge of where they stand against quality opposition before the tournament begins. Based on recent form, Senegal figures to be the better-organized side, as Pochettino continues to tinker with the USA lineup.

USA vs. Senegal Winner, Total Goals, Payouts – Sunday, May 31

USA enters Sunday’s game as home favorites against Senegal, returning a 2.43x payout if they win outright, via PrizePicks Team Picks.

Here are the full payouts for the USA vs. Senegal game on PrizePicks.

• Winner Payout: USA – 2.43x | Tie – 3.22x | Senegal – 2.5x
• Total Goals: 2.5 (Over – 2.13x)
• Both Teams to Score: Yes 1.87x | No 1.87x

‍Make your USA vs. Senegal prediction on winner or total goals on PrizePicks Team Picks to earn real money — available in 35 states!

Team Picks data is live at the time of writing and is subject to change.

USA vs. Senegal Prediction on Winner – 5/31/26

Here are the key game stats and trends behind our USA vs. Senegal prediction for the winner in the international friendly match on Sunday, May 31.

A Senegal upset over the USA on Sunday features a 2.5x payout if they win on PrizePicks Team Picks — available in 35 states.

Lock in your USA vs. Senegal prediction on PrizePicks before match start.

• Senegal has gone unbeaten in its last nine matches, though the AFCON Final win over Morocco was later voided by CAF due to a technicality, which now counts as a loss in the official record.
• The African side was dominant throughout AFCON, conceding just 2 goals across its seven matches.
• After a solid run of form late last year, the USMNT's most recent outings in March were back-to-back losses to Portugal and Belgium. The US conceded 7 goals across those two defeats, scoring just twice.
• In his two major tournaments, Pochettino has led the US to a semifinal exit and a final loss. The USMNT has yet to win a trophy during Poch’s tenure.
• The US scored a tournament-high 13 goals in the most recent Gold Cup before falling 2-1 to Mexico in the final.

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USA vs. Senegal Projected Lineups for Sunday, May 31

Take a look at the USA vs. Senegal projected lineups for today's international friendly match. Lineups are not official and should be confirmed before match start.

USA Lineup vs. Senegal: Projected 3-4-2-1

Goalkeeper: Matthew Freese

Defense: Auston Trusty, Chris Richards, Alexander Freeman

Midfield: Antonee Robinson, Weston McKennie, Tyler Adams, Tim Weah

Forwards: Ricardo Pepi, Folarin Balogun, Christian Pulisic

Senegal Lineup vs. USA: Projected 4-3-2-1

Goalkeeper: Edouard Mendy

Defense: El Hadji Malick Diouf, Moussa Niakhate, Mamadou Sarr, Krepin Diatta

Midfield: Pape Gueye, Idrissa Gana Gueye, Pape Matar Sarr

Forwards: Sadio Mane, Nicolas Jackson, Iliman Ndiaye

Make USA vs. Senegal Picks on PrizePicks

The USMNT will look to build some chemistry and momentum ahead of the 2026 World Cup when they host Senegal on Sunday at 3:30 p.m. ET. Senegal hopes to iron out any remaining issues ahead of what could be its deepest World Cup run yet.

Don’t wait until kickoff — you can make your USA vs. Senegal picks for Sunday’s international match now on PrizePicks and PrizePicks Team Picks to earn real money. 

Just pick your players, predict More or Less on their stats, and cash in if you’re right. With Team Picks, you can make predictions on match winner, total goals, and both teams to score – now available in 35 states. 

Stay locked in with the Playbook for continued soccer and 2026 World Cup predictions, picks, and analysis.