The NBA preseason is in full swing with five games on the slate on Wednesday, October 7. One game that could draw significant attention is the Minnesota Timberwolves taking on the Indiana Pacers at 7 p.m. ET on NBA TV.
The Timberwolves are 5.5-point road favorites on Wednesday, via PrizePicks. Minnesota began its preseason with a 116-97 win over the Milwaukee Bucks on Monday, while Wednesday’s contest marks Indiana's first preseason matchup.
Let’s jump into tonight’s NBA preseason contest, highlighted by our Timberwolves vs. Pacers prediction and picks for Wednesday, including NBA player projections on PrizePicks.
Make your Timberwolves vs. Pacers picks for the NBA preseason on PrizePicks!
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Timberwolves vs. Pacers Prediction, Winner, Over/Under for NBA Preseason – Wednesday, October 7
The Pacers begin their preseason by welcoming back G Tyrese Haliburton to the court for the first time in 16 months. Ironically, Haliburton will make his long-awaited return at the Hilton Coliseum in Ames, Iowa, where he played for Iowa State in two seasons.
Haliburton tore his right Achilles tendon in Game 7 of the 2025 NBA Finals and missed the entire 2025-26 season to recover. The Pacers star did compete in the team’s annual Pacers FanJam scrimmage on Sunday, scoring 8 points and dishing out 4 assists in a 12-minute showcase.
Meanwhile, despite finishing with the second-fewest wins (19) in the NBA in 2025-26, the Pacers still made a splash at the trade deadline. Indiana landed C Ivica Zubac in a trade involving wing Bennedict Mathurin and multiple first-round picks.
Zubac started just five games with the Pacers last season because of ankle and rib injuries. The Pacers tallied the sixth-fewest rebounds per game (41.9), and Zubac should help considerably on the glass.
Since this is Indiana’s first preseason contest, the team may roll with its expected regular-season starting five: Haliburton, G Andrew Nembhard, F Aaron Nesmith, F Pascal Siakam, and Zubac.
Meanwhile, in the Timberwolves’ preseason opener on Monday, G LaMelo Ball made his Minnesota debut after the team acquired him in a four-team trade with the Charlotte Hornets in July. Ball scored 11 points on 3-of-6 shooting, grabbed 4 rebounds, and dished out 3 assists in 17 minutes. The former Rookie of the Year had a chance to share the floor with new teammate, SG Anthony Edwards, who scored 14 points in 18 minutes.
It’s unclear if the Timberwolves plan to play a significant number of their starters since they did play against the Bucks. While Minnesota had an off day on Tuesday, head coach Chris Finch might decide to give some players night off on Wednesday.
The Timberwolves will be without G Donte DiVincenzo on Wednesday, as he's still recovering from a torn Achilles tendon he suffered in the 2026 NBA playoffs.
Timberwolves vs. Pacers Winner Payout, Over/Under – Wednesday, October 7
The Timberwolves enter Wednesday’s preseason game as 5.5-point road favorites against the Pacers and return a 1.66x payout if they win outright, via PrizePicks.
Here are the full payouts for the Timberwolves vs. Pacers game on PrizePicks, including winner payouts, the spread, and over/under.
Make your Timberwolves vs. Pacers prediction on the over/under on PrizePicks.
PrizePicks data is live at the time of writing and is subject to change.
Timberwolves vs. Pacers Prediction on Over/Under for NBA Preseason – 10/7/26
Here are the key stats and predictions behind our Timberwolves vs. Pacers prediction on the over/under for Wednesday’s NBA preseason game.
- Despite scoring 116 points in Monday’s opener, the Timberwolves shot just 25.7% (9-of-35) from 3-point land against the Bucks. Ball and G Antonio Reeves were the only two Minnesota players who connected on multiple treys, drilling two shots apiece from beyond the arc.
- If Ball or Edwards plays limited minutes, the Timberwolves may not enjoy as much perimeter success.
- The Timberwolves were a sound defensive unit in 2025-26, holding their opponents to 46.2% shooting per contest (seventh in the NBA).
- It’s hard to imagine the Pacers having Haliburton play a substantial amount of minutes in his first game back. As a result, it’s possible that Indiana’s first unit won’t get a ton of time together.
- The under is 7-3 in the last 10 regular-season meetings between the Timberwolves and Pacers.
Lock in your Timberwolves vs. Pacers prediction on PrizePicks before tip-off.
Timberwolves vs. Pacers Picks, Player Stats on PrizePicks: 10/7/26
Our top Timberwolves vs. Pacers player picks for the NBA preseason on PrizePicks include Anthony Edwards and Andrew Nembhard.
Timberwolves SG Anthony Edwards vs. Pacers: 14.5 Points
- It’s no secret that Edwards has been a volume shooter throughout his NBA career. In fact, according to databallr, the Timberwolves star averaged 31.8 true shot attempts per 100 offensive possessions (99th percentile).
- Edwards spent 34.0% of his time on the floor on the ball this past season, ranking in the 99th percentile.
- The former No. 1 pick shot a career-best 39.9% from deep in 2025-26 on 8.4 attempts per contest.
- Despite only playing 18 minutes in the Timberwolves’ preseason opener, Edwards still fired up 13 shots in a limited window.
- The Pacers allowed their opponents to shoot 35.5% from beyond the arc last season (14th).
Add Anthony Edwards + Timberwolves to win to your PrizePicks lineup now.
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Pacers G Andrew Nembhard vs. Timberwolves: 12.5 Pts + Rebs + Asts
- Nembhard had a career year in 2025-26, setting personal bests in points per game (16.9), assists per game (7.7), and 3-point shooting (36.1%).
- The former second-round pick registered 20.2 potential assists per 100 offensive possessions, placing him in the 88th percentile.
- Nembhard spent 38.6% of the time as Indiana’s primary ball-handler a year ago, leading to many playmaking opportunities.
- The Pacers guard excels at getting to the basket, averaging 4.1 potential assists at the rim per 100 offensive possessions (83rd percentile).
Pick Andrew Nembhard + Pacers to cover the spread to your PrizePicks lineup now..
Make Timberwolves vs. Pacers Picks on PrizePicks
The NBA will descend upon Ames, Iowa, for Wednesday’s contest between the Timberwolves and Pacers. Despite potentially playing limited minutes, Edwards and Nembhard could have opportunities to thrive.
Don’t wait until tip-off — make your Timberwolves vs. Pacers picks on PrizePicks now and earn real money if you’re right. Pick players, predict More or Less on their stats, and cash in if you’re right. With Team Picks, you can make predictions on NBA game winners, spreads, and over/unders, now available in 36 states.
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