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Spurs vs Lakers Prediction, Spread: Wemby Tussles with the King

Spurs C Victor Wembanyama blocks a shot by Lakers F LeBron James in an NBA game.
AP Photo/Darren Abate

The San Antonio Spurs and Los Angeles Lakers, two teams in the thick of the Western Conference playoff race, meet on Thursday night in Los Angeles. It’s a matchup with plenty of star power, with Victor Wembanyama going up against LeBron James. The Spurs-Lakers Tuesday night game is at 10:30 p.m. ET on NBA TV.

The Spurs have won four straight games and sit a season-high 20 games over .500, facing a Lakers team that has won three of the last four, despite missing G Luka Doncic. The Spurs are in second place in the Western Conference, behind the Thunder, while the Lakers are fifth. 

Below, we’ll break down our Spurs vs. Lakers prediction and spread for Tuesday’s game. Make your picks on PrizePicks and PrizePicks Team Picks and earn real money if you’re right, including on game winners, spreads, and totals.

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Spurs vs. Lakers Prediction, Spread, Over/Under

The Spurs and Lakers franchises, who combined for 11 NBA titles from 1999 to 2020, meet for the fourth time this season. The Spurs have won the last two games, while the Lakers won the first meeting by two points. The teams have met 195 previous times in the regular season, with the Lakers holding a slim 99-96 lead.  

Spurs vs. Lakers Over/Under, Spread

The Spurs enter the Eastern Conference game as 8.5-point favorites, returning a 1.29x payout on PrizePicks Team Picks if they win.

The Lakers are the underdogs with a 3.22x payout if they win, via PrizePicks Team Picks.

  • Spread: San Antonio Spurs  -8.5
  • Over/Under: 228.5
  • Game Winner Payout: Lakers 3.22x | Spurs 1.29x

Team Picks data is live at the time of writing and is subject to change.


Spurs vs. Lakers Prediction on Spread

The Lakers are an 8.5-point underdog tonight, the largest home dog they have been all season. 

  • The Spurs are 28-23-2 against the spread this season, covering in each of their last four games. 
  • San Antonio is 17-17-2 this season as a favorite, including a 5-7-1 record as a road favorite. 
  • San Antonio has played 32 of 53 games (including the NBA Cup Final) under the posted number. The 32 unders are the third most in the NBA. 
  • However, the past three Spurs games have gone over the total, ending a streak of seven straight and 15 of 16 that had gone under. 
  • The Spurs are led by their defense, which is third in the league in defensive rating (111.21), fourth in opponents’ FG pct (45.5), and third in rebounds (46.6).
  • The Lakers, on the other hand, lead the NBA in FG pct (49.9%), are second in the NBA in EFG (57.0), and 11th in offensive rating (116.4).
  • The Lakers are 29-23 against the spread this season, the sixth-best cover percentage in the NBA.
  • L.A. is 8-12 against the number as an underdog this season, including 2-4 ATS as a home dog.

Spurs vs. Lakers Injury Report

Let’s dive into the full Spurs vs. Lakers injury report for Thursday, via NBA.com 

Spurs Injury Report 

  • F Lindy Waters III (Knee) - OUT

Lakers Injury Report

  • Unavailable as of publication

Spurs vs. Lakers Picks for PrizePicks Today: Tuesday, February 10

Here are two 76ers vs. Lakers picks to target for Tuesday, February 10 on PrizePicks. Player stat projections via PrizePicks are headlined by Spurs C Victor Wembanyama and Lakers F LeBron James

Spurs F Victor Wembanyama Projection vs. Lakers: 10.5 Rebounds

  • Spurs F Victor Wembanyama failed to hit his rebound projection in four of his last five games. 
  • The past two games, the projection was 11.5, with Wemby going for 11 rebounds, just missing the number. He has 36 total rebounds over the last three games, for an average of 12 per game.  
  • The big man is averaging 11.1 rebounds per game this season, sixth in the NBA.
  • In eight career games vs. the Lakers, he is averaging 11.5 rebounds per game. In the two games this season, Wemby has pulled down 14 and 8 rebounds. 

Lakers F LeBron James Projection vs. Spurs: 8.5 Assists

  • Lakers F LeBron James has reached his assist projection in four straight contests after failing to reach it in the previous six games. 
  • Over the last four games, James has 10, 10, 10, and 7 assists for an average of  9.25 per game.
  • Tonight’s assist projection of 8.5 assists is the highest of the season for the Lakers superstar. Per Betting Pros, you have to go back to February 22 of last season for the last time it was 8.5.
  • The future Hall-of-Famer has averaged 7.9 assists in 47 career games vs. the Spurs.  

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Make Spurs vs. Lakers NBA Picks on PrizePicks

Can the Spurs continue their winning streak and stay within striking distance of the Thunder at the top of the Western Conference? Or will the Lakers rebound from their loss to the top-seeded Thunder and knock off the team with the second-best record in the West?

You can make your Spurs-Lakers picks on PrizePicks and PrizePicks Team Picks to earn real money. Just pick players, predict More or Less on their projected stats, and cash in if you’re correct. With Team Picks, make predictions on winners, spreads, and over/unders, now available in 34 states

Get in the game! Sign up for PrizePicks and cash in on your sports predictions. Play $5 and get $50 instantly in Lineups with promo code PLAYBOOK.

Team Picks and Culture Picks are event contracts offered by Performance Predictions II, LLC d/b/a PrizePicks Predict, a CFTC-registered FCM and NFA Member. All event contract customers must be U.S. residents and 18+. Some event contracts may not be available in every state. Event contract trading carries significant risk and is not appropriate for everyone. No guarantee against loss is offered. Past results are not necessarily indicative of future results. Void where prohibited by law. Restrictions apply. For full terms of service see prizepicks.com/predict-regulatory. Team and Culture Pick Early Payouts subject to market liquidity. The content provided is for informational and educational purposes only and does not constitute investment advice, or a recommendation to trade any commodity interest.

about the author

David Bearman spent 18 years with ESPN in their Stats & Information Department and overseeing their betting content. From 2023-25, he served as Chief Content Officer of Pro Football Network, overseeing all content, including coverage of Super Bowls 58 and 59. He is also the Founder of Betting with Bearman, a 3x a week betting newsletter and weekly podcast on Bleav Podcast Network.

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