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Raptors vs. Clippers Prediction, Spread, NBA Picks for Wednesday, March 25

Toronto Raptors PF Scottie Barnes reacts to a call during a game against the Portland Trail Blazers.
AP Photo/Howard Lao

A whopping 24 of the NBA’s 30 teams take the court on Wednesday night, presenting wire-to-wire action for hoops fans to enjoy. At 10:30 p.m., the slate is capped off by a battle between the Toronto Raptors and Los Angeles Clippers.

With both teams looking to solidify their places in the postseason picture, this interconference clash carries plenty of weight.  

Below, we’ll break down our Raptors vs. Clippers prediction and picks for Wednesday night’s game. Make your NBA picks on PrizePicks and PrizePicks Team Picks and earn real money if you’re right, including on game winners, spreads, and totals!

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Raptors vs. Clippers Prediction, Spread, Over/Under

Under head coach Darko Rajakovic, the Raptors are experiencing some legitimate year-over-year improvement. After winning just 30 games and missing the play-in tournament last season, Toronto is 40-31 to this point and occupies the Eastern Conference’s No. 5 seed.

The Clippers, meanwhile, have slid compared to last season’s 50-win effort. With that said, head coach Tyronn Lue’s crew responded from a dreadful 6-21 start and is squarely in the play-in picture. L.A. enters Wednesday at an even 36-36.

Wednesday marks just the 60th all-time regular-season meeting between these two franchises. It’s a close-knit series, with the Raptors leading 30-29. 

Raptors vs. Clippers Spread, Over/Under

The Raptors enter Wednesday’s game as 4.5-point road underdogs, returning a 2.43x payout on PrizePicks Team Picks if they win outright.

The Clippers are home favorites with a 1.56x payout if they win, via PrizePicks Team Picks, where you can earn money with your picks in 35 states.

  • Spread: Los Angeles Clippers -4.5
  • Over/Under: 227.5
  • Game Winner Payout: Raptors 2.43x | Clippers 1.56x

Team Picks data is live at the time of writing and is subject to change.


Raptors vs. Clippers Injury Report

Let’s dive into the full Raptors vs. Clippers injury report for Wednesday, via NBA.com.

Toronto Raptors Injury Report

  • SF Brandon Ingram (heel): Questionable
  • C Jakob Poeltl (back): Questionable
  • PG Immanuel Quickley (foot): Questionable

Los Angeles Clippers Injury Report

  • F Kawhi Leonard (ankle): Questionable
  • SF-SG Jordan Miller (back): Questionable

Raptors vs. Clippers Prediction on Spread – 3/25/26

Here are the key stats to know before locking in your Raptors vs. Clippers prediction on spread for Wednesday, March 25 on PrizePicks.

  • This season, the Clippers are 16-22 against the spread as favorites. The Raptors are an impressive 17-13 ATS as underdogs. 
  • Toronto boasts a solidly efficient offense at a league-average 15th in effective field goal percentage (54.2%) but leads the sport in fastbreak PPG (18.1).
  • On the defensive end, the Raptors sit ninth in scoring (112.3 PPG), second in fastbreak scoring (12.8 PPG), and eighth in the paint (47.4 PPG).
  • The Clippers’ offense plays at a slow pace but generates quality looks, ranking third in points per shot at 1.193. 
  • On the other side of the ball, Los Angeles struggles to defend the 3-point shot (36.7%, 25th) this season and ranks 19th in defensive rating in the last 10 games.

Raptors vs. Clippers Picks for PrizePicks Today: 3/25/26

Here are three top Raptors vs. Clippers picks to target for Wednesday, March 25 on PrizePicks. Player stat projections via PrizePicks are headlined by PF Scottie Barnes, SF Brandon Ingram, and PG Darius Garland.

Raptors PF Scottie Barnes vs. Clippers Projection: 29.5 Pts + Rebs + Asts

  • On the year, Barnes averages 31.8 combined points, rebounds, and assists. 
  • Barnes is shooting a career-high 50.4% from the field, largely thanks to making 71.8% of his shots from 0-3 feet, 47.7% from 10-16 feet, and 47.1% from 16 feet to the 3-point line.
  • This is the second time in three years Barnes has posted a total rebounding rate of 13.0%, tying his personal best from 2023-24. 
  • Via NBA RAPM, Barnes averages 3.0 potential assists per minute on-ball.

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Raptors SF Brandon Ingram vs. Clippers Projection: 25.5 Pts + Rebs

  • Ingram puts up 27.2 points and rebounds per game this season. That figure is 25.8 in 20 contests since the start of February. 
  • After shooting an ugly 28.2% from deep in November, B.I. has canned a scorching 40.3% of his 3-point tries on 4.8 attempts each night.
  • Ingram is an absolute assassin inside the arc, ranking in the 98th percentile in 2-point shots per 100 possessions (17.7). 
  • Per databallr, Ingram’s 14.3% defensive rebounding rate puts him in the 92nd percentile.

Clippers PG Darius Garland vs. Raptors Projection: 26.5 Pts + Asts

  • In 10 outings as a Clipper, Garland averages 27.7 points and assists on a nightly basis.
  • Garland is on a hot streak from beyond the arc, making 50.7% of his 3-pointers in Los Angeles.
  • The Raptors surrender 26.07 PPG to the PG position, according to FantasyPros, the seventh-highest mark in the sport. 
  • Garland spends 37.2% of his time on-ball and nets 19.9 potential assists per 100. 

Make Raptors vs. Clippers Picks on PrizePicks

Raptors vs. Clippers picks for Wednesday night hoops aren’t the only avenue hoops fans have to getting in on the daily NBA action.

You can make your picks on PrizePicks and PrizePicks Team Picks and earn real money. Just pick players, predict More or Less on their projected stats, and cash in if you’re correct. With Team Picks, make predictions on winners, spreads, and over/unders, now available in 35 states

Stick around with the Playbook for continued NBA predictions, picks, and news.

Get in the game! Sign up for PrizePicks and cash in on your sports predictions. Play $5 and get $50 instantly in Lineups with promo code PLAYBOOK.

Team Picks and Culture Picks are event contracts offered by Performance Predictions II, LLC d/b/a PrizePicks Predict, a CFTC-registered FCM and NFA Member. All event contract customers must be U.S. residents and 18+. Some event contracts may not be available in every state. Event contract trading carries significant risk and is not appropriate for everyone. No guarantee against loss is offered. Past results are not necessarily indicative of future results. Void where prohibited by law. Restrictions apply. For full terms of service see prizepicks.com/predict-regulatory. Team and Culture Pick Early Payouts subject to market liquidity. The content provided is for informational and educational purposes only and does not constitute investment advice, or a recommendation to trade any commodity interest.

about the author

Jordan Foote is a seasoned sports writer with years of experience covering the NFL, NBA and MLB for multiple outlets. He is a Baker University alumnus, earning his degree in Mass Media with an emphasis in sports journalism. Foote was born and raised in Kansas City, where he still resides to this day.

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