The Detroit Pistons vs. Cleveland Cavaliers game is set to tip off at 8:00 p.m. ET on Monday, May 11, with the Cavaliers entering as 3.5-point favorites on the spread, via PrizePicks.
After dropping the opening two games, the Cavaliers were able to bounce back at home in Game 3 with an impressive performance. Can Cleveland keep it up in Game 4 on Monday?
Below, we'll break down our Pistons vs. Cavaliers prediction and picks for Monday’s NBA Playoff Game 4, including the spread, over/under, and key player picks for PrizePicks.
Make your Pistons vs. Cavaliers prediction on PrizePicks for today’s Game 4.
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Pistons vs. Cavaliers Prediction, Spread, Over/Under for Game 4 – Monday, May 11
The Pistons defended their home floor with two convincing victories to begin the Eastern Conference semifinals. However, the Cavaliers did have considerable success on their home court in Game 3.
Cleveland just came away with a 116-109 win against Detroit to cut the series deficit to 2-1. SG Donovan Mitchell exploded for 35 points on 13-of-24 shooting in what was one of his most productive performances of the 2026 postseason.
The Cavaliers shot a scalding 58.1% from the field while also knocking down 37.5% (12-of-32) of their shots from 3-point land. Defensively, Cleveland was able to limit Detroit’s effectiveness from beyond the arc throughout Game 3.
Cleveland now aims to even the series on its home court, which has been a key theme so far. If the Cavaliers can continue to excel from the perimeter, another victory could be within their grasp.
Pistons vs. Cavaliers Spread, Over/Under for Game 4 – Monday, May 11
The Cavaliers enter Monday’s game as 3.5-point home favorites against the Pistons, returning a 1.58x payout if they win outright, via PrizePicks Team Picks.
Here are the full payouts for the Pistons vs. Cavaliers game on PrizePicks.
- Spread: Cleveland Cavaliers -3.5 (1.85x payout)
- Over/Under: 214.5 (1.92x payout on Over)
- Game Winner Payout: Pistons 2.27x | Cavaliers 1.58x
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Team Picks data is live at the time of writing and is subject to change.
Detroit Pistons vs. Cleveland Cavaliers Timeline
Here is the full Pistons vs. Cavaliers timeline, including the playoff series game-by-game and recent matchup history.
All-Time: Pistons, 143-126
Regular Season: Tied 2-2
Series: Pistons, 2-1
Pistons vs. Cavaliers Eastern Conference Semifinals Timeline, Schedule for 2026 NBA Playoffs
- Game 1: Pistons 111, Cavaliers 101
- Game 2: Pistons 107, Cavaliers 97
- Game 3: Cavaliers 116, Pistons 109
- Game 4: Monday, May 11, 8:00 p.m. ET in Cleveland
- Game 5: Wednesday, May 13, TBD in Detroit
- Games 6-7 if necessary
Pistons vs. Cavaliers Prediction on Over/Under for Game 4
Here are the key game stats and trends behind our Pistons vs. Cavaliers prediction on the over/under for Monday, May 11.
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- The under is 2-1 in the Eastern Conference semifinal series between the Pistons and Cavaliers.
- The Pistons have allowed the fewest PPG (99.8) in the NBA Playoffs up to this point. Detroit also holds its opponents to 42.1% shooting from the field, ranking second in the playoff field.
- Detroit has attempted the second-fewest shots from beyond the arc (28.7) among postseason teams.
- The Cavaliers are shooting just 33.6% from deep this postseason, which ranks 11th.
- Per NBA Advanced Stats, the Pistons are 13th in assist/turnover ratio (1.38), while the Cavaliers are dead last (1.29).
- The under is 7-3 in the last 10 meetings between Cleveland and Detroit.
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Pistons vs. Cavaliers Picks, Player Stats for PrizePicks – 5/11/26
Here are the top Pistons vs. Cavaliers picks to target in the NBA Playoffs on PrizePicks for Monday, May 11. Today’s NBA picks for PrizePicks include PF Tobias Harris and Cavaliers PF Evan Mobley.
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Pistons PF Tobias Harris vs. Cavaliers Projection: 25.5 Pts + Rebs
- Harris has averaged a combined 27.4 points and rebounds in three games during the Eastern Conference semifinals.
- The Pistons’ standout forward has registered at least 26 points and rebounds in nine of his 10 NBA Playoff games in 2026, including in all three contests in this series.
- Harris is shooting an impressive 45.5% from beyond the arc in the second round, knocking down multiple treys twice.
- According to NBA Advanced Stats, Harris has secured 29.9% of his contested rebound opportunities this postseason.
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Cavaliers PF Evan Mobley vs. Pistons Projection: 15.5 Points
- Mobley has scored 14 or fewer points in all three games vs. the Pistons in this series.
- The Cavaliers’ big man has only scored at least 16 points in four of his 10 games this postseason.
- Mobley is averaging just 9.0 field goal attempts in the series, down from 11.6 per contest vs. the Toronto Raptors in the first round of the NBA Playoffs.
- According to databallr, the former lottery pick is shooting 29.7% from 3-point range this season, which ranks in just the 55th percentile.
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NBA Playoffs Live Picks: Pistons vs. Cavaliers on PrizePicks for Game 4
Here are some in-game angles to target for your Pistons vs. Cavaliers live picks in tonight’s game.
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- The Cavaliers come out of the locker room strong in the second half, averaging 31.0 PPG this season (second in the NBA). Meanwhile, the Pistons rack up 28.5 PPG in the third quarter, 21st in the league.
- Cleveland and Detroit haven’t run uptempo offenses throughout the NBA Playoffs. According to NBA Advanced Stats, the Cavaliers own the ninth-best pace of play (96.20) among playoff teams, while the Pistons come in 12th with a 95.00 pace.
- Pistons PG Cade Cunningham has been more productive offensively on the road this season. In road contests, Cunningham has averaged 25.2 PPG and shot 37.0% from beyond the arc, compared to 22.4 PPG and 30.0% at home.
- The Pistons score just 28.1% of their points from 3-point range, second-to-last in the league. In the postseason, Detroit has connected on just 10.1 trey-balls per contest, 14th among playoff teams.
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It’s proved to be a defensive battle between the Cavaliers and Pistons throughout the Eastern Conference semifinals thus far. As a result, it’s possible that another low-scoring affair could be on tap in Game 4.
Don’t wait until tip-off — make your Pistons vs. Cavaliers picks on PrizePicks now and earn real money if you’re right.
Pick players, predict More or Less on their stats, and cash in if you’re right. With Team Picks, you can make predictions on game winners, spreads, and over/unders, now available in 35 states.
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