Patriots vs. Browns Prediction, Spread, NFL Preseason Picks – Thursday, August 27

Another week, another stretch of NFL preseason action to enjoy. Thursday marks the beginning of the end for several teams, including the New England Patriots and Cleveland Browns clashing in both clubs’ final outing before Week 1 of the regular season.

Ahead of the 8 p.m. ET bout on Prime Video, New England is favored on the road and returns a 1.66x payout on PrizePicks Team Picks with an outright victory. Can the reigning AFC champions triumph in hostile territory, or will the Dawg Pound reign supreme? 

Below, we'll break down our Patriots vs. Browns prediction and picks for Thursday’s NFL preseason game, including the spread, over/under, and key player picks for PrizePicks.

Make your Patriots vs. Browns prediction and picks on PrizePicks now.

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Patriots vs. Browns Prediction, Spread, Over/Under for NFL Preseason – Thursday, August 27

The Patriots enter Thursday’s game as 2.5-point road favorites against the Browns, returning a 1.66x payout on PrizePicks Team Picks if they win outright.

Here are the full payouts for the Patriots vs. Browns NFL preseason game on PrizePicks.

Make your Patriots vs. Browns prediction on spread or over/under on PrizePicks Team Picks — available in 36 states!

Payouts show potential returns on correct Team Picks predictions. A 2x payout returns $200 on a $100 entry. Lower multipliers reflect outcomes users are picking as more likely. Payouts are live as of writing and subject to change.

Patriots vs. Browns Prediction on Spread for NFL Preseason – 8/27/26

Here are the key game stats and trends behind our Patriots vs. Browns prediction on the spread for Thursday, August 27’s game. 

• New England has performed much better this preseason, posting a 1-0-1 record with a +3 point differential. Cleveland, meanwhile, followed up its undefeated 2025 preseason slate by failing to win a game thus far this month with a -48 PD. 
• Let’s face it: Cleveland’s roster simply isn’t up to snuff with the rest of the NFL. It ranked 30th of 32 teams in FTN’s DVOA metric a year ago and is now on a collision course with the ninth-ranked squad of 2025-26. 
• The Browns’ defense has fallen completely flat in the second half of these two preseason games, surrendering 17 points to the Buffalo Bills and 24 to the Chicago Bears. 
• New England already had a clear QB advantage in this one, and that remains the case even with both sides mutually agreeing to sit their starters. 
• The turnover battle heavily favors the visitors, who have generated 5 takeaways in August. The hosts, meanwhile, have coughed up the ball the same number of times. 
• HC Mike Vrabel’s group is a perfect 6-0 in its last six meetings with the Browns and has won back-to-back trips to Cleveland. 

Lock in your Patriots vs. Browns prediction on PrizePicks before tonight’s NFL preseason game.

Patriots vs. Browns Picks, Player Stats for NFL Preseason on PrizePicks: 8/27/26

Here are the top Patriots vs. Browns picks to target on Thursday, August 27. Today’s NFL preseason picks for PrizePicks include K Andy Borregales, WR Efton Chism III, and QB Dillon Gabriel. 

Patriots K Andy Borregales vs. Browns: 1.5 FG Made

• Borregales went just 2-for-5 in the preseason opener against the Indianapolis Colts, but that pair of made field goals still cleared Thursday’s projection. 
• The veteran placekicker had starting long snapper Julian Ashby (ankle) back for the Philadelphia Eagles matchup and drilled his long field goal try from 41 yards, also going 3-for-3 on extra points. 
• The former Miami standout was a long-range sniper in his debut regular season, converting on 4 of 4 tries from 50+ yards.
• Chicago and Buffalo combined to attempt 4 field goals in the Browns’ first two preseason contests. 

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Patriots WR Efton Chism III vs. Browns: 21.5 Rec Yards

• Chism played 34 snaps in New England’s opener against Philly, then went on to log 32 against the Indianapolis Colts. The absence of projected starters could only work in his favor here. 
• The Eastern Washington product has hauled in all 7 of his targets this preseason, producing 65 yards in the process. 
• Albeit in a small sample size, Chism ran 34 routes as a rookie and notched a staggering 2.21 yards per route mark, via SumerSports. 
• Despite being smaller in stature, Chism isn’t confined to the slot. Per Pro Football Focus, he spent 76.6% of his time out wide as a rookie, which could allow him to affect the game in multiple ways on Thursday. 

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Browns QB Dillon Gabriel vs. Patriots: 95.5 Pass Yards

• Gabriel has yet to deliver any signature moments this preseason, going 5-of-8 for 23 yards and an INT vs. Chicago and not completing his lone pass attempt vs. Buffalo.
• According to RBSDM, among 41 QBs with as many plays as him last year, Gabriel ranked 39th in adjusted EPA/play (-0.114) and 40th in success rate (35.2%). 
• New England’s dropback EPA/play allowed of -0.018 was good for 10th during the regular season.
• Don’t necessarily expect Gabriel to air it out on Thursday. Out of 45 QBs to log 100+ plays in 2025, his 5.96-yard average depth of target was higher than only New York Jets signal-caller Brady Cook.

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Make Patriots vs. Browns Picks for NFL Preseason on PrizePicks

This battle may seem lopsided on paper, but the beauty of preseason football is that surprises are oftentimes right around the corner. As New England and Cleveland’s organizational depth pieces duke it out for spots on the 53-man roster, there might just be some competitive football taking place. 

Don’t wait until kickoff for more preseason football — make your Patriots vs. Browns picks on PrizePicks now and earn real money if you’re right.

Pick NFL players, predict More or Less on their stats, and cash in if you’re right. With Team Picks, you can make predictions on preseason NFL game winners, spreads, over/unders, and futures, now available in 36 states.

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