Oklahoma vs. #2 Georgia Prediction, Spread, NCAAF Picks Today – 9/26/26

The #2 Georgia Bulldogs (3-0) play host to the Oklahoma Sooners (2-1) for a 3:30 p.m. ET kickoff on ESPN. Elevated by an average margin of +46.0 points per game, Georgia is a 13.5-point favorite on the spread vs. Oklahoma, via PrizePicks.

Following Week 2’s 17-10 loss vs. Michigan, Oklahoma struggled with a 14-6 win over New Mexico last week. Meanwhile, the Dawgs have been a buzzsaw, opening SEC play with a 45-17 win as 24.5-point favorites on the road vs. Arkansas last weekend. 

Below, we’ll dive into Saturday’s college football game and provide an Oklahoma vs. Georgia prediction and player picks for PrizePicks.

Make your Oklahoma vs. Georgia picks on PrizePicks now! 

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Oklahoma vs. #2 Georgia Prediction, Spread, Over/Under for Saturday, September 26

If you like defense, this could be the matchup for you. According to Game on Paper, Oklahoma allows -0.23 EPA per play (96th percentile) while Georgia yields -0.08 EPA per play (83rd percentile). That’s translated to the Sooners giving up 7.7 PPG (96th percentile) and 3.5 yards per play (97th percentile), compared to the Dawgs’ 18.5 PPG (77th percentile) and 3.7 yards per play (93rd percentile).

Offense is where we see a major difference, proven by OU’s 42.6% success rate (37th percentile). After totaling only 10 points, 5.7 yards per passing attempt, and 3.4 yards per carry vs. Michigan, the Sooners were perhaps even worse last week by totaling 14 points and 1.9 yards per rushing attempt vs. New Mexico.

UGA brings a much more reliable offense, sporting a 56.0% success rate (94th percentile), including 55.1% in the passing game (88th percentile) and 56.7% on the ground (86th percentile). Against Arkansas, the Bulldogs racked up 45 points, 464 yards, 10.0 yards per passing attempt, and 6.0 yards per carry.   

Several key injuries are storylines headed into this matchup. 

For Oklahoma, DT David Stone, who is 16th overall on NFL Mock Draft Database’s 2027 NFL Draft consensus big board, is questionable with a knee injury. Sooners OT Michael Fasusi and WR Trell Harris are out. 

Georgia starting RB Nate Frazier is questionable, and WR Isiah Canion is questionable after missing last week’s game. 

Ultimately, injuries could have a major impact on Georgia’s ability to run the ball. The Bulldogs carry a 61.1% rush-play rate (80th percentile), and Frazier leads the team with 202 rushing yards. 

Stone is one of the best defensive tackles in college football, fueling OU’s rush defense that allows only 2.8 yards per carry (87th percentile) and 2.3 line yards per carry (86th percentile), measured by yards per rush allowed at the line of scrimmage, per Fourth and Short.

Oklahoma vs. Georgia Spread, Over/Under, Payouts – Saturday, September 26

After being favored by 24.5 points last week, Georgia is once again a heavy favorite in SEC play, listed as a 13.5-point favorite on PrizePicks.

Here are the full payouts for Oklahoma vs. Georgia on PrizePicks, including winner payouts, the spread, and over/under.

Make your Oklahoma vs. Georgia prediction on the spread on PrizePicks!

PrizePicks data is live at the time of writing and is subject to change.

Oklahoma vs. Georgia Prediction on Spread – 9/26/26

As mentioned, injuries could carry plenty of weight in deciding the spread. For Oklahoma, DT David Stone may need to play to keep this close. Even if he does suit up, the Sooners have still generated an underwhelming 21.1% stuff rate against the run (55th percentile).

Focusing on Georgia’s run game, the offensive line has paved the way by allowing only an 11.9% stuff rate (86th percentile) while generating 3.9 line yards per carry (96th percentile). 

No Nate Frazier would be a blow, as the RB has 5.29 yards after contact per carry, per Pro Football Focus. However, QB Gunner Stockton is a threat with his legs, including last week’s 7 carries for 97 rushing yards (13.9 YPC). 

Oklahoma’s offensive line produces only 2.6 line yards per carry (14th percentile) and allows a 26.0% stuff rate (third percentile). The Dawgs’ rush defense is elite across the board, allowing a 32.0% success rate (96th percentile).

In a potential defensive battle, the Sooners could be at a major disadvantage if they’re losing the trenches in the run game. Further adding to OU’s troubles, QB John Mateer has struggled with 3 INTs over his last two games, compiling 4 turnover-worthy plays in the split.

UGA’s defense has a nose for the ball by forcing 2.5 takeaways per contest (95th percentile), and the Bulldogs are likely licking their chops considering Oklahoma’s 3 turnovers last week.

Furthermore, the Bulldogs’ offense usually stays on schedule with a 5.10-yard average third-down distance (97th percentile). In comparison, OU carries a 6.62 average third-down distance (66th percentile). 

Georgia is 3-0 against the spread (ATS) this season, while the Sooners have failed to cover back-to-back games. If Oklahoma is losing the turnover and third-down battles, too, the Dawgs could keep rolling at home.

Lock in your Oklahoma vs. Georgia prediction on PrizePicks before kickoff!

Oklahoma vs. Georgia Picks, Player Stats for PrizePicks – 9/26/26

Saturday’s top Oklahoma vs. Georgia picks to target on PrizePicks include WR Isaiah Sategna III and RB Nate Frazier.

Oklahoma WR Isaiah Sategna III vs. Georgia: 49.5 Receiving Yards

• While QB John Mateer has stumbled at times, Isaiah Sategna III has found paths to success, including 76 receiving yards in Week 1 and 101 receiving yards last week.
• The Sooners carry a low 45.65% pass-play rate (47th percentile) with 26.0 passing attempts per game (36th percentile), but that volume could rise from a negative game script on Saturday.
• If Oklahoma is in a big deficit, Sategna may be the one to benefit with his team-best 7.0 targets and 4.0 receptions per game.
• Further, the senior wideout is a big-play threat with 15.5 yards per reception and a healthy 11.4 average depth of target (aDOT).
• Georgia ranks 30th nationally in pass success rate allowed and 32nd in pass explosiveness allowed, perhaps showing an angle for OU to move the rock.

Add Isaiah Sategna III to your PrizePicks lineup now.

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Georgia RB Nate Frazier vs. Oklahoma: 60.5 Rush Yards

• Nate Frazier is an excellent talent who could find himself drafted in the second or third round of the 2027 NFL Draft. If he keeps at his current pace, including 8.4 yards per carry, Frazier could even flirt with a first-round grade.
• Of course, much of this hinges on if he plays with a questionable status. When active, Frazier has posted 67.3 rushing yards per game.
• After recording only 4 and 6 rushing attempts in his first two games. Georgia upped his workload to 14 carries last week. As mentioned, the offense as a whole has a high rush-play rate, likely meaning a busy season ahead for the Dawgs’ RB1.
• Oklahoma ranks 134 out of 138 FBS teams for rush explosiveness allowed. That should be setting off the alarms against Frazier, who’s been clocked at nearly 20.0 mph and had at least a 19-yard carry in all three games this season.  

Pick Nate Frazier + Georgia to win on PrizePicks.

Make Oklahoma vs. Georgia Picks on PrizePicks

Following a rough non-conference slate, Oklahoma begins treacherous SEC play against perhaps the best the conference has to offer. Will the Sooners find a way to keep in close against Georgia in Athens?

Don’t wait until kickoff — make your Oklahoma vs. Georgia picks on PrizePicks now. Just pick your players, predict More or Less on their stats, and cash in on your predictions if you’re right. With Team Picks, you can make predictions on game winners, spreads, and over/unders — now available in 36 states!

Keep it here with the Playbook for continued CFB picks, predictions, futures, and more all the way through the College Football Playoff.