NBA Picks Today: Best Pacers vs. Cavaliers Picks for Game 5 – 5/13/25

Tuesday’s NBA Playoffs slate brings us the top-seeded Cavaliers facing elimination at home as the Pacers hold a 3-1 series lead. 

We’ll give you the top Cavaliers vs. Pacers picks and predictions for tonight’s Game 5 on PrizePicks, including projections for Donovan Mitchell and Pascal Siakam.

The Pacers are looking to complete the series upset as they take on the Cavaliers at 7 p.m. ET on TNT. Meanwhile, the Cavaliers – who have been banged up – have had a few more days to get healthy.  

Combine these picks with the Taco Tuesday discounted projections on PrizePicks to win real cash, including Pacers PG Tyrese Haliburton points, discounted to 13.5 from 17.

PrizePicks is the easiest way to cash in on your NBA Playoffs takes. Just pick More or Less on player stats across the NBA — from points to assists to combos — and lock in your Lineup. New to PrizePicks? Claim your $50 bonus and get started here.

Let’s break down some of the best NBA picks to target in the Pacers vs. Cavaliers game in the NBA Playoffs on PrizePicks.

Best Pacers vs. Cavaliers Picks for Game 5

Here are three of the top Pacers-Cavaliers picks in Game 5 for Tuesday, May 13, on PrizePicks. Click each pick to read more.

• Cavaliers SG Donovan Mitchell — 28.5 Points
• Cavaliers SF De’Andre Hunter — 2.5 Rebounds (Goblin)
• Pacers PF Pascal Siakam — 17.5 Points

Cavs SG Donovan Mitchell — 27.5 Points

• Cavs SG Donovan Mitchell cleared this projection in three of four games in this series vs. the Pacers.
• He has a great history against the Pacers by scoring over 30 points in seven of the last nine games against Indiana, dating back to 2023.
• Mitchell has scored 30 points or more in all seven of those games. 
• Mitchell is averaging 27.0 points per game this season against the Pacers, which is higher than his 24.0 overall average this season.
• Mitchell has tried to carry this team throughout the series by taking at least 29 shots in three of four games.
• The Pacers are playing at the second-fastest pace (99.19) of the remaining eight teams in the Playoffs.

Cavaliers SF De’Andre Hunter — 2.5 Rebounds (Goblin)

• Cavaliers SF De’Andre Hunter has secured this rebound projection in both games since returning to the lineup in Game 3.
• This is despite playing under 25 minutes in both games as he returns from injury. 
• Hunter has cleared this projection in six of the last seven games against Indiana.Hunter has at least four rebounds in every game vs Indiana this year.
• Hunter has averaged 27.9 minutes per game this season and 30.6 minutes against Indiana.
• The Pacers have struggled to defend the boards, as their 44.6 rebounds allowed per game is 12th in the playoffs, and they were 20th in the regular season in rebounds allowed to forwards.

Pacers PF Pascal Siakam — 17.5 Points 

• Pacers PF Pascal Siakam got back to form with 21 points in the Game 4 win.
• He’s had a history of success against Cleveland, scoring 18 or more points in eight of his last 11 games.
• Siakam has exceeded this projection in 64.3% of road games this season.
• The Cavaliers are allowing opponents to shoot 47.5% from the floor, the worst percentage among the teams remaining in the playoffs.
• In the last two blowouts, Siakam played under 30 minutes. Previously, he played at least 30 minutes in three-straight games.

Make Cavaliers vs. Pacers Picks on PrizePicks

We have an exciting playoff matchup on Tuesday night in the Eastern Conference with the Cavaliers trying to hold off elimination against the Pacers.

With the NBA Playoffs heating up, there’s never been a better time to get in on the action with PrizePicks. There are plenty of NBA DFS options to pick for your PrizePicks Lineups tonight, including players like Pascal Siakam and Donovan Mitchell. 

Just pick More or Less at least two NBA player stat projections to build your Lineup on PrizePicks. Create your account to get $50 in bonus funds when you play your first $5 Lineup.

Check out the Playbook daily for more NBA DFS picks all the way through the NBA Playoffs.