#18 LSU vs. Auburn Prediction, Spread, NCAAF Picks – Saturday, October 24

Week 8 of the college football season is upon us, and one of the marquee matchups features #18 LSU traveling to face Auburn on Saturday, October 24, at 12:00 p.m. ET. Ahead of Saturday’s SEC clash on ABC, LSU is favored on the road, with a 1.33x payout to secure a win on PrizePicks.

LSU cruised to a 31-0 victory over Mississippi State in Week 7, helping head coach Lane Kiffin’s squad bounce back from an upset loss to Kentucky in Week 6. On the other side, Auburn had one of the biggest upsets in its program’s history in Week 7, slaying #1 Georgia 27-24 as 19.5-point underdogs on the road.

Below, we'll break down our LSU vs. Auburn prediction and picks for Saturday’s college football game, including the spread, over/under, and key player picks on PrizePicks.

Make your LSU vs. Auburn prediction on PrizePicks now!

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#18 LSU vs. Auburn Prediction, Spread, Over/Under – Saturday, October 24

LSU enters Saturday’s game as a 7.5-point road favorite against Auburn, returning a 1.33x payout on PrizePicks if it wins outright.

Here are the full payouts for the LSU vs. Auburn game on PrizePicks. PrizePicks data is live at the time of writing and is subject to change.

Make your LSU vs. Auburn prediction on the over/under on PrizePicks.

Stats used in this article are from Game on Paper, PFF, and Two Deep unless stated otherwise.

Despite being a ranked team entering Week 8, it’s safe to say LSU isn’t content with how things are going in Kiffin’s first year at the helm. The Bayou Bengals are 2-2 in the SEC, losing to #7 Ole Miss (Kiffin’s former team) and #12 Kentucky in conference play.

Arizona State transfer QB Sam Leavitt has struggled with turnovers and sacks in his debut campaign with LSU. Among 64 QBs with 200 or more dropbacks this season, Leavitt is tied for the most INTs (8) and is 24th in pressure-to-sack rate (18.7%).

Currently, ‘Yes’ for LSU to make the College Football Playoffs carries a 2.43x payout on PrizePicks, while ‘No’ has a 1.51x payout.

Upon reuniting with head coach Alex Golesh at Auburn, USF transfer QB Byrum Brown used his legs to take down top-ranked Georgia, carrying the ball a season-high 26 times for 115 yards and a score. Brown is tied for the fourth-most INTs (7) while having the second-highest pressure-to-sack rate (32.1%) from the same sample mentioned before.

Auburn is also 2-2 against SEC opponents this season, losing to #11 Tennessee and #20 Florida. Across the team’s first six games in 2026, Auburn is in the 26th percentile in EPA/pass (0.01) and 74th percentile in EPA/rush (0.12).

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LSU vs. Auburn Prediction on the Over/Under – 10/24/26

Here are the key game stats and trends behind our LSU vs. Auburn prediction on the total for Saturday, October 24’s game. 

• LSU’s defense is in the 99th percentile in EPA/pass (-0.29) and the 66th percentile in EPA/rush allowed (-0.01) this season.
• Aside from their losses to Ole Miss and Kentucky, the Bayou Bengals have allowed 14 or fewer points in their other five games.
• Meanwhile, Auburn’s defense resides in the 69th percentile in EPA/pass (-0.03) and the 54th percentile in EPA/rush allowed (0.02).
• Over its first four conference games in 2026, LSU is 1-3 to the over.
• As for Auburn, it is only 2-4 to the over in its six games this year.
• Across the last 10 head-to-head meetings between LSU and Auburn, the over is 3-7.

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LSU vs. Auburn Picks, Player Stats for PrizePicks: 10/24/26

Here are the top LSU vs. Auburn picks to target on Saturday, October 24. Today’s college football picks for PrizePicks include Jackson Harris and Chas Nimrod.

LSU WR Jackson Harris vs. Auburn: 49.5 Receiving Yards

• Harris has logged 54 or more receiving yards in three of his last four games.
• All three of those instances came against SEC opponents.
• Of the three WRs on LSU who have played 100 passing-down snaps this season, Harris has the most yards per reception (16.9) and yards per route run (2.53).
• Auburn’s defense is in just the 45th percentile in pass success rate (44.4%).

Add Jackson Harris to your PrizePicks lineup now.

Auburn WR Chas Nimrod vs. LSU: 3.5 Receptions

• Nimrod has posted 4 or more receptions in four of his last five games this season.
• Among the three WRs on Auburn to have 100-plus passing-down snaps, Nimrod has the second-most targets (47) and highest catch rate (66.0%).
• Auburn will need to methodically move the ball through the air against an LSU defense that is in the 96th percentile in pass success rate allowed (35.1%).
• Nimrod has just an 8.7-yard average depth of target this year.

Add Chas Nimrod to your PrizePicks lineup now.

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Make LSU vs. Auburn Picks on PrizePicks

LSU and Auburn are both looking to avoid suffering its third loss in the SEC this season on Saturday. With each team potentially playing more conservatively to avoid making plays to lose the game, points could be tougher to come by — especially against above-average defenses.

Don’t wait until kickoff — make your LSU vs. Auburn picks on PrizePicks now and earn real money if you’re right.

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