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On Wednesday’s Champions League slate, Liverpool will square off against Atlético Madrid at 3 p.m. ET. As the home team, Liverpool enters the September 9 match as a massive favorite, returning a 1.66x payout on PrizePicks.
Wednesday’s match at Anfield pits two clubs that aren’t strangers to competing in the UCL in recent years against each other. Liverpool is the most successful English club in the Champions League with six wins in the competition.
Meanwhile, Atlético Madrid is still seeking their first UCL trophy, though they’ve advanced to the Round of 16 or further in three straight Champions League tournaments.
Below, we’ll discuss our Liverpool vs. Atlético prediction and picks for Wednesday’s Champions League showdown.
Make your Liverpool vs. Atlético prediction on PrizePicks for today’s match.
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Liverpool vs. Atlético Prediction, Picks for Champions League – Wednesday, September 9
How to watch Liverpool vs. Atlético: Paramount+ (English) / UniMás (Spanish)
Kick-off time: 3 p.m. ET
Venue: Anfield, Liverpool, England
Entering the 2026-27 campaign, Liverpool has had their third different manager since 2024, with Andoni Iraola taking the job this year. Iraola and the Reds have begun this year’s Premier League season sixth in the table with a win and two draws.
Liverpool’s most recent EPL match was a 2-0 victory over Ipswich Town, led by ST Alexander Isak supplying a brace. While the Reds have spent loads of money on their attack, Iraola would love to see his new-look back line of CB Virgil van Dijk, CB Jérémy Jacquet, RB Ronald Araújo, and LB Milos Kerkez show more chemistry.
Atlético Madrid also finds themselves in sixth place in their domestic league standings, logging a 2-1-1 record to kickstart the 2026-27 La Liga season. Manager Diego Simeone’s side lost their most recent match, falling 3-0 to Athletic Club.
Simeone has plenty of experience balancing the La Liga and Champions League schedules during his tenure with Atlético since 2011. However, it’s been a slow start on the attack for Simeone’s side, as they’ve mustered the third-fewest xG (3.7) in La Liga so far, per FotMob.
Ahead of Wednesday’s game, Liverpool returns the seventh-lowest payout to win the Champions League (14.28x) on PrizePicks. Atlético Madrid is tied with Manchester United and Inter for the eighth-lowest payout to win the UCL (22.22x).
Liverpool vs. Atlético Spread, Total Goals, Payouts – Wednesday, September 9
Liverpool enters Wednesday’s Champions League match as home favorites, returning a 1.66x payout ($100 entry pays out $166) on PrizePicks if they win outright. A tie also returns a 3.7x payout.
Here are the full payouts for the Liverpool vs. Atlético match on PrizePicks.
Play the Liverpool vs. Atlético spread or total goals on PrizePicks Team Picks!
PrizePicks payouts are live at the time of writing and are subject to change. Does not include extra time or penalties.
Liverpool vs. Atlético Prediction on Total Goals – 9/9/26
Here are some stats to know to help you make your Liverpool vs. Atlético prediction on total goals scored for Wednesday, September 9. Check out more of our soccer picks and predictions on Playbook.
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- To begin the Iraola era at Liverpool, the Reds have had at least 3 total goals scored in two of their first three matches.
- Atlético Madrid has seen at least 3 total goals scored in each of their last three La Liga matches this season.
- Liverpool and Atlético have faced each other five times in the Champions League since 2020, and there have been 5+ goals scored in three of the last four meetings.
- Not only has Liverpool scored multiple goals in each of their first three EPL matches in 2026, but Atlético has tallied multiple goals in three of their first four La Liga games.
- Across their first three EPL games this year, Liverpool is tied for the second-most shots on target (18) in the Premier League.
- The Reds also have both the fifth-highest pass success rate (87.6%) and final third pass success rate (76.7%), per Opta Analyst.
Liverpool vs. Atlético Projected Lineups
Here are the projected Liverpool vs. Atlético lineups for today's Champions League match. Lineups are not official.
Liverpool Lineup vs. Atlético: Projected 4-2-3-1
- Goalkeeper: Alisson Becker
- Defense: Milos Kerkez, Virgil van Dijk, Jérémy Jacquet, Jeremie Frimpong
- Midfield: Dominik Szoboszlai, Alexis Mac Allister, Florian Wirtz
- Forwards: Bradley Barcola, Alexander Isak, Cody Gakpo
Atlético Lineup vs. Liverpool: Projected 4-4-2
- Goalkeeper: Jan Oblak
- Defense: Alejandro Grimaldo, Dávid Hancko, Marc Pubill, Marcos Llorente
- Midfield: Álex Baena, Morten Hjulmand, Pablo Barrios, Giuliano Simeone
- Forwards: Lee Kang-In, Ademola Lookman
Liverpool vs. Atlético Picks, Player Stats for PrizePicks for Champions League: 9/9/26
Here are Liverpool vs. Atlético picks to target on Wednesday, September 9. Today’s UCL picks for PrizePicks include Dominik Szoboszlai and Pablo Barrios.
Liverpool CM Dominik Szoboszlai vs. Atlético: 2 Shots
- Szoboszlai has taken 3 shots in each of Liverpool’s first three EPL games this season.
- Only Isak has more shots per 90 minutes (3.3) on the Reds than Szoboszlai to begin the 2026-27 Premier League campaign.
- Among all the talent Liverpool possesses, Szoboszlai handles the majority of the team’s free kicks.
Add Dominik Szoboszlai to your PrizePicks lineup now.
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Atlético CM Pablo Barrios vs. Liverpool: 50.5 Passes Attempted
- Barrios has started in three of the first four La Liga matches for Atlético this season, and he’s played all 90 minutes in those starts.
- In all three of the matches, Barrios has made 58+ passes.
- Plus, Barrios has the second-most open-play passes (238) on Atlético Madrid’s roster this year.
- One of Atlético’s best chances of getting a result could feature them maintaining possession more and leaning on their midfield.
Add Pablo Barrios to your PrizePicks lineup now.
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Liverpool and Atlético Madrid have their sights on the UCL title in 2026-27 and would love to get this year’s competition started on the right foot. In both clubs’ Champions League opener, goals might be expected at Anfield.
Don’t wait until kick-off — you can make your Liverpool vs. Atlético picks for Tuesday’s Champions League match now on PrizePicks to earn real money.
Just pick your Champions League players, predict More or Less on their stats, and cash in if you’re right. With Team Picks, you can make predictions on a UCL match winner, total goals, and both teams to score — now available in 36 states.
Stay locked in with the Playbook for continued soccer and Champions League predictions, picks, and analysis.
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