Lakers vs. Knicks Prediction, Spread, Picks: Luka Doncic Magic Again?

Los Angeles Lakers PG Luka Doncic dribbles up the court against the New Orleans Pelicans.
AP Photo/Jessie Alcheh

Tonight at the world’s most famous arena, Madison Square Garden in New York City, the Los Angeles Lakers (29-18) face the New York Knicks (30-18) at 7 p.m. ET on NBC and Peacock.

The Knicks are coming in red hot with a five-game winning streak, currently second-best in the NBA. The Lakers are enjoying their annual Grammy road trip, winning four of their last six.

Let’s look at a Lakers vs. Knicks prediction and picks for Sunday's game. Make your predictions on PrizePicks and PrizePicks Team Picks and earn real money if you’re right, including on game winners, spreads, and totals.

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Lakers vs. Knicks Prediction, Spread, Over/Under

This is the first matchup between the Lakers and the Knicks in the 2025-26 season. New York has lost three straight to Los Angeles, with their last victory coming in 2023.

Lakers vs. Knicks Over/Under, Spread

The Knicks enter this matchup as 4.5-point favorites, returning a 1.49x payout on PrizePicks Team Picks if they win outright.

The Lakers are road underdogs with a 2.43x payout if they win, via PrizePicks Team Picks.

  • Spread: New York Knicks -4.5
  • Over/Under: 229.5
  • Game Winner Payout: Lakers 2.43x | Knicks 1.49x

Team Picks data is live at the time of writing and is subject to change.


Lakers vs. Knicks Injury Report

Let’s dive into the full Lakers vs. Knicks injury report for Sunday, via NBA.com.

Lakers Injury Report 

  • SG Bronny James (leg): Questionable
  • SG Austin Reaves (calf): Questionable

Knicks Injury Report 

  • G Miles McBride (ankle): OUT

Lakers vs. Knicks Prediction on Spread

Here are some facts and figures to get you set for Lakers vs. Knicks tonight, including insights on our Lakers vs. Knicks prediction.

  • The Lakers are 9-6 against Eastern Conference opponents.
  • The Knicks have 19 wins at home, the second-most in the NBA.
  • New York ranks sixth in points scored per game at home (119.2).
  • The Knickerbockers are 16-8 against the spread when they are home favorites.
  • The Lakers are 6-7 as a road underdog.

Lakers vs. Knicks Picks for PrizePicks Today: Sunday, February 1

Here are two top Lakers vs. Knicks picks to target on Sunday. Lakers PG Luka Doncic and Knicks SF OG Anunoby headline key PrizePicks player projections.

Lakers G Luka Doncic vs. Knicks Projection: 32.5 Points

  • Doncic is the top scorer in the league, pouring in 33.7 points per game.
  • The former first-round pick has scored 30+ points in 71.8% of games played this year, the highest share in the NBA.
  • The Slovenian MVP candidate averages a career 30.5 PPG against the Knicks, his third-highest among Eastern Conference opponents.
  • The former Mavericks guard leads the league with a 36.5% usage rate.
  • The Knicks have a 118.1 defensive rating against PGs, the highest among any position.

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Knicks SF OG Anunoby vs. Lakers Projection: 16.5 Points

  • Anunoby has more than 16 points in nine of his last 15 games.
  • The Lakers are allowing 26.6 PPG to SFs, the highest in the NBA.
  • According to databallr, the former first-rounder out of Indiana’s 5.1 shots at the rim puts him in the 84th percentile, and he's shooting 66.3% from within five feet.
  • Via Dunks and Threes, Los Angeles ranks 28th in opponent shooting percentage at the rim (68.5%).

Make Lakers vs. Knicks Picks on PrizePicks

Lakers vs. Knicks picks aren’t the only avenue hoops fans have to joining Sunday's NBA action.

You can make your picks on PrizePicks and PrizePicks Team Picks and earn real money. Just pick players, predict More or Less on their projected stats, and cash in if you’re correct. With Team Picks, make predictions on winners, spreads, and over/unders, now available in 30 states. 

Stick around with the Playbook for continued NBA predictions, picks, and news.

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Team Picks and Culture Picks are event contracts offered by Performance Predictions II, LLC d/b/a PrizePicks Predict, a CFTC-registered FCM and NFA Member. All event contract customers must be U.S. residents and 18+. Some event contracts may not be available in every state. Event contract trading carries significant risk and is not appropriate for everyone. No guarantee against loss is offered. Past results are not necessarily indicative of future results. Void where prohibited by law. Restrictions apply. For full terms of service see prizepicks.com/predict-regulatory. Team and Culture Pick Early Payouts subject to market liquidity. The content provided is for informational and educational purposes only and does not constitute investment advice, or a recommendation to trade any commodity interest.

about the author

John is a graduate from Quinnipiac University with a Master’s Degree in Sports Journalism. With almost 15 years working in radio, TV and blogs, it includes stops at ESPN, NBC Sports, and Audacy. Along with being an avid sports fan, he is into fitness and cooking.

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