The Cleveland Cavaliers (45-27) look to continue their torrid play when they face off against the Miami Heat (38-34) in an Eastern Conference showdown on Wednesday, March 25.
The Cavaliers and Heat have met twice this season, with the teams splitting the two meetings so far. Tip-off for Wednesday’s matchup is scheduled for 7:30 p.m. ET, with the Cavaliers listed as 1.5-point favorites.
Below, we’ll break down our Heat vs. Cavaliers prediction and picks for Wednesday night's game. Make your NBA picks on PrizePicks and earn real money if you’re right, including on game winners, spreads, and totals!
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Heat vs. Cavaliers Prediction, Spread, Over/Under
The Cavaliers continue to try to rise in the Eastern Conference standings late in the regular season. Cleveland currently sits in fourth place in the East but is only 2.5 games behind the Boston Celtics and New York Knicks for second place.
Part of the reason for Cleveland’s rise has been its recent four-game winning streak. SG Donovan Mitchell has been dominant, averaging 27.6 points and 5.6 assists over his last five games.
Miami floundered over the last two weeks, currently on a five-game losing skid. The Heat haven’t had an easy schedule, however, facing the Houston Rockets, Los Angeles Lakers, and San Antonio Spurs over their last three games alone.
SG Tyler Herro has begun to regain his form after being sidelined due to multiple injuries. In March, Herro's enjoyed averages of 22.1 points, 6.1 rebounds, and 4.4 assists while shooting 40.6% from beyond the arc.
Heat vs. Cavaliers Spread, Over/Under
The Cavaliers are 1.5-point home favorites, returning a 1.66x payout on PrizePicks Team Picks if they win outright.
The Heat are slight road underdogs and return a 2.17x payout if they win outright, per PrizePicks Team Picks, where you can earn money with your picks in 35 states.
- Spread: Cleveland Cavaliers -1.5
- Over/Under: 242.5
- Game Winner Payout: Heat 2.17x | Cavaliers 1.66x
Team Picks data is live as of writing and is subject to change.
Heat vs. Cavaliers Injury Report
Let’s dive into the full Heat vs. Cavaliers injury report for Wednesday, via NBA.com.
Miami Heat Injury Report
- PF Nikola Jovic (back): Available
- F Andrew Wiggins (toe): Available
Cleveland Cavaliers Injury Report
- C Jarrett Allen (knee): OUT
- PF-C Larry Nance Jr. (illness): Questionable
- PG Craig Porter Jr. (groin): OUT
- SF Max Strus (foot): OUT
- SG Jaylon Tyson (toe): OUT
Heat vs. Cavaliers Prediction on Spread – 3/25/26
Here are the key stats to know before locking in your Heat vs. Cavaliers prediction against the spread for Wednesday, March 25, on PrizePicks.
- The Cavaliers have a 12-21 against-the-spread record as a home favorite, producing the NBA’s second-lowest cover rate (36.4%).
- The Heat are 15-11 ATS as a road underdog and are 6-4 ATS overall across their last 10 games.
- Miami holds its opponents to a 35.1% shooting percentage from deep, sixth-lowest in the NBA.
- The Heat average 120.2 PPG, trailing only the Denver Nuggets (120.9).
- The Cavaliers are 4-7 ATS on zero days' rest. Cleveland defeated the Orlando Magic on Tuesday.
Heat vs. Cavaliers Picks for PrizePicks Today: 3/25/26
Here are two of the top Heat vs. Cavaliers picks to consider for Wednesday, March 25. Today's PrizePicks NBA player picks feature Cavaliers PF Evan Mobley and Heat F Andrew Wiggins.
Cavaliers PF Evan Mobley vs. Heat Projection: 27.5 Pts + Rebs
- Mobley has averaged a combined 31.0 points and rebounds over his last 10 games.
- The Cavaliers' standout PF has recorded at least 28 points and rebounds in seven of his last 10 contests.
- According to NBA Advanced Stats, Mobley's secured 45.0% of his contested rebound opportunities.
- Mobley has pulled down at least 11 rebounds in three of his last five games.
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Heat F Andrew Wiggins vs. Rockets Projection: 19.5 Pts + Rebs + Asts
- Wiggins has averaged 23.9 points, rebounds, and assists across his last 10 contests.
- The Heat forward has reached at least 20 PRA in eight of his last 10.
- According to databallr, Wiggins registers 20.5 true shot attempts per 100 possessions, ranking in the 77th percentile.
- Wiggins has averaged 15.4 PPG across his last 10 contests.
Make Heat vs. Cavaliers Picks on PrizePicks
Wednesday’s contest features two teams that are headed in two very different directions. The Cavaliers are currently riding a four-game winning streak, while the Heat have lost five straight.
You can make Heat vs. Cavaliers picks on PrizePicks and PrizePicks Team Picks to earn real money. Just pick players, predict More or Less on their projected stats, and cash in if you’re correct. With Team Picks, make predictions on winners, spreads, and over/unders, now available in 35 states.
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