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Giants vs. Dodgers Prediction, MLB Picks for Monday, May 11

Los Angeles Dodgers 1B Freddie Freeman hits a ball during a game against the San Diego Padres.
AP Photo/Derrick Tuskan

The San Francisco Giants vs. Los Angeles Dodgers game is set for a first pitch at 10:10 p.m. ET on Monday, May 11, with the Dodgers entering as favorites and returning a 1.51x payout with a win, via PrizePicks.

The Dodgers (24-16) dropped the final two games of their home series with the Atlanta Braves to fall into a first-place tie with the San Diego Padres atop the National League West.

The Giants (16-24), meanwhile, captured their fourth home series victory in the past five tries following Sunday’s 12-inning triumph over the Pittsburgh Pirates.

Below, we'll break down our Giants vs. Dodgers prediction and picks for Monday's MLB game, including the winner, over/under, and key player picks for PrizePicks.

Make your Giants vs. Dodgers picks on PrizePicks now.

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Giants vs. Dodgers Prediction, Winner Payout, Over/Under – Monday, May 11

San Francisco has found moderate success at home but has struggled mightily on the road. The Giants were swept in their last two series at the Philadelphia Phillies and Tampa Bay Rays, falling to 6-12 away from Oracle Park.

The Dodgers look to bust out of a slump, losing seven of the last 11 games. Los Angeles seeks its fourth series-opening victory in the last five tries, capped off by a 3-1 victory over Atlanta on Friday.

San Francisco SP Logan Webb was slated to start tonight but is sidelined with right knee bursitis. Trevor McDonald makes his second start of the season in his place, trying to capitalize off a strong seven-inning effort against the Padres last Monday.

L.A.’s offense hit the skids against Atlanta, scoring a total of 7 runs in the three games after putting up 12 runs in last Wednesday’s rout of the Houston Astros.

The Dodgers aim for revenge after a series loss at San Francisco last month. The Giants grabbed the first two games before the Dodgers avoided a sweep in a 3-0 shutout on April 23. 

Giants vs. Dodgers Winner Payout, Over/Under – Monday, May 11

The Dodgers enter Monday’s game as a home favorite against the Giants, returning a 1.51x payout if they win outright, via PrizePicks Team Picks.

Here are the full payouts for the Giants vs. Dodgers game on PrizePicks.

  • Spread: Los Angeles Dodgers -1.5 (2x payout)
  • Over/Under: 9.5 (1.96x payout on Over)
  • Game Winner Payout: Giants 2.43x | Dodgers 1.51x
Play the Giants vs. Dodgers winner or over/under on PrizePicks Team Picks to earn real money — available in 35 states!

Team Picks data is live at the time of writing and is subject to change.


Giants vs. Dodgers Prediction on Over/Under – 5/11/26

Here are the key game stats and trends behind our Giants vs. Dodgers prediction on over/under for Monday, May 11.

Lock in your Giants vs. Dodgers prediction on PrizePicks now.
  • The Giants are 4-0 to the under in their last four series openers.
  • All three games between these NL West rivals stayed below the projected total in late April, moving the under to 5-1-1 in the last seven matchups.
  • In five of the last seven road games, San Francisco has been limited to 2 or fewer runs.
  • In two of Dodgers P Roki Sasaki’s three home starts, Los Angeles and its opponents combined for 7 or fewer runs.
  • San Francisco owns a .290 OBP on the road, tied for 25th in MLB. The Giants rank 22nd in road slugging at .363, two points higher than at home.
  • Sasaki is allowing a wOBA of .411, but San Francisco sits 29th in wOBA at .289.

Giants vs. Dodgers Player Picks, Stats for PrizePicks: 5/11/26

Here are top Giants vs. Dodgers picks to target on PrizePicks for Monday, May 11. Today’s MLB picks for PrizePicks include P Trevor McDonald and 1B Freddie Freeman.

Giants P Trevor McDonald vs. Dodgers Projection: 4 Strikeouts

  • McDonald delivered 8 strikeouts against San Diego in his first start of the season on May 4.
  • The Dodgers struck out 23 times against the three Braves starting pitchers (Chris Sale, Spencer Strider, and Bryce Elder).
  • The right-hander pitched well against the Dodgers last September, giving up 6 hits and 1 run in 6 innings of work.
  • Three Dodgers hitters own strikeout rates of 23% or higher: LF Teoscar Hernandez (29.6%), 3B Max Muncy (24.3%), and DH Shohei Ohtani (23.4%). 

Add Trevor McDonald to your PrizePicks Lineup now.

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Dodgers 1B Freddie Freeman vs. Giants Projection: 6.5 Hitter Fantasy Score

  • Freeman finished 3-for-11 against the Giants in last month’s series. All three hits were singles, and he didn’t drive in a run.
  • The veteran slugger struggled against his former team this past weekend, picking up 1 hit in 10 at-bats. His only hit was a solo home run in Friday’s 3-1 victory.
  • In four of the last five home games, Freeman finished below this projection.
  • Freeman is batting just .190 against sinkers, which is McDonald’s top pitch. The right-hander held San Diego to an .067 average on 51 sinkers in his first start.

Add Freddie Freeman to your PrizePicks Lineup now.


Make Giants vs. Dodgers Picks on PrizePicks

San Francisco stunned Los Angeles last month, and now the two rivals link up for a four-game series at Dodger Stadium. Can L.A. get its offense rolling tonight after a rough weekend against Atlanta?

Don’t wait until lock — make your Giants vs. Dodgers picks on PrizePicks now and earn real money if you’re right.

Pick players, predict More or Less on their stats, and cash in if you’re right. With Team Picks, you can make predictions on game winners, spreads, and over/unders, now available in 35 states.

Stay locked in on Playbook for daily MLB predictions, picks, and news every day all the way through the 2026 World Series.

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Team Picks and Culture Picks are event contracts offered by Performance Predictions II, LLC d/b/a PrizePicks Predict, a CFTC-registered FCM and NFA Member. All event contract customers must be U.S. residents and 18+. Some event contracts may not be available in every state. Event contract trading carries significant risk and is not appropriate for everyone. No guarantee against loss is offered. Past results are not necessarily indicative of future results. Void where prohibited by law. Restrictions apply. For full terms of service see prizepicks.com/predict-regulatory. Team and Culture Pick Early Payouts subject to market liquidity. The content provided is for informational and educational purposes only and does not constitute investment advice, or a recommendation to trade any commodity interest.

about the author

Kevin has spent the last 15 years in the sports gambling space. He covered all major sports at VegasInsider both as a writer and handicapper from 2009 until 2024. He has also covered college basketball and MLB for the Action Network.

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