Fantasy Football Buy Low, Sell High for Week 4: Drake Maye, Omarion Hampton, More

NFL Week 3 delivered some of the season's most exciting games so far. History backs that up, as Week 3 tied a record with 12 games settled by one score.

Through these exciting games, we have discovered that some players might be worth trading for in fantasy football, while others may be time to trade away.

Now it's time to assess where fantasy rosters stand and start making moves for the real stretch of the season.

Let’s analyze the players to buy low or sell high ahead of Week 4 of the 2026 NFL season, along with each player's PrizePicks projections for the upcoming week.

Make your Week 4 NFL predictions on PrizePicks — including players and game winners!

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2026 Fantasy Football Buy Low Players for Week 4

Here are some key buy-low players you should consider trading for ahead of Week 4, along with their PrizePicks projection PrizePicks this week.

All stats via PFF, NFL Next Gen Stats, and rankings via FantasyPros.

Patriots QB Drake Maye – Buy Low

Week 4 Matchup: @ Bills

We cannot give up on 2025 NFL MVP runner-up Drake Maye based on what we saw from him last season. This quarterback, just nine months ago, finished second in MVP voting, ranked as 2025 fantasy football QB2, and was first in QB expected points added (EPA).

Unfortunately, the 2026 season has started poorly. The third-year QB already has 7 turnovers, compared to the 11 he had all of last year. The worst part is that Maye’s lack of judgment has cost the Patriots points, as some of those turnovers have happened in the red zone.

A reason for Maye’s early struggles could be the absence of his top target. Maye didn't have WR A.J. Brown for an entire game, as Brown suffered an ankle sprain in the first half of Week 1 against the Seahawks. Brown’s return will significantly upgrade the New England offense; he's eligible to return from IR in Week 6. 

Maye also had a difficult start to the season, facing the Seahawks, Jaguars, and Steelers in rainy conditions — a stark contrast to his cakewalk schedule in2025. However, his schedule is about to become much more favorable.

Five of his next nine games are against the Bills (twice), Dolphins, Lions, and Chargers, all of whom rank among the bottom 11 in fantasy points allowed to quarterbacks.

Next week vs. Buffalo could be the first big performance of the season to start turning it around. The fantasy owner who currently has Maye could be 0-3 and in desperation mode. They might be ready to make a move.

Drake Maye vs. Bills Projections for Week 4

Here are Maye’s projections vs. Bills via PrizePicks — pick More or Less on player stats to cash in every week.

• 233.5 Pass Yards
• 26.5 Rush Yards
• 0.5 Anytime TDs (Demon)
• 1.5 Pass TDs

Pick Drake Maye + Patriots to cover the spread vs. Bills on PrizePicks now!

Cowboys WR George Pickens – Buy Low

Week 4 Matchup: @ Texans

Last season, Pickens and WR CeeDee Lamb were both productive and fantasy-relevant in the Cowboys' offense. Pickens had four top-20 finishes with Lamb on the field, and an additional two when Lamb was injured.

The results aren’t there, with Pickens ranked as the WR33 in fantasy football, but Cowboys QB Dak Prescott hasn't forgotten about him. Entering Week 3, Pickens had 14 targets. In the game against the Ravens, Pickens saw a team-high 11 targets and tied Lamb with 7 receptions. With Pickens trending in the right direction, he should be someone to add to your fantasy team.

Pickens also has a favorable schedule coming up. According to Full Time Fantasy, the Cowboys have the tenth-easiest fantasy schedule for wide receivers for the remainder of the year.

Next week, Dallas faces Houston, and although the Texans had one of the league's best defenses last season, they are struggling to start the 2026 season. The Texans come into this matchup allowing the third-most points per game to wide receivers (33.8).

George Pickens vs. Texans Projections for Week 4

Here are Pickens’ projections vs. Texans via PrizePicks — pick More or Less on player stats to cash in every week.

• 65.5 Rec Yards
• 1.5 Anytime TDs (Demon)

Pick George Pickens + Cowboys to win vs. Texans on PrizePicks now!

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Panthers WR Tetairoa McMillan – Buy Low

Week 4 Matchup: vs. Lions

Tet McMillan is the Panthers' No. 1 wide receiver on the depth chart, but he isn't producing the results expected of a WR1. 

He is still getting plenty of opportunities; according to PlayerProfiler, he ranks fourth in the league among wide receivers in red-zone targets (4), ninth in route participation (90.2%), and 15th in first-read targets (12). 

Early in the season, Panthers WR Jalen Coker has been involved in the offense, with Coker and McMillan each recording 18 targets. During the Week 3 matchup against the Browns, Coker suffered a quad injury. If Coker misses time, McMillan could see a big increase in targets.

In Week 4, the Panthers face the Lions, who rank 29th in fantasy points allowed per game to wide receivers. 

Tetairoa McMillan vs. Lions Projections for Week 4

Here are McMillan’s projections vs. Lions via PrizePicks — pick More or Less on player stats to cash in every week.

• 68.5 Rec Yards
• 1.5 Anytime TDs (Demon)

Pick Tetairoa McMillan + Panthers to win vs. Lions on PrizePicks now!

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2026 Fantasy Football Sell High Players – Week 4

Here are some key players to sell high on for fantasy football after overachieving, plus their projections on PrizePicks this week.

Steelers RB Jaylen Warren – Sell High

Week 4 Matchup: @ Browns

Jaylen Warren has been a mainstay in the Steelers offense, entering his fifth season with the team.

During that time, Warren usually shared the backfield with former Steelers RB Najee Harris. With Harris signing with the Chargers in 2025, Warren saw increased volume, posting career highs in carries (210), rushing yards (958), and rushing touchdowns (8).

How did the Steelers show their appreciation? They signed RB Rico Dowdle in the offseason. Steelers head coach Mike McCarthy knows Dowdle because he signed him as an undrafted free agent while he was the Cowboys' head coach in 2020.

In Week 1, Dowdle got most of the playing time, out-snapping Warren 39-25. Warren ended up with a heavy workload in Week 2 after Dowdle left the game in the first half.

Dowdle’s injury does not appear to be long-term, so when he’s healthy, he could be right back in the lineup, and Warren will see his snaps diminish, with his bellcow status in the rearview mirror.

Jaylen Warren vs. Browns Projections for Week 4

Here are Warren’s projections vs. Browns via PrizePicks — pick More or Less on player stats to cash in every week.

• 65.5 Rush Yards
• 22.5 Rec Yards
• 1.5 Anytime TDs (Demon)
• 3.5 Receptions
• 11 Fantasy Score

Pick Jaylen Warren + Steelers to win vs. Browns on PrizePicks now!

Chargers RB Omarion Hampton – Sell High

Week 4 Matchup: @ Seahawks

Of the two running backs taken in the first round of last year’s draft, one continues to ascend, while the other hasn’t lived up to expectations. 

Raiders RB Ashton Jeanty has been a standout fantasy running back since entering the league and ranks as the RB7 this season. 

Unfortunately for Hampton, he has not had the same success. He enters Week 4 ranked RB22, and his situation doesn’t look like it's improving. The Chargers offense is a mess, ranking 29th in EPA per play (-0.21). 

It doesn’t help that Chargers OC Mike McDaniel has split carries among the running backs. In Week 3, the running back-by-committee approach was evident, with RB Alec Ingold leading the team with 31 snaps, Hampton getting 29 snaps, RB Keaton Mitchell with 26 snaps, and Kimani Vidal with 17.

With Dolphins RB De’Von Achane done for the year with a torn ACL and Jets RB Breece Hall dealing with a quad injury, fantasy managers may be inclined to pay for Hampton’s potential, needing a RB who is guaranteed to be on the field.

Omarion Hampton vs. Seahawks Projections for Week 4

Here are Hampton’s projections vs. Seahawks via PrizePicks — pick More or Less on player stats to cash in every week.

• 50.5 Rush Yards
• 13.5 Rush Attempts
• 5.5 Receiving Yards
• 0.5 Anytime TDs

Pick Omarion Hampton + Chargers to cover the spread vs. Seahawks on PrizePicks now!

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Jets TE Kenyon Sadiq – Sell High

Week 4 Matchup: @ Bears

If you want to see the textbook definition of a sell-high candidate, then look at Jets rookie TE Kenyon Sadiq. The Jets tight end had just 5 catches for 38 yards in two games, then exploded for 105 yards on 7 catches and a TD in Week 3. 

A big reason for this breakout performance is the opponent. The Lions’ defense has been terrible to start the year, allowing the second-most yards per game (416.7) and has allowed at least 11 fantasy points to tight ends in each of the three games.

In addition, Jets TE Mason Taylor missed Week 3 with a thumb injury, but should return soon; Taylor led all Jets tight ends in snaps in Week 1 and 2 before the injury.

This week may be the best chance to sell Sadiq, as his schedule gets tougher. According to Full Time Fantasy, the Jets have the third-worst remaining schedule for tight ends. In fact, the Jets’ strength of schedule for each offensive position ranks outside the top 24. 

Tough times could be ahead for the entire Jets offense.

Pick Kenyon Sadiq + Jets to win vs. Buccaneers on PrizePicks now!

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Make NFL Week 4 Picks on PrizePicks

We’re three weeks into the 2026 fantasy football season, and it’s time to make moves if your roster is struggling. There is still plenty of time to save the season, and a couple of trades can make it into a championship contender.

If you want to manage a different lineup each week throughout the NFL season, you can do it on PrizePicks. Don’t wait until kickoff — make your NFL picks on PrizePicks now and earn real money if you’re right.

Pick players, predict More or Less on their stats, and cash in if you’re right. With Team Picks, you can make predictions on NFL game winners, spreads, and over/unders, now available in 36 states.

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