The Arizona Diamondbacks (0-2) will be looking to avoid a three-game sweep when they take on the Los Angeles Dodgers (2-0) on Saturday, March 28. The NL West rivals will face off at 9:10 p.m. ET tonight.
The Dodgers won the opening two games of the series, but they were only 7-6 vs. the Diamondbacks in the 2025 campaign. Dodgers SP Tyler Glasnow (3.72 xFIP in 2025) vs. Diamondbacks SP Eduardo Rodriguez (4.44 xFIP in 2025) is an intriguing battle of two veteran arms on the mound today.
Below, we’ll break down our Diamondbacks vs. Dodgers prediction and picks for today’s game. Make your MLB picks on PrizePicks and earn real money if you’re right, including on game winners, spreads, and totals!
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Diamondbacks vs. Dodgers Prediction, Spread, Over/Under
The Dodgers’ pursuit of a third consecutive World Series title has gotten off to a strong start. Los Angeles has taken the opening two games of the series and outscored Arizona 13-6 in the process.
After falling behind 2-0 in Thursday’s season opener, the Dodgers exploded for 8 unanswered runs, highlighted by a 3-run home run from OF Andy Pages in the fifth inning. Off-season acquisition Kyle Tucker also recorded an RBI double, and C Will Smith slugged a 2-run home run to put the ball out of reach.
In Friday’s contest, it was a back-and-forth affair that featured multiple lead changes. When trailing in the third inning, Dodgers SS Mookie Betts belted a 3-run home run to give his team a 4-2 advantage.
Diamondbacks OF Alek Thomas recorded a game-tying 2-run double in the fourth inning, where the team stayed deadlocked for multiple frames. Ultimately, Tucker was able to score 2B Alex Freeland on an RBI single, which turned out to be the game-winning run.
The Dodgers will be looking to get off to an early 3-0 start on Saturday.
Diamondbacks vs. Dodgers Spread, Over/Under
The Diamondbacks are road underdogs today, returning a 2.94x payout on PrizePicks Team Picks if they win outright.
The Dodgers are home favorites and return a 1.4x payout if they win outright, per PrizePicks Team Picks, where you can earn money with your picks in 35 states.
- Spread: Los Angeles Dodgers -1.5 (1.85x payout)
- Over/Under: 8.5 Runs (1.75x payout on over)
- Game Winner Payout: Diamondbacks 2.94x | Dodgers 1.4x
Team Picks data is live as of writing and is subject to change.
Diamondbacks vs. Dodgers Prediction on Spread – 3/28/26
Here are the key stats to know before locking in your Diamondbacks vs. Dodgers prediction on the 1.5-run spread for Saturday, March 28, on PrizePicks.
- The Dodgers had a 38-50 record against the spread (ATS) as a home favorite in 2025, producing a 43.2% cover rate (ninth-best in MLB).
- Los Angeles is 1-1 ATS in its first two games of 2026.
- The Diamondbacks were 33-18 ATS as a road underdog in 2025.
- Los Angeles scored the second-most runs (13) through two games, behind only Milwaukee (14).
- Dodgers SP Tyler Glasnow has struggled vs. the Diamondbacks in his career, producing a 0-4 record and a 7.71 ERA over six career appearances.
- The Diamondbacks excelled at the plate on the road throughout the 2025 season, producing the fifth-ranked wRC+ (105) in the majors, per FanGraphs.
- Los Angeles is one of 14 MLB teams that have yet to record an error this season.
- The Dodgers won five of the last six meetings outright but only won two of those games by at least 2 runs.
- Diamondbacks SP Eduardo Rodriguez has a 2-4 record and a 6.06 ERA in seven starts vs. the Dodgers in his career.
- According to FanGraphs, the Diamondbacks starter put together a 9.77 K/9, a 3.89 xFIP, and a 38.1% ground ball percentage in 82.0 road innings.
Diamondbacks vs. Dodgers Picks for PrizePicks Today: 3/28/26
Here are two of the top Diamondbacks vs. Dodgers picks to consider for Saturday, March 28. Today's PrizePicks MLB player picks feature Diamondbacks 2B Ketel Marte and Dodgers SS Mookie Betts.
Diamondbacks 2B Ketel Marte vs. Dodgers Projection: 1.5 Hits + Runs + RBIs
- Marte has a .285 batting average (126-for-442) with 13 home runs, 43 RBI, and 56 runs scored in 117 career games vs. the Dodgers.
- The Diamondbacks 2B went 2-for-5 with a solo home run in Friday’s 5-4 loss vs. the Dodgers.
- According to Baseball Savant, Marte registered a 13.5% barrel percentage in 2025, which ranked in the 83rd percentile.
- Marte is 2-for-6 with an RBI in seven plate appearances vs. Dodgers SP Tyler Glasnow.
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Dodgers SS Mookie Betts vs. Diamondbacks Projection: 1.5 Total Bases
- Betts is just 3-for-11 in 14 plate appearances vs. Diamondbacks SP Eduardo Rodriguez with no extra-base hits.
- The Dodgers star tallied 1 hit in two games vs. Rodriguez during the 2025 season.
- Betts has produced a .250/.333/.625 slash line in two games vs. the Diamondbacks in this series.
- The Dodgers' SS had 13 extra-base hits vs. left-handed pitchers in 2025.
Make Diamondbacks vs. Dodgers Picks on PrizePicks
The 2026 MLB season is officially in full swing, with the Dodgers continuing their series vs. the Diamondbacks. Los Angeles will look to remain undefeated against its NL West rivals, while Arizona aims to avoid falling into a 0-3 hole to start off the new campaign.
You can make Diamondbacks vs. Dodgers picks on PrizePicks and PrizePicks Team Picks to earn real money. Just pick MLB players, predict More or Less on their projected stats, and cash in if you’re correct. And with Team Picks, you can make predictions on winners, spreads, and over/unders, now available in 35 states.
Stick around with the Playbook for continued MLB predictions, picks, and news throughout the 2026 season.
