College football Week 10 is one of those days you're just gonna wanna be glued to the TV. Actually, multiple TVs, if possible. This is the best Saturday of the year, and we've got your full college football schedule, TV channels, spreads and previews for every key game below.
Seven ranked-vs.-ranked matchups run from noon to 7:30 p.m. ET, all in the first week after the College Football Playoff committee released its initial rankings. Now we find out who's real and who's a fraud.
The day opens with the first top-10 Holy War ever, #9 BYU vs. #3 Utah at noon on ABC, and closes with a primetime double feature: #1 Miami vs. #11 Notre Dame on NBC and #2 Georgia vs. #10 Ole Miss on ABC, both at 7:30 p.m. ET.
In between, #5 Alabama visits #14 LSU and #23 Oregon visits #12 Ohio State at 3:30 p.m. ET, and #6 Kentucky heads to #13 Tennessee at 6:15 p.m. ET.
On PrizePicks, you can pick every one of these games on winners and spreads with Team Picks, or pair them with Player Picks in the same lineup.
Make your Week 10 college football picks on PrizePicks — including winners and spreads!
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College Football Games Today: NCAAF Week 10 Schedule, TV Channels, & Spreads
Here's the full college football Week 10 schedule for Saturday, November 7, with kickoff times (ET), TV channels, and spreads and payouts to win on PrizePicks Team Picks. Rankings are from the Nov. 3 College Football Playoff rankings.
The spreads and payouts to win are live on PrizePicks Team Picks as of posting, but are subject to change. In the To Win column, the first payout is for the first team listed.
College Football spreads via PrizePicks — make CFB picks on spreads and winners now!
How to Watch College Football Games Today – Saturday, November 7
#9 BYU vs. #3 Utah – 12:00 p.m. ET
How to watch: ABC, 12 p.m. ET, Rice-Eccles Stadium, Salt Lake City
Spread: UTAH -4.5
The Holy War has never been bigger. For the first time in the history of the rivalry, BYU and Utah meet with both ranked in the top 10, and the winner takes a big step toward the Big 12 Championship Game and a College Football Playoff spot.
Utah is 8-0 and #3 in the first CFP rankings, chasing a first-round bye in Morgan Scalley's first Holy War as head coach. BYU (7-1) has won three straight in the series and already owns a win over Notre Dame. Expect a ground game battle: these two teams combine for more than 400 rushing yards per game.
#7 Texas vs. #18 Missouri – 12:00 p.m. ET
How to watch: ESPN, 12 p.m. ET, Memorial Stadium, Columbia, Mo.
Spread: TEX -2.5
Both teams are 6-2 and 3-2 in SEC play, and the loser takes a third loss into the final month. Texas is back on track after wins over Ole Miss and Mississippi State, and the Longhorns haven't lost a true road game this season.
Missouri is a tough out at home, going 25-4 in Columbia since 2023 behind QB Austin Simmons. Arch Manning has 15 TD passes on the year, but Texas could be thin at receiver, running back, and missing their left tackle. It's the tightest spread among today's ranked matchups, and it's moved toward Missouri this week.
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#5 Alabama vs. #14 LSU – 3:30 p.m. ET
How to watch: ABC, 3:30 p.m. ET, Tiger Stadium, Baton Rouge, La.
Spread: LSU -5.5
Both teams are 6-2 and coming off a bye, and one leaves Death Valley with a third loss and playoff hopes on life support. Alabama surprised at #5 in the first CFP rankings, while LSU's two losses came to Ole Miss and Kentucky in overtime.
LSU head coach Lane Kiffin has made his feelings known about the afternoon kickoff, the first non-night meeting in Baton Rouge since 2010. LSU QB Sam Leavitt is second in the SEC with 2,173 passing yards and 17 TDs, with Alabama's Keelon Russell right behind at 2,057 yards.
#23 Oregon vs. #12 Ohio St. – 3:30 p.m. ET
How to watch: CBS, 3:30 p.m. ET, Ohio Stadium, Columbus, Ohio
Spread: OSU -7.5
Two preseason contenders are fighting to save their seasons. Ohio State (6-2) fell 30-18 to USC last week in freshman QB Luke Fahey's first start with Julian Sayin sidelined, and a third loss would put the Buckeyes' playoff hopes in serious danger.
Oregon (5-3) is coming off a 34-26 win over Northwestern behind QB Dylan Raiola, a former Ohio State commit. Fahey threw for 260 yards against USC, and he has Heisman contender WR Jeremiah Smith on the outside as he makes his second career start.
#6 Kentucky vs. #13 Tennessee – 6:15 p.m. ET
How to watch: ESPN, 6:15 p.m. ET, Neyland Stadium, Knoxville, Tenn.
Spread: TENN -5.5
Kentucky (7-1, 5-1 SEC) is tied with Georgia atop the SEC with six straight wins under Will Stein. But Knoxville has been a house of horrors: the Wildcats have lost 19 of their last 20 games there, and Tennessee has won five straight in the series.
Tennessee (6-2) sits just outside the playoff field after a loss to South Carolina and leans on RB DeSean Bishop, who has 957 rushing yards and 11 TDs. Kentucky QB Kenny Minchey has 14 TD passes and one interception, and the Wildcats' +13 turnover margin ranks fourth nationally.
#1 Miami vs. #11 Notre Dame – 7:30 p.m. ET
How to watch: NBC and Peacock, 7:30 p.m. ET, Notre Dame Stadium, South Bend, Ind.
Spread: ND -7.5
The game of the day. Miami is 8-0 and #1 in the first CFP rankings, while Notre Dame (7-1) sits at #11 and needs a signature win to stay in the Playoff field. Miami won last season's meeting 27-24, a loss that helped keep the Irish out of the playoff.
The Heisman stakes are huge: Miami QB Darian Mensah has 2,425 yards, 25 TDs, and 1 INT, while CJ Carr has 18 TD passes and one pick. Miami will be without star WR Malachi Toney, which helps explain why the #1 team is a 7.5-point underdog on PrizePicks.
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#2 Georgia vs. #10 Ole Miss – 7:30 p.m. ET
How to watch: ABC, 7:30 p.m. ET, Vaught-Hemingway Stadium, Oxford, Miss.
Spread: UGA -3.5
It's a rematch of last season's CFP quarterfinal in the Sugar Bowl, which Ole Miss won 39-34. Georgia (7-1, 5-1 SEC) brings the SEC's best scoring defense, allowing 14.9 points per game, after forcing four turnovers against Florida last week, but only facing weaker opposing offenses outside of Alabama.
Ole Miss (6-2) has won 16 straight at home, the longest active streak among Power Four programs, and Trinidad Chambliss leads the SEC with 2,189 passing yards and 18 TDs. Georgia QB Gunner Stockton leads the SEC with a 71.8% completion rate and will need to keep pace.
Make your college football picks on winners and spreads on PrizePicks now!
Week 10 NCAAF Spreads, Winners, Payouts Today on PrizePicks
The tightest spreads among today's ranked matchups are #7 Texas -2.5 vs. #18 Missouri and #2 Georgia -3.5 vs. #10 Ole Miss. Pick Missouri to win at 2.12x, or Ole Miss at home at 2.38x on PrizePicks.
The biggest surprise on the board: #1 Miami is a 7.5-point underdog at #11 Notre Dame, paying 3.03x to win. #23 Oregon pays 3.22x to win at #12 Ohio State, #5 Alabama pays 2.77x at #14 LSU, and #6 Kentucky pays 2.63x at #13 Tennessee.
For the biggest payouts on the board among ranked games, Colorado St. pays 6.25x to win vs. #25 Boise St., West Virginia pays 5.55x at #15 Texas Tech, and Michigan St. pays 5.26x vs. Michigan.
The rest of Week 10 is on the PrizePicks board, and you can add Player Picks to any lineup with your Team Picks for even higher payouts.
The Week 10 CFB schedule is loaded. Lock in your picks on PrizePicks!
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Make Saturday College Football Picks on PrizePicks
With plenty of stellar games at the top, including seven ranked-vs.-ranked matchups on the board, this college football Saturday is loaded. For more on Miami vs. Notre Dame, Georgia vs. Ole Miss, and the rest of today's slate, check out the PrizePicks Playbook College Football home for expert picks and research all day.
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