With one full week of games behind us, College football Week 2 is here. The heat is getting turned up this week, with several must-watch games across the schedule.
All eyes will be on #11 Oklahoma vs. Michigan at 12 p.m. ET and #1 Ohio State vs. #4 Texas at 7:30 p.m. ET, but every window today has plenty of exciting TV games.
Below is the full Week 2 college football schedule for Saturday’s games, the TV channel for every NCAAF game, and current spreads via PrizePicks Team Picks — now available in 35 states!
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College Football Games Today: Week 2 Schedule, TV Channels, & Spreads
All game times are in Eastern Time. Spreads and winner payouts are live on PrizePicks Team Picks as of posting, but are subject to change.
The schedule below encompasses all top 25 teams and TV games — any games on a cable channel — and excludes games on streaming only, such as ESPN+.
Payouts below, like 3x, represent real-money multipliers on correct picks on PrizePicks Team Picks at the time of writing. For example, a $100 entry on Ohio State to win at a 1.96x multiplier would pay out $196 if you're right.
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How to Watch NCAAF Games Today – Saturday, September 12
Today's slate runs nearly 12 hours, from a 12:00 p.m. ET window through a midnight nightcap in Hawai’i, which will go into the early hours of Sunday. The games above are listed across 16 TV networks — excluding streaming in places like ESPN+ or SEC+.
Starting the day in the noon window, all eyes will be on #11 Oklahoma vs. Michigan headlining on FOX, as Michigan returns to the Big House after a controversial win in Week 1. Meanwhile, #6 Oregon will host Oklahoma State on ESPN, after the Ducks survived a scare vs. west-coast rival Boise State.
The afternoon window — starting at 3:30 p.m. ET — is the only one without a must-watch, as #3 Notre Dame is a massive favorite vs. Rice at home. However, we do get two early conference games, as #12 Alabama hosts Kentucky on ABC, and Arizona travels to #15 BYU on FOX.
The main event of the evening will kick off at 7:30 p.m. ET on ABC, as #1 Ohio State matches up with #4 Texas, which sets the stage for both squads for the rest of the season.
If you can multi-task, you’ve got #18 Tennessee vs. Georgia Tech on ESPN, #13 Texas Tech hosting Oregon State on CBS, and Iowa State vs. in-state rival #21 Iowa on NBC — all in the primetime window tonight.
There’s plenty available on the late-night window too — for the real sickos. The headliner will be Arkansas vs. #20 Utah on ESPN at 10:15 p.m. ET, in a cross-conference game that should teach us a lot about both squads. That's followed by #14 USC as a 31.5-point favorite vs. Louisiana at 11 p.m. ET on the Big Ten Network.
Make your college football predictions on winners and spreads on
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Must-Watch NCAAF Games Today – Saturday, September 12
Here are the four games you should slot into the quad-box for Week 2 during each window today.
Best CFB Noon Games Today
- #6 Oregon vs. Oklahoma State – ESPN
- Arizona State vs. #10 Texas A&M – ABC
- #11 Oklahoma vs. Michigan – FOX
- Wake Forest vs. Purdue – FS1 OR USF vs. Army – CBSSN
Best CFB Afternoon Games Today
- #12 Alabama vs. Kentucky – ABC
- Arizona vs. #15 BYU – FOX
- Cal vs. Syracuse – CBSSN
- Mississippi St. vs. Minnesota – CBS
Best NCAAF Night Games Today
- #1 Ohio State vs. #4 Texas – ABC
- Iowa State vs. #21 Iowa – NBC
- #18 Tennessee vs. Georgia Tech – ESPN
- Navy vs. FAU – ESPNU AND/OR Memphis vs. Boise St. – USA Network (6 p.m. ET)
Best NCAAF Late Night Games Today
- North Dakota State vs. Air Force – FS1 (10 p.m. ET)
- Arkansas vs. #20 Utah – ESPN (10:15 p.m. ET)
- Montana State vs. Nevada – CW (10:30 p.m. ET)
- New Mexico St. vs. Hawaii – MW+ (11:59 p.m. ET)
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Week 2 NCAAF Spreads, Winners, Payouts Today on PrizePicks
The headliner of the night is a true pick'em: #1 Ohio State and #4 Texas enter dead even, with no spread favorite on either side. Mississippi State-Minnesota is the only other game with a "Pick" line across the games on TV today.
Beyond that, single-possession games are scattered throughout the day, including UTSA vs. Texas State (1.5), North Dakota State vs. Air Force (1.5), and Wake Forest vs. Purdue (2.5).
But the broader trend today is lopsided, as tends to be the case in non-conference games with ranked teams. Several ranked teams are double-digit-plus favorites, with Rice at #3 Notre Dame (44.5), Charlotte at #9 Ole Miss (43.5), and Louisiana at #14 USC (31.5) among the widest gaps on the board.
The rest of Week 2 is on the PrizePicks board now. In eligible states, you can make picks on college football winners, spreads, and totals. Then add Player Picks to the same lineup for bigger potential payouts.
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Make Saturday College Football Picks & Predictions on PrizePicks
Need some expert picks and predictions before you lock in your college football lineup today? Tap into the Playbook’s Week 2 CFB research from our experts for coverage on the top games today.
Stay locked in on the Playbook college football home for daily picks, predictions, spreads, and game previews throughout the 2026 college football season.
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