Most of the NBA will be in action on Monday night, as 22 teams gear up for Monday’s 11-game slate. The sliding Cleveland Cavaliers (17-16) are looking to knock off one of the league’s best, the San Antonio Spurs (23-9), led by Victor Wembanyama and Stphon Castle.
Cleveland carries a 2-5 record over the previous seven, and the Spurs have an 8-2 record in the last 10 games. In the last head-to-head meeting on Dec. 5, the Cavs defeated San Antonio, 130-117.
Will Cleveland continue that success for tonight’s 8 p.m. ET tipoff in the NBC spotlight?
Let’s make our Cavaliers vs. Spurs prediction, spread, over/under, and break down today's best player picks at PrizePicks for Monday, December 29, 2025.
Cavaliers vs. Spurs Prediction, Spread, Over/Under
In the last 10 matchups vs. the Spurs, Cleveland boasts a 9-1 record and has won six straight.
According to Dunks & Threes, the Spurs rank fifth in adjusted NET rating compared to the Cavaliers at 11th. PrizePicks Team Picks projects Cleveland a 1.03x payout to make the NBA Playoffs, while San Antonio has bigger fish to fry, as the current third favorite to win the NBA Finals with a 7.69x payout.
After missing Saturday’s contest, Spurs PG De’Aaron Fox (adductor) is questionable on the injury report.
Cleveland Cavaliers vs. San Antonio Spurs Over/Under, Spread
PrizePicks Team Picks lists San Antonio as 1.5-point favorites, returning a 1.72x payout with a cover.
After losing back-to-back games on the road, Cleveland features a 2.17x payout for an outright win. Tonight’s 242.5 total implies a high-scoring affair.
- Spread: San Antonio Spurs -1.5 (1.66x payout)
- Over/Under: 242.5 (1.75x payout)
- Gamer Winner Payout: Cavaliers 2.22x | Spurs 1.61x
Team Picks data is live as of publishing and is subject to change.
Cavaliers vs. Spurs Prediction on Spread for 12/29/2025
Tonight’s Cavs vs. Spurs clash features a contrast in styles, with the Cavaliers ranking eighth for the quickest pace while the Spurs are 18th, per NBA Advanced Stats. Furthermore, Cleveland launches 92.7 field goal attempts per game (second), which smashes San Antonio’s per-game average of 89.2 (20th).
Controlling the pace typically comes down to winning the possession battle. The Spurs sport a 76.2% defensive rebounding rate (first) and 27.6% offensive rebounding percentage (eighth). The Cavs, meanwhile, carry marks of 73.1% (18th) and 27.0% (13th).
In the previous head-to-head matchup, Cleveland dominated the interior by controlling the rebounding battle (48-38) and outscoring San Antonio in the paint, 80-44.
However, Spurs F Victor Wembanyama was absent, and he leads the team with 23.9 points per game (PPG), 11.5 rebounds per game (RPG), and 3.1 blocks per contest. FantasyLabs credits Wemby with an elite 105.0 defensive rating, as well.
It’s difficult to put much weight in Cleveland’s 13-point win on December 5, as San Antonio was without Wembanyama and G Stephon Castle. Plus, the Cavaliers' starting G Darius Garland, G Sam Merrill, and C Jarrett Allen were out.
With Wemby in the lineup, the Spurs could get back to dominating the glass. Look for the Spurs to control the pace, with some advantages in shot distribution vs. the Cavs.
Dunks & Threes gives the Cavs a 46.8% 3-point shot distribution (fourth), and San Antonio allows a 40.1% mark from deep (10th).
The Spurs lean on attacking the paint, holding a 34.4% shot distribution around the rim (eighth). Cleveland cedes a 32.6% shot distribution around the rim (18th).
Cavaliers vs. Spurs Picks for PrizePicks NBA Today
Here are the top Cavs vs. Spurs picks for PrizePicks Player Picks today, honing in on Cavaliers G Jaylon Tyson, Spurs G Stephon Castle, and San Antonio F Victor Wembanyama for Monday night’s bout.
Cavaliers G Jaylon Tyson vs. Spurs Projection: 9.5 Points
- Amid a slow start for the Cavaliers, Tyson has pushed for the full-time starting small forward role, totaling 29.2 minutes per game in December.
- He’s posted 16.0 PPG over 12 appearances this month, surpassing his 13.4 PPG on the season.
- The Spurs give up 13.0 made triples per game (14th) and a 36.1% 3-point percentage (17th). The former first-round pick shoots a blistering 44.2% from beyond the arc.
Spurs G Stephon Castle vs. Cavaliers Projection: 18.5 Points
- Since returning from injury on December 8, Castle has posted 20.6 PPG compared to his season-long average of 18.6 PPG.
- The second-year wing’s 26.7% usage rate jumps to 27.5% when Fox is off the court. If the veteran guard is out, more work should come Castle’s way.
- The former UConn Husky makes only 1.2 3-pointers per game, and 55.2% of his shots come from within 10 feet of the basket, via NBA Stats. Remember, the Cavs rank 18th in shot distribution around the rim allowed.
Spurs F Victor Wembanyama vs. Cavaliers Projection: 10.5 Rebounds
- Averaging the fourth-most rebounds per game in the NBA (11.5), Wembanyama could find success on the glass vs. the Cavs.
- After logging only 7.7 RPG in his first three games back from injury, the French phenom has hit 11 boards in three of his last five games.
- Among players with at least 18 games played, Wembanyama’s 28.1% defensive rebounding percentage leads the NBA.
- With the Cavaliers ranking 13th in offensive rebounding rate, Wemby could feast on the defensive glass.
Make Cavaliers vs. Spurs Picks on PrizePicks
Will the Spurs snap a cold streak in head-to-head matchups against the Cavs? Unlike the last meeting on Dec. 5, both teams should feature a mostly healthy rotation, pending Fox’s questionable status.
Make your Cavaliers vs. Spurs picks at PrizePicks, where you can earn real-money rewards for your predictions if you’re right. Just make your pick on the winner, spread, or over/under with Team Picks, or choose players, predict More or Less on their projected stats, and follow the hoops action to see if your picks hit.
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