Cardinals vs. Twins Prediction, MLB Picks for Saturday, June 13

The St. Louis Cardinals (37-30) and the Minnesota Twins (32-39) battle in the second contest of a three-game series on Saturday, June 13, at 2:10 p.m. ET. According to PrizePicks Team Picks, this matchup is currently a toss-up with each team holding a 1.85x payout to win.

Friday’s Game 1 provided fireworks with Minnesota grabbing a 9-8 win. St. Louis racked up 12 hits, but the Twins’ power reigned supreme by launching 4 home runs. Are we tracking for another high-scoring matchup?

Below, we'll break down our Cardinals vs. Twins prediction and picks for Saturday’s MLB matchup, including the winner payouts, over/under, and key player picks for PrizePicks.

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Cardinals vs. Twins Prediction, Winner Payout, Over/Under – Saturday, June 13

While the Cardinals were able to get on base often last night, they totaled only 2 extra-base hits, including 1 double and 1 HR. Meanwhile, the Twins racked up 4 doubles and 4 home runs. Minnesota OF Byron Buxton was like the Human Torch, logging 2 doubles and 1 big fly over 3 at-bats.

On the season, FanGraphs credits the Twins with 4.61 runs per game (ninth), a .316 wOBA (tied for 15th), and 98 wRC+ (tied for 16th). The Cardinals carry 4.57 runs per contest (12th), a .318 wOBA (14th), and 103 wRC+ (tied for 11th).

Over the last 30 days, St. Louis has been the more productive unit with 107 wRC+ (tied for 10th) compared to Minnesota’s 98 wRC+ (19th). The Cardinals sport a 6-2 record in the last eight games, while the Twins are 2-4 over the past six contests.

Today’s starting pitcher matchup brings a duel between left-handed hurlers. St. Louis SP Matthew Liberatore (3-3, 4.12 xFIP in 66.1 IP) takes the mound, and he carries a 5.22 xERA over 13 starts. Minnesota SP Connor Prielipp (2-4, 3.98 xFIP in 43.2 IP) is ahead of Liberatore in advanced metrics, including his 3.72 xERA in nine starts.

Cardinals vs. Twins Winner Payout, Over/Under – Saturday, June 13

Today’s contest is tracking for a pick 'em with both teams returning a 1.85x payout if they win outright, via PrizePicks Team Picks.

Here are the full payouts for the Cardinals vs. Twins game on PrizePicks.

• Over/Under: 8.5 (1.72x payout on Over)
• Game Winner Payout: Cardinals 1.85x | Twins 1.85x

Make your Cardinals vs. Twins prediction on the winner or over/under on PrizePicks Team Picks to earn real money — available in 35 states!

Team Picks data is live at the time of writing and is subject to change.

Cardinals vs. Twins Prediction on Winner – 6/13/26

Here are the key game stats and trends behind our Cardinals vs. Twins prediction on the winner for Saturday, June 13.

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• The Twins have a .229 batting average (tied for 21st), a .348 SLG (27th), and a .308 wOBA (tied for 18th) against left-handed pitchers. In comparison, the Cardinals boast a .248 batting average (ninth), .387 SLG (13th), and .318 wOBA (12th) in the split.
• Cardinals SP Matthew Liberatore carries a 3.68 ERA while yielding only 2 home runs over his last three starts. That’s a notable improvement from his 1.49 HR/9 for the season.
• Twins rookie SP Connor Prielipp is trending in the opposite direction with an 8.20 ERA over his last four appearances.
• Minnesota’s fifth-best prospect has a 9.4% walk rate (40th percentile), per Baseball Savant. He’s walked 2.3 batters per start over his last four outings, and St. Louis just tallied 3 walks on Friday night.
• Prielipp cedes a 44.1% fly ball rate that’s above the 39.1% league average, paired with a 9.2% barrel rate allowed (29th percentile).
• The Cards tout the power to make the rookie pay, proven by a .414 xSLG (10th).

Cardinals vs. Twins Picks, Player Stats for PrizePicks Today

Here are the top Cardinals vs. Twins picks to target on PrizePicks for Saturday, June 13. Today’s MLB picks for PrizePicks include Jordan Walker and Byron Buxton.

Cardinals OF Jordan Walker vs. Twins: 6.5 Hitter Fantasy Score

• Cardinals OF Jordan Walker tops the team with a 46.0% hard-hit rate and 22.7% home run-to-fly ball rate (HR/FB). 
• Plus, Baseball Savant gives the slugger a 94.3 average exit velocity (98th percentile), 13.2% barrel rate (81st percentile), and 79.1 bat speed (100th percentile).
• His production doesn’t drop off against lefties either, as he carries a .290 batting average and .629 SLG vs. southpaws compared to .303 and .535 against righties.
• As mentioned, Connor Prielipp can be vulnerable against sluggers by allowing a 9.2% barrel rate (29th percentile) and an 89.7 average exit velocity (31st percentile). 
• Walker is red-hot to begin June with a .348/.348/.587 slash line. This includes an 11.2 hitter fantasy score per game over his last five contests.

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Twins Byron Buxton vs. Cardinals: 1.5 Total Bases

• As a unit, the Twins’ numbers plummet against left-handed pitching, but that’s not the case for star outfielder Byron Buxton.
• Buxton touts a strong .273/.333/.409 slash line against southpaws, compared to .263/.326/.651 against righties.
• His slugging may dip against left-handed hurlers, but Matthew Liberatore yields a 9.4% barrel rate (27th percentile) and a 44.1% hard-hit rate (16th percentile).
• Buxton certainly carries the numbers to expose the weakness, including a .504 xSLG (89th percentile) and a 19.0% barrel rate (98th percentile).
• Liberatore’s most-used pitch is a four-seam fastball (33.1%), and Minnesota’s center fielder bats .297 against the pitch.
• After tallying 8 total bases on Friday night, Buxton has recorded 3.4 bases per game over his last five appearances.

Add Byron Buxton to your PrizePicks Lineup now.

Make Cardinals vs. Twins Picks on PrizePicks

Following Friday’s 17 combined run total, the Cardinals vs. Twins features another vulnerable starting pitcher matchup. Stars like Jordan Walker and Byron Buxton could keep swinging hot bats on Saturday afternoon.

Don’t wait until the first pitch — make your Cardinals vs. Twins picks on PrizePicks now and earn real money if you’re right.

Pick players, predict More or Less on their stats, and cash in if you’re right. With Team Picks, you can make predictions on game winners, spreads, and over/unders, now available in 35 states.

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