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Week 6 features a handful of marquee matchups across the NFL, which should lead to notable performances from a plethora of players. Luckily for fans, PrizePicks offers an abundance of projections each week, including pass yards, rush yards, targets, and more.
With the stars in action in Week 6, which players stand out across Sunday’s contests?
Below, we'll bring you our top NFL DFS picks for PrizePicks, where you can predict More or Less on player stats to earn real money if you're right!
Make your Week 6 NFL predictions and picks on PrizePicks!
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Week 6 NFL DFS Picks for PrizePicks – Sunday, October 18
Here are the top Week 6 NFL DFS picks to target on PrizePicks for Sunday, October 18.
Today’s NFL picks include Brock Bowers, Puka Nacua, Germie Bernard, Isaiah Likely, and Tony Pollard.
Stats in this article are courtesy of PFF or SumerSports unless stated otherwise.
Raiders TE Brock Bowers vs. Bills: 79.5 Rec Yards
- TE Brock Bowers has posted at least 86 receiving yards in each of his first three games of the season.
- Bowers has quickly become the go-to target for the Las Vegas Raiders, earning the highest target share (29.8%) among all TEs.
- Out of 22 TEs with 20+ targets, Bowers has the third-most yards per reception (13.0) and most yards per route run (2.79).
- The Buffalo Bills’ defense is 28th in dropback EPA (0.26) and 29th in dropback success rate (52.5%) allowed, per RBSDM.
Pick Brock Bowers + Raiders to cover the spread on PrizePicks!
Rams WR Puka Nacua vs. Cardinals: 10.5 Rec Targets
- WR Puka Nacua has garnered 11 or more targets in two straight games since returning from injury.
- Nacua's registering the second-highest target share (34.4%) among all WRs.
- Through the first five weeks, the Los Angeles Rams are second in neutral pass rate (62.3%).
- That bodes well for the Rams, with the Arizona Cardinals sitting at 31st in dropback EPA (0.37) and 25th in dropback success rate (48.5%) allowed.
Pick Puka Nacua + Rams to win on PrizePicks!
Steelers WR Germie Bernard vs. Buccaneers: 4 Recs
- With WR Roman Wilson exiting early and WR Michael Pittman Jr. on injured reserve, rookie WR Germie Bernard produced season highs in targets (9), receptions (6), and receiving yards (80) against the Indianapolis Colts in Week 5.
- Wilson is set to miss multiple weeks for the Pittsburgh Steelers, allowing Bernard to potentially remain heavily involved in the passing attack.
- The Steelers are trusting QB Aaron Rodgers plenty, residing at fourth in neutral pass rate (60.0%) entering Week 6.
- The Tampa Bay Buccaneers are a pass-funnel defense, ranking 16th in dropback success rate (46.6%) and seventh in rushing success rate (35.2%).
Pick Germie Bernard + Steelers to cover the spread on PrizePicks!
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Giants TE Isaiah Likely vs. Saints: 52.5 Rec Yards
- TE Isaiah Likely has notched 66+ receiving yards in three of his first five starts.
- Likely is coming off season-high marks in targets (13), receptions (11), receiving yards (94), and receiving TDs (2).
- Only Bowers has a higher target share than Likely (29.5%) at the TE spot thus far.
- The New Orleans Saints’ defense is 26th in dropback EPA (0.17) and 28th in dropback success rate (51.1%).
Pick Isaiah Likely + Giants to win on PrizePicks!
Titans RB Tony Pollard vs. Colts: 54.5 Rush Yards
- Even in a below-average Tennessee Titans offense, RB Tony Pollard has achieved at least 64 rushing yards in two of his last four starts.
- RB Tyjae Spears has been inefficient as the backup, and he’s been unable to practice leading up to Sunday’s game against the Indianapolis Colts.
- After five weeks of action, the Colts’ defense is 32nd in rushing EPA (0.02) and 31st in rushing success rate (44.3%) allowed.
- Furthermore, Indy’s defense has let a RB rush for 101 or more yards in three of five games.
Pick Tony Pollard + Titans to cover the spread on PrizePicks!
Make Week 6 NFL Picks on PrizePicks
Targeting favorable matchups is typically a strategy to deploy when looking at player projections on PrizePicks. Among all the options in Week 6, the quintet of Bowers, Nacua, Bernard, Likely, and Pollard stands out.
Ahead of Sunday’s action, it's time to lock in your NFL Week 6 picks on PrizePicks. Just pick your players, predict More or Less on their stats, and cash in on your predictions when you're right.
With PrizePicks Team Picks, make your predictions on NFL game winners, spreads, and over/unders — or combine one with players for even higher payouts.
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