Best NFL Anytime TD Scorer Predictions for Week 6 – Jaylen Warren, More

NFL Week 6’s start didn’t feature much scoring, as the Denver Broncos mustered all of 17 points to the Seattle Seahawks’ 14 in overtime on Thursday Night Football. Despite that, the football world anticipates plenty of touchdowns over the next several hours and especially in prime time.

From afternoon and early evening into the night, there are matchups between stingy defenses, high-powered offenses, and everything in between. Which games stand out as potential avenues for the game’s high-profile talents to land TDs?

Below, we'll highlight our best NFL Anytime TD scorer predictions for PrizePicks in NFL Week 6, including five players who could reach the end zone.

Make your NFL Anytime TD picks for Week 6 on PrizePicks now.

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Best Week 6 NFL Anytime TD Scorer Picks for PrizePicks

In the early window, the Baltimore Ravens being down to their backup QB still may not stop one of the game’s ascending wideouts from achieving success.

Later on, the best RB to this point in the young season aims to keep the line moving, and both Sunday and Monday Night Football leave the door open for high point totals.  

Anytime TDs on PrizePicks include rushing, receiving, recoveries, and returns. PrizePicks often list Anytime TDs as Demons and Goblins, meaning users can only select "More." For standard projections, users can select “More” or “Less.”

Demons are tougher to win but are the only way to get higher payouts. Meanwhile, Goblins are lower than a standard projection, but they are easier to win, so there’s a lower payout.

Here are the top NFL Week 6 Anytime TD scorer picks to target this weekend, headlined by Zay Flowers, Jaylen Warren, Kenneth Walker III, Christian Watson, and Mike Evans.

Ravens vs. Browns Anytime TD Scorer Prediction – 1 p.m. ET

Ravens WR Zay Flowers: 1.5 Anytime TDs (Demon)

• Flowers is posting career-best figures for yards per game (101.3), catch rate (83.9%), yards after contact per reception (7.0), and more.
• Even with backup Tyler “Snoop” Huntley under center in Week 5, the 26-year-old was targeted 9 times and had 8 catches vs. the Atlanta Falcons. 
• The former first-round pick has been particularly dominant against single-high coverage (4.79 yards per route run) and man coverage (4.05 YPRR). Per Zain Dhanani, Cleveland leads the sport in both forms of coverage.
• No receiver was more successful out of the slot than Flowers in Weeks 1-5; he produced over 20 targets and a YPRR mark just over 6.0. 
• Flowers owns a top-three success rate entering Sunday’s play with a 71% figure, trailing only Tampa Bay Buccaneers WR Mike Evans and his own teammate Rashod Bateman.

Add Zay Flowers + Ravens to cover the spread to your PrizePicks lineup now.

Steelers vs. Buccaneers Anytime TD Scorer Prediction – 1 p.m. ET

Steelers RB Jaylen Warren: 1.5 Anytime TDs (Demon)

• Warren has 20+ touches in three consecutive games, averaging 8.0 yards per touch from scrimmage during that span. 
• Prior to Thursday Night Football, Warren ranked third leaguewide with 640 scrimmage yards. The two players in front of him, Atlanta Falcons RB Bijan Robinson and Detroit Lions RB Jahmyr Gibbs, had 43 and 31 more touches than him.
• Warren has the best combination of yards after contact and missed tackles forced per attempt over the last four seasons, via Scott Barrett. 
• According to SumerSports, Warren is ninth among all RBs in target share (14.94%) and seventh among RBs with 50+ rushes in EPA/carry (0.04). 
• Via NFL Pro, Tampa Bay cedes the 11th-highest success rate on targets to RBs (45.2%). Warren is netting 8.8 yards per target, third for RBs with 10 or more balls thrown their way.

Add Jaylen Warren + Steelers to win to your PrizePicks lineup now.

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Chargers vs. Chiefs Anytime TD Scorer Prediction – 4:25 p.m. ET

Chiefs RB Kenneth Walker III: 0.5 Anytime TDs (Goblin)

• Heading into Week 6, Walker leads the sport in yards per attempt (6.2) and per game (134.3) while recording at least 20 touches in every contest thus far. 
• Walker’s 42.4% missed tackle forced rate tops all ball carriers with at least 25 touches on the year.
• The reigning Super Bowl MVP records 4.22 yards after contact for each tote, easily a personal best (Pro Football Focus).
• Good luck selling out to stop Walker. He produces a video game-like 7.31 yards per attempt with 3 TDs when defenses bring 8+ players in the box.
• Per RBSDM, the Chargers’ run defense is 14th in EPA/carry (-0.119) and 18th in success rate (39.6%). 

Add Kenneth Walker III + Chiefs to cover the spread to your PrizePicks lineup now.

Cowboys vs. Packers Anytime TD Scorer Prediction – Sunday Night Football

Packers WR Christian Watson: 0.5 Anytime TDs (Demon)

• Watson may have just turned in his best game as a pro, logging 6 catches for 143 yards and a pair of scores vs. the Chicago Bears. He finished in the 99th percentile in air yards on targets and the 98th percentile in YPRR.
• Via 4for4, Watson’s received 71.0% of Green Bay’s red-zone targets, as well as 28.6% of their throws inside the 5-yard line. His 3 red-zone TDs are tied for third.
• Watson is one of just three Packers and the first since 1956 to ever record 400+ receiving yards and 6+ TDs in a season’s first five games, per NFL Researcher.
• Over the last three seasons, only Seattle Seahawks WR Jaxon Smith-Njigba and Los Angeles Rams WR Puka Nacua have a better YPRR mark than Watson’s 2.77.
• The Cowboys are surrendering 9.7 yards per target and a 5.9% TD rate to the WR position.

Add Christian Watson + Packers to win to your PrizePicks lineup now.

Commanders vs. 49ers Anytime TD Scorer Prediction – Monday Night Football

49ers WR Mike Evans: 0.5 Anytime TDs

• Evans has scored a TD in two of his last three games, seeing his targets and receptions jump from 6 to 8 to 10 and 3 to 5 to 7, respectively. 
• Despite being on the back nine of his career, Evans remains effective downfield. He’s accounted for a 71.0% air yard share in 2026.
• When targeting Evans this season, QB Brock Purdy is producing 11.9 yards per attempt with 4 TDs and a 149.9 passer rating.
• With the 49ers owning football’s fifth-highest pass rate over expected — 2.9%, via nfelo — there could be ample opportunities for Evans on MNF.
• Washington’s defense is 25th in dropback EPA/play (0.157) and 27th in dropback success rate (51.1%) given up. 

Add Mike Evans + 49ers to cover the spread to your PrizePicks lineup now.

Make NFL Week 6 Picks on PrizePicks

From the start of the London Game until the conclusion of Monday Night Football, what’s left of Week 6 figures to bring plenty of fireworks in the NFL world. Will one of these five standout players sniff pay dirt, or could it be an unsung hero who propels his team to victory?

Don’t wait until kickoff — make your NFL Week 6 picks on PrizePicks now and earn real money if you’re right.

Pick players, predict More or Less on their stats (like Anytime TDs), and cash in if you’re right. With Team Picks, you can make predictions on NFL game winners, spreads, and over/unders, now available in 36 states.

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