Best NFL Anytime TD Scorer Predictions for Afternoon Games – Davante Adams, More

Week 6’s late window features three games, two of which include totals exceeding 50 points. The three favorites all rank inside the top four in yards per game this season. Which star players will find the end zone this afternoon?

Below, we'll highlight our best NFL anytime TD scorer predictions for games kicking past 4:00 p.m. ET in NFL Week 6, including three players who could reach the end zone for picks on PrizePicks.

Make your NFL Anytime TD picks for Week 6 on PrizePicks now.

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Best Week 6 NFL Anytime TD Scorer Picks for PrizePicks

Today’s late window has three games: Cardinals vs. Rams, Chargers vs. Chiefs, and Bills vs. Raiders. The Rams’ matchup (51.5-point total) and the Raiders’ matchup (53.5-point total) feature two of the day's highest over/unders, so there should be no shortage of touchdowns this afternoon.     

Anytime TDs on PrizePicks include rushing, receiving, recoveries, and returns. PrizePicks often list Anytime TDs as Demons and Goblins, meaning users can only select "More." For standard projections, users can select “More” or “Less.”

Demons are tougher to win but are the only way to get higher payouts. Meanwhile, Goblins are lower than a standard projection, but they are easier to win, so there’s a lower payout.

Here are the top NFL Week 6 anytime TD scorer picks to target this weekend, headlined by Davante Adams, Kenneth Walker III, and Brock Bowers.

Cardinals vs. Rams Anytime TD Scorer Prediction – 4:05 p.m. ET

Rams WR Davante Adams: 0.5 Anytime TDs 

• After crushing it in Weeks 2 and 3 as the Rams’ top wideout, Adams has once again taken a backseat to a healthy WR Puka Nakua. However, he’s resumed the fruitful red zone role that helped him score 14 touchdowns in 2025.
• Per FantasyPros, Adams leads the team with 7 red zone targets, and 5 of them have come over the last two weeks with Nacua active. He scored 2 touchdowns in Week 5.
• Even with a less prominent overall role alongside his star teammate, Adams has still averaged 8.0 targets over the past two games in a pass-heavy offense. QB Matthew Stafford is averaging a league-high 43.2 pass attempts per game, and the team ranks fifth in pass rate over expected, per Sharp Football Analysis.
• The Cardinals are allowing the most points per game this season (32.4). They’ve struggled to defend the pass, ranking 31st in dropback EPA/play allowed (0.370), according to RBSDM.
• Arizona has given up the most touchdowns to wide receivers this year (10), per Pro Football Reference.    

Add Davante Adams + Rams to cover the spread on PrizePicks.

Chargers vs. Chiefs Anytime TD Scorer Prediction – 4:25 p.m. ET

Chiefs RB Kenneth Walker III: 0.5 Anytime TDs (Goblin)

• Walker has scored 6 total TDs across the Chiefs’ four games. Per PlayerProfiler, he’s seen the league’s third-most red zone touches (23) despite Kansas City already having their bye week.
• With the Chiefs’ wide receiver corps banged up, the offense could decide to lean even more on Walker. As is, he’s averaging 21.8 carries and 4.75 targets per game, helping him to a league-best 155.3 scrimmage yards per game.
• Among running backs with at least 30 carries, Walker is averaging the second-most yards after contact per attempt, according to PFF. He leads the league in missed tackles forced (39) and has the third-most runs for 10+ yards (14).
• The Chargers’ defense has been mediocre against the run, ranking 14th in rush EPA/play allowed (-0.119) and 18th in success rate (39.6%).
• The Chiefs are 7.5-point favorites, and the winless Chargers are plagued by injuries on both sides of the ball. Walker could benefit from a positive game script if Kansas City can get out to a big lead.

Add Kenneth Walker + Chiefs to win on PrizePicks.

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Bills vs. Raiders Anytime TD Scorer Prediction – 4:25 p.m. ET

Raiders TE Brock Bowers: 0.5 Anytime TDs

• Bowers leads the Raiders with a 29.8% target share, per SumerSports. He’s averaging 11.7 targets, 8.0 receptions, and 105.0 yards per game.
• The star tight end has scored a TD in all three weeks he’s played. He already has 6 red zone targets despite being inactive in Weeks 1 and 2.
• Among all pass-catchers with at least 30 targets this season, Bowers ranks eighth in yards per route run (2.79). That puts him ahead of guys like WR Chris Olave, WR Parker Washington, and WR Tee Higgins. 
• The Bills have allowed the fifth-most points per game (28.2) and second-most passing yards per game (280.4). They’re 28th in dropback EPA/play allowed (0.258) and 29th in dropback success rate (52.5%).
• Buffalo is one of four teams to already allow 13 or more passing touchdowns through five weeks. Raiders QB Kirk Cousins is tied for second in passing touchdowns (12).

Add Brock Bowers + Raiders to cover the spread on PrizePicks.

Make NFL Week 6 Picks on PrizePicks

A pair of potential shootouts in Los Angeles and Las Vegas could lead to a plethora of points in the late window on Sunday. Which players will find the end zone?

Don’t wait until kickoff — make your NFL Week 6 picks on PrizePicks now and earn real money if you’re right.

Pick players, predict More or Less on their stats (like Anytime TDs), and cash in if you’re right. With Team Picks, you can make predictions on NFL game winners, spreads, and over/unders, now available in 36 states.

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