The second half of the NFL season is well underway, and Week 10 presents plenty of high-profile matchups to choose from.
Whether it be a pair of bitter division rivals, a feisty inter-conference bout, a potential playoff preview or anything in between, this week is shaping up to be entertaining. With that comes touchdown opportunities for stars around the league.
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Week 10 NFL TD Scorer Predictions
With PrizePicks’ NFL Free2Play $1M jackpot game, you can make Week 10 TD scorer predictions and win rewards if you’re right. This week’s targets to consider are headlined by WR Zay Flowers, RB Kyren Williams and more.
Texans vs. Jaguars TD Scorer Prediction – 1:00 p.m. ET
Texans WR Nico Collins
- Despite QB C.J. Stroud being out due to a concussion, WR Nico Collins still makes ample sense as a potential pick for Week 10.
- Collins, who missed Week 8, has 10 and 11 targets in his last two games played.
- The star WR has scored a TD in three of his last four games against the Jaguars. He has 46 targets, 35 catches, and 478 yards in that span.
- Jacksonville is tied for the sixth-most TDs yielded to WRs this season with 10.
Vikings vs. Ravens TD Scorer Prediction – 1:00 p.m. ET
Ravens WR Zay Flowers
- Dating back to Week 4’s 37-20 loss to the Chiefs, Flowers has logged 5 or more receptions in each game on 88.8% of snaps played.
- Flowers has the fifth-most catches without a drop this year at 46, via Pro Football Focus.
- Per FantasyPros, Flowers has a 31.3% target share with 3.29 yards per route run against the blitz. Minnesota blitzes more than all but one NFL team.
- The Vikings give up the league’s most yards per target (11.6) against opposing WR1s, courtesy of Sharp Football Analysis.
Seahawks vs. Cardinals TD Scorer Prediction – 4:05 p.m. ET
Cardinals WR Marvin Harrison Jr.
- Marvin Harrison Jr. found his way into last week’s article, and he also found the end zone on Monday Night Football against the Cowboys. Why not run it back?
- QB Kyler Murray going to injured reserve might not hurt Harrison. The star WR averages just 42 yards and 10.5 yards per catch with Murray this year, as opposed to 62 and 16.9, respectively, with Jacoby Brissett.
- In Week 4’s meeting against the Seahawks, Harrison had a season-high 10 targets with 66 yards and a TD.
- Harrison’s 40% target rate in the red zone is tied for 20th among all WRs, per FantasyPros.
49ers vs. Rams TD Scorer Prediction – 4:25 p.m. ET
Rams RB Kyren Williams
- Williams failed to catch a single pass in Week 9’s 34-10 drubbing of the Saints, but his 25 carries for 114 yards both marked season-highs. He had a TD in the outing.
- Although he fumbled Week 5’s 26-23 game away, Williams had a pair of TDs against the 49ers, with both being through the air.
- Williams ranks 13th out of 104 RBs with a 72.7% rush share in the red zone.
- San Francisco is a middle-of-the-pack defense against RBs, ranking 18th in most fantasy points allowed. They’ve yielded more receptions to the position than all but two teams.
Commanders vs. Lions TD Scorer Prediction – 4:25 p.m. ET
Lions WR Amon-Ra St. Brown
- Amon-Ra St. Brown is averaging 10.5 targets, 8 receptions and 82 yards in his last four games.
- Per SumerSports, St. Brown’s 32.03% target share ranks fifth among all WRs.
- St. Brown is tied with Broncos WR Troy Franklin for the most catches in the red zone (11). He’s also in a four-way tie for receptions inside the 10-yard line (6).
- While Washington is 14th in most targets allowed to WRs (160), they’re tied for the fourth-most TDs surrendered with 11.
Chargers vs. Steelers TD Scorer Prediction: Sunday Night Football
Chargers TE Oronde Gadsden II
- Dating back to Week 6, Oronde Gadsden has hauled in 24 passes on 27 targets. He scored TDs in back-to-back games against the Colts and Vikings.
- The standout rookie TE averages the fourth-most yards per route run among players at his position with 100+ chances, per SumerSports.
- According to NFL Pro, Gadsden’s 8.5 average air yards per target ranks third among TEs with 30+ targets.
- The Steelers are tied with the Jets, Jaguars, Dolphins and Commanders for second-most TDs allowed to opposing TEs (6).
Packers vs. Eagles TD Scorer Prediction: Monday Night Football
Eagles WR A.J. Brown
- After sitting out Week 8 due to a hamstring injury and resting during the Week 9 bye, A.J. Brown appears primed to make his return on Monday Night Football.
- In his last active game this season, Brown turned in his best effort, going for 121 yards and 2 TDs against the Vikings.
- Among WRs with 100+ routes run, Brown’s 27.27% target share ranks 11th. His Eagles teammate, DeVonta Smith, sits right behind him at 26.57%.
- Via NFL Pro, Brown ranks second out of 36 WRs with 50+ overall targets in deep-pass target rate (21.6%). The Packers have faced the 14th-most such attempts.
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