Uzbekistan vs. Colombia Prediction, Picks, Lineups for World Cup 2026

Uzbekistan is set to make its World Cup debut against one of South America’s best in a Group K opener on Wednesday evening. Colombia will look to spoil the occasion as Los Cafeteros return to the World Cup after missing out in 2022. 

Entering the match, Colombia is heavily favored on PrizePicks Team Picks and returns a 1.35x payout with a Wednesday victory.

Below, we’ll break down our Uzbekistan vs. Colombia prediction and picks for Wednesday night’s World Cup 2026 match, including the spread, total goals, and key player picks for PrizePicks.

Make your Uzbekistan vs. Colombia prediction and World Cup picks on PrizePicks now!

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Uzbekistan vs. Colombia World Cup 2026 Prediction, Spread, Over/Under – Wednesday, June 17

How to watch Uzbekistan  vs. Colombia: FS1 & Fox One (English) | Telemundo & Peacock (Spanish)

Kickoff Time: 10:00 p.m. ET

Venue: Estadio Azteca, Mexico City, Mexico

Group: Group K

Colombia performed well in its final pre-tournament friendlies and will open the competition with some confidence, facing a team with no experience on the biggest stage.

The Colombian attack, led by Luis Díaz, has looked sharp heading into the tournament and will be the focal point of Néstor Lorenzo's game plan. 

Uzbekistan, by contrast, will likely sit in a low block, with the midfield dropping to form a back five when out of possession. The Central Asian side relies heavily on the counter, with their compact defensive structure serving as the foundation of their approach.

Fabio Cannavaro's side may not create many chances but will look to make the most of the ones they do get. 

Uzbekistan vs. Colombia: Favorite to Win, Spread, Total Goals – Wednesday, June 17

Colombia enters Wednesday’s game as the favorites, returning a 1.35x payout if they win outright, via PrizePicks Team Picks.

Meanwhile, Uzbekistan aims to limit Colombia’s rapid counters that typically lead to one-on-one opportunities for their elite attackers. Look for Uzbekistan to potentially avoid playing out from the back and to limit Colombia’s high press.

Here are the full payouts for the Uzbekistan vs. Colombia match on PrizePicks.

• Winner Payout: Uzbekistan – 7.69x | Tie – 4.34x | Colombia – 1.35x
• Spread: Colombia -1.5 (2.04x Payout) 
• Total Goals: 2.5 (Over – 2x)
• Both Teams to Score: Yes 1.85x | No 1.85x

Payouts show potential returns on correct Team Picks predictions. A 2x payout returns $200 on a $100 entry. Lower multipliers reflect outcomes users are picking as more likely. Payouts are live as of writing and subject to change.

Make your Uzbekistan vs. Colombia prediction on spread or goals on PrizePicks Team Picks — available in 35 states!

Uzbekistan vs. Colombia Prediction on Total Goals for World Cup 2026 

Here are the key stats and trends for Uzbekistan vs. Colombia before making your World Cup 2026 predictions on PrizePicks.

• Colombia has scored 2+ goals in four of its last six friendlies leading up to the tournament. They finished as the second-highest goal-scoring team in CONMEBOL qualifiers.
• Lorenzo’s attack relies heavily on distribution from the midfield, leading attackers into dangerous areas. Colombia assisted on 22 of 28 total goals scored in the qualifiers.
• Uzbekistan conceded 11 goals in 16 matches in the AFC World Cup qualifiers. The White Wolves kept a clean sheet in four of their final five matches of the competition.
• Cannavaro’s side struggled in its final two pre-tournament friendlies, conceding 2 goals in back-to-back matches against Canada and the Netherlands. The sides combined for 5.03 xG on Uzbekistan.
• Colombia created 2.8 big chances per game in its final five friendlies leading up to the tournament. Los Cafeteros won three of the five matches with a combined xG of 8.58.

Lock in your Uzbekistan vs. Colombia prediction for the 2026 World Cup now!

Uzbekistan vs. Colombia Lineups for World Cup 2026 – Wednesday, June 17

Here are the projected Uzbekistan vs. Colombia lineups for today's World Cup match. Lineups are not official and are based on historical data.

Uzbekistan Lineup vs. Colombia Today

Projected Formation: 3-4-2-1

• Goalkeeper: Abduvokhid Nematov
• Defense: Abdukodir Khusanov, Rustam Ashurmatov, Abdulla Abdullaev
• Midfield: Sherzod Nasrullaev, Otabek Shukurov, Odiljon Khamrobekov, Farrukh Sayfiev
• Forwards: Abbosbek Fayzullaev, Eldor Shomurodov, Oston Urunov

Colombia Lineup vs. Uzbekistan Today

Projected Formation: 4-1-3-1

• Goalkeeper: Camilo Vargas
• Defense: Johan Mojica, Jhon Lucumí, Davinson Sánchez, Daniel Muñoz
• Midfield: Gustavo Puerta, Jefferson Lerma, James Rodríguez
• Forwards: Luis Díaz, Jhon Arias, Luis Javier Suarez

Uzbekistan vs. Colombia Picks, Player Stats for World Cup: 06/17/26

Here are the top Uzbekistan vs. Colombia player picks to target on Wednesday, June 17. Today’s World Cup 2026 picks are headlined by Luis Díaz, James Rodríguez, and Abdukodir Khusanov.

Colombia FW Luis Díaz Pick vs. Uzbekistan  

Luis Díaz Projections via PrizePicks: 0.5 Shots on Target (Goblin), 3 Shots, 1.5 Fouls Drawn (Goblin)

• Díaz led Colombia with 1.2 shots on target per game during the qualifiers. He has had at least 1 SOT in three straight matches that he has played over 70 minutes in.
• The Bayern Munich star averaged just over 3 shots per game during the qualifiers and 2.8 per game in the Bundesliga. Díaz has had 3+ total shots in two of his last five appearances for his country.
• Díaz drew just under 2 fouls per game during Colombia’s Copa America runner-up campaign last year. Colombia’s star winger has been fouled 10 times in his last four friendlies combined.

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Colombia MF James Rodríguez vs. Uzbekistan  

James Rodríguez Projections via PrizePicks: 46.5 Passes Attempted, 0.5 Assists (Demon), 3.5 Shots Assisted

• Rodríguez enters his third World Cup as Colombia’s primary playmaker in his attacking midfielder position. He attempted 48+ passes in his final two pre-tournament friendlies despite playing under 65 minutes in both games.
• The veteran midfielder has provided 4 assists in his last four games for both club and country. Rodríguez led Colombia with 7 assists during World Cup qualifiers and has 4 assists in eight career World Cup games. He also had 6 assists in six matches during Colombia’s most recent Copa America run.
• Rodríguez averaged 3.2 key passes per contest during qualifiers and 3.3 during the Copa America. He averaged 2.6 key passes per game during his first World Cup in 2014.

Combine Colombia + James Rodríguez World Cup picks for bigger payouts on PrizePicks.

Uzbekistan DF Abdukodir Khusanov vs. Colombia 

Abdukodir Khusanov Projections via PrizePicks: 5.5 Clearances, 41.5 Passes Attempted, 2 Tackles

• The Manchester City star is averaging just 4 clearances per game over his last five matches for his country. Khusanov had 6+ clearances only once in that span.
• Similarly, Khusanov has had 42 or more passes in two of his last five appearances. With Uzbekistan struggling to keep possession outside of Asia, the White Wolves hardly play from the back to avoid being pressed deep into their own end.
• Khusanov has 12 combined tackles in his last four friendlies leading up to the tournament. He averaged 1.3 in limited minutes at Man. City this past season.

Combine Uzbekistan + Abdukodir Khusanov World Cup picks for bigger payouts on PrizePicks.

Make Your Uzbekistan vs. Colombia Prediction for World Cup on PrizePicks

Colombia looks to impose its will as it hopes to spoil Uzbekistan’s first-ever World Cup match later this evening. Uzbekistan, meanwhile, hopes to fend off Colombia’s relentless attack for as long as possible and try to convert on any chances.

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