The Oklahoma City Thunder (62-16) look to stay hot as they take on a shorthanded Los Angeles Lakers (50-28) squad on the road.
Oklahoma City and Los Angeles have faced off three times this season, with the Thunder winning all three meetings. The Thunder are 17.5-point favorites on PrizePicks Team Picks in a showdown that tips off at 10:30 p.m. ET on Tuesday.
Below, we’ll break down our Thunder vs. Lakers prediction on the spread for Tuesday’s game. Make your NBA picks on PrizePicks and PrizePicks Team Picks and earn real money if you’re right, including on game winners, spreads, and totals!
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Thunder vs. Lakers Prediction, Spread, Over/Under
The Thunder are just two wins away from clinching the No. 1 seed in the Western Conference. Oklahoma City, currently riding a five-game winning streak, holds a 2.5-game lead over the San Antonio Spurs for first place in the West.
Oklahoma City has dealt with injuries to several of its key players throughout the 2025-26 season but is getting healthy at the right time. F Jalen Williams recently returned to the lineup, although the team is being cautious with his hamstring injury. He'll sit out Tuesday’s contest.
Meanwhile, the Lakers were dealt a few brutal injury blows over the last several days. PG Luka Doncic suffered a Grade 2 hamstring strain against the Thunder last week and will be out through the remainder of the regular season. In addition, SG Austin Reaves will miss four to six weeks with an oblique injury.
The Lakers currently have a chance of earning the third seed in the Western Conference, sitting just a half-game behind the Denver Nuggets.
Oklahoma City won and covered the spread in each contest against L.A. this season.
Thunder vs. Lakers Spread, Over/Under
The Thunder enter Tuesday’s game as 17.5-point favorites, returning a 1.03x payout on PrizePicks Team Picks if they win outright.
The Lakers are underdogs with a 10x payout if they win, via PrizePicks Team Picks, where you can earn money with your picks in 35 states.
- Spread: Oklahoma City Thunder -17.5
- Over/Under: 221.5
- Game Winner Payout: Thunder 1.03x | Lakers 10x
Team Picks data is live at the time of writing and is subject to change.
Thunder vs. Lakers Prediction on Spread – 4/7/26
Here are the key stats to know before locking in your Thunder vs. Lakers prediction on the spread for Tuesday, April 7, on PrizePicks.
- The Thunder are 17-18 against the spread as road favorites, producing a 48.6% cover rate. However, Oklahoma City is 5-1 ATS in its last six meetings vs. Los Angeles.
- The Lakers are 2-6 ATS over their last eight games and are just 7-7 ATS without Doncic overall.
- Oklahoma City owns the fourth-best field goal percentage (48.4%).
- The Thunder allow just 11.9 fastbreak points per contest, which ranks first in the NBA.
- According to NBA Advanced Stats, the Thunder boast the league’s top defensive rating (106.0). Meanwhile, the Lakers have a 116.0 mark, which ranks 20th among NBA teams.
- Oklahoma City leads the sport with an average scoring differential of +11.6, while Los Angeles ranks 15th at +1.4.
- During their current five-game winning streak, the Thunder are shooting 39.7% from deep, a significant increase over their 36.3% season average.
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Make Thunder vs. Lakers Picks on PrizePicks
The Thunder aim to move one step closer to clinching the top seed in the Western Conference, while the Lakers try to remain competitive without Doncic and Reaves.
You can make your Thunder vs. Lakers picks on PrizePicks and PrizePicks Team Picks and earn real money. Just pick players, predict More or Less on their projected stats, and cash in if you’re correct. With Team Picks, make predictions on winners, spreads, and over/unders, now available in 35 states.
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