Although the 2026 NBA playoffs are under a month away, there’s still plenty to sort out in the standings. That rings true in both the Western Conference and Eastern Conference, and Monday night’s Oklahoma City Thunder vs. Philadelphia 76ers bout impacts each squad.
The 7:00 p.m. ET clash sees the defending champs hit the road and take on a team looking to get out of play-in territory. Oklahoma City is a massive road favorite, as Philly is without two of its best players.
Below, we’ll break down our Thunder vs. 76ers prediction and picks for Monday night’s game. Make your NBA picks on PrizePicks and PrizePicks Team Picks and earn real money if you’re right, including on game winners, spreads, and totals!
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Thunder vs. 76ers Prediction, Spread, Over/Under
Gone are the days of the Thunder chasing the regular-season wins record, but it’s still been a very productive campaign for head coach Mark Daigneault’s crew. Oklahoma City has overcome numerous injuries to be 56-15 entering Monday’s game, good for the top seed out West.
It hasn’t exactly been a similar path for the 76ers, but injuries are a theme for them as well. Even with the roster at less than full strength all year, Philadelphia is 39-32, currently slotted into the No. 7 spot in the East. Seed Nos. 5 through 10 are separated by a mere 2.5 games.
The Thunder and 76ers have met 148 times in the regular season. OKC owns a narrow 75-73 series lead, including three consecutive wins dating back to 2025.
Thunder vs. 76ers Spread, Over/Under
The Thunder enter Monday’s game as 15.5-point road favorites, returning a 1.07x payout on PrizePicks Team Picks if they win outright.
The 76ers are home underdogs with an 8.33x payout if they win, via PrizePicks Team Picks, where you can earn money with your picks in 35 states.
- Spread: Oklahoma City Thunder -15.5
- Over/Under: 225.5
- Game Winner Payout: Thunder 1.07x | 76ers 8.33x
Team Picks data is live at the time of writing and is subject to change.
Thunder vs. 76ers Injury Report
Let’s dive into the full Thunder vs. 76ers injury report for Monday, March 23, via NBA.com.
Oklahoma City Thunder Injury Report
- G Ajay Mitchell (suspension): OUT
Philadelphia 76ers Injury Report
- PF-C Dominick Barlow (ankle): Doubtful
- C Joel Embiid (oblique): OUT
- F Paul George (suspension): OUT
- PG Tyrese Maxey (finger): OUT
Thunder vs. 76ers Prediction on Spread – 3/23/26
Here are the key stats to know before locking in your Thunder vs. 76ers prediction on spread for Monday, March 23 on PrizePicks.
- The Thunder are 31-37 against the spread as favorites, a middling mark relative to the rest of the NBA. Similarly, the 76ers’ 16-16 ATS mark as underdogs is nothing to write home about.
- Oklahoma City boasts the No. 1 average scoring margin in the Association at +11.1, also sitting fifth in scoring on offense at 118.7 points per game.
- OKC is even better on the defensive end, serving as the NBA’s best fastbreak defense (11.7 PPG) and second-best group in the paint (41.2 PPG).
- Philadelphia’s offense is solid, albeit unspectacular, ranking 14th in scoring (115.8 PPG) but fourth-worst in effective field goal percentage (52.8%).
- On defense, the 76ers allow the 17th-ranked points per shot at 1.155.
Thunder vs. 76ers Picks for PrizePicks Today: 3/23/26
Here are three top Thunder vs. 76ers picks to target for Monday, March 23 on PrizePicks. Player stat projections via PrizePicks are headlined by PG Shai Gilgeous-Alexander, C-PF Chet Holmgren, and SG VJ Edgecombe.
Thunder PG Shai Gilgeous-Alexander vs. 76ers Projection: 29.5 Points
- Gilgeous-Alexander averages 31.6 PPG on the year. Since returning from injury on February 27, that number is holding mostly steady at 30.9.
- Last year’s NBA MVP has leveled up his efficiency, posting a video game-like 66.5 true shooting percentage.
- No player accounts for more offensive win shares (10.0) than SGA, and his .333 win shares per 48 minutes also top the sport.
- Midrange mastery is the name of Gilgeous-Alexander’s game, as he’s making 47.8% of his attempts from 3-10 feet, 58.1% from 10-16 feet, and 49.6% from 16 feet to the 3-point line.
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Thunder C-PF Chet Holmgren vs. 76ers Projection: 24.5 Pts + Rebs
- In his fourth season, Holmgren averages 26.2 combined points and rebounds. That figure is 26.6 since the All-Star break.
- Holmgren is shooting new personal bests from 0-3 feet (80.6%) and 10-16 feet (47.6%).
- The former No. 2 overall NBA Draft pick owns career-high rates for offensive rebounding (7.4%), defensive rebounding (25.1%), and total rebounding (16.6%).
- According to FantasyPros, the 76ers give up 22.09 PPG and 14.67 RPG to the C position and rank even worse against PFs.
76ers SG VJ Edgecombe vs. Thunder Projection: 27.5 Pts + Rebs + Asts
- Edgecombe puts up 25.4 points, rebounds, and assists each night. Over his last seven contests, that ledger is up to a whopping 31.0.
- Via NBA RAPM, Edgecombe’s 20.5 shot usage puts him in the 79th percentile, and his 16.4 points per 75 possessions ranks in the 67th percentile.
- The former Baylor standout brings down 5.8% of his own misses and 11.5% of opposing missed shots.
- Per databallr, in minutes without Maxey on the court, the rookie’s usage rate climbs by 4.7%.
Make Thunder vs. 76ers Picks on PrizePicks
Thunder vs. 76ers picks for Monday night’s battle of the two conferences aren’t the only avenue hoops fans have to getting in on the daily NBA action.
You can make your picks on PrizePicks and PrizePicks Team Picks and earn real money. Just pick players, predict More or Less on their projected stats, and cash in if you’re correct. With Team Picks, make predictions on winners, spreads, and over/unders, now available in 35 states.
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