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Saquon Barkley Projections, Pick for Thursday Night Football

Eagles RB Saquon Barkley runs the football in an NFL game.
AP Photo/Matt Rourke

The stage is set for an epic NFC East clash as the Philadelphia Eagles face off against the New York Giants in Week 6. The game streams on Prime Video on October 9, with kickoff at 8:15 p.m. ET.

Eagles RB Saquon Barkley is expected to suit up for Thursday Night Football despite being limited in practice this week with a sore knee according to CBS. He didn’t suit up in last year’s Week 18 matchup, to stay fresh for the Eagles' Super Bowl run, but he left his mark earlier that season, torching the Giants for 176 yards on just 17 carries in Week 7.


Eagles RB Saquon Barkley Projection: 18.5 Longest Rush

  • Against the Giants in their previous meeting, Barkley recorded explosive runs of 55, 41, and 38 yards.
  • The Giants rank as the sixth-worst rush defense in the league, giving up 700 rushing yards over the first five weeks of the 2025 season. They've allowed five runs of 20+ yards and two runs over 40 yards, including a 54-yard dash by Chargers rookie Omarion Hampton, per NFL stats.
  • New York’s rush defense is the NFL's fourth-worst, surrendering 5.3 yards per carry. Barkley may not have hit a long run over 17 yards yet this season, but last year he smashed 17 runs over 20 yards and led the league with seven carries over 40 yards, per the NFL.
  • Given that this is the weakest rush defense the Eagles have faced this season, expect Saquon to build on his explosive performances from last year against the Giants, as not much has changed from New York’s defense against the run.

More Saquon Barkley Projections vs. Giants Tonight

All eyes are on Barkley as he faces the Giants in a highly anticipated NFC East Thursday Night Football matchup. PrizePicks has dropped his latest stat projections on the PrizePicks NFL board. Whether you're backing the More or leaning Less, now's your chance to make your picks and turn bold predictions into payouts.

Check out Saquon Barkley’s top projections for tonight’s Giants showdown, via PrizePicks.

  • 85.5 Rush Yards 
  • 0.5 Rush+Rec TDs (Goblin)
  • 15.5 Receiving Yards
  • 17 Fantasy Score
  • 2.5 Receptions
  • 17.5 Rush Attempts
  • 102.5 Rush+Rec Yards
  • 3.5 Yards on First Rush
  • 4.5 Yds First Rec
  • 9.5 Longest Reception

Make Thursday Night Football Picks on PrizePicks

Week 6 brings more than just Saquon Barkley — there's action across the league, and PrizePicks is ready for it. Jump into their NFL Free2Play contest and test your skills by predicting touchdown scorers from a variety of matchups.

Think you know football? Prove it! Pick More or Less on key player stats and turn your insight into real money every NFL Sunday.

Your go-to source for weekly predictions, player insights, and winning edge all season long — The Playbook by PrizePicks has you covered.

Get in the game! Sign up for PrizePicks and cash in on your sports predictions. Play $5 and get $50 instantly in Lineups with promo code PLAYBOOK.

about the author

JayWall is an NFL fantasy football expert for PrizePicks. He's a lifelong Philadelphia Eagles fan and fantasy football addict who's been playing since elementary school, diving into dynasty leagues since 2018. Trades are his favorite part of the game. After years of fantasy football obsession, he's finally started writing about his love for the game.

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