Following Tuesday’s thrilling play-in NCAA Tournament games, Wednesday has another doubleheader in store. The No. 16 Prairie View A&M Panthers (18-17) and the No. 16 Lehigh Mountain Hawks (18-16) begin the action in Dayton, Ohio, with a 6:40 p.m. ET tip-off on truTV.
Lehigh is a narrow 2.5-point favorite on the spread, per PrizePicks Team Picks. Who will advance in the South region bracket and face No. 1 Florida on Friday? Let’s make a Prairie View A&M vs. Lehigh prediction on the spread for Wednesday, March 18.
Make your college basketball picks on PrizePicks and PrizePicks Team Picks and earn real money if you’re right, including on game winners, spreads, and totals!
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Prairie View A&M vs. Lehigh Prediction, Spread, Over/Under
Tonight marks the first head-to-head matchup between the programs. Following conference tournament wins, each team comes in red-hot, as Prairie View A&M is 9-1 and Lehigh is 8-2 over the last 10 games.
The Panthers are a perfect 10-0 against the spread (ATS) in the split, while the Mountain Hawks sport a 7-3 ATS mark. Furthermore, Prairie View A&M is no stranger to low-scoring games, with the under 9-1 in the past 10 matchups.
Prairie View A&M vs. Lehigh Spread, Over/Under
Lehigh is favored by 2.5 points for CBB picks on PrizePicks Team Picks, where you can earn money with your picks in 35 states.
According to PrizePicks Team Picks, tonight’s total is 140.5 for the over/under.
- Spread: Lehigh Mountain Hawks -2.5
- Over/Under: 140.5
- Gamer Winner Payout: Prairie View A&M 2.38x | Lehigh 1.58x
Team Picks data is live at the time of writing and is subject to change.
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Prairie View A&M vs. Lehigh Prediction on Spread for NCAA Tournament – 3/18/26
Bart Torvik ranks the two neck and neck in efficiency, with Prairie View A&M 281st and Lehigh 284th. Both teams lean on their defense, as the Panthers are 303rd in adjusted offensive efficiency compared to the Mountain Hawks 287th.
Lehigh sits in the 43rd and 19th percentiles of 3-point and close-2 shot distributions. Shot distributions feature an opposite formula for the Panthers, ranked in the seventh and 45th percentiles for 3-pointers and close-2s.
Between the two defenses, Prairie View A&M could have the best matchup by ranking in the 95th percentile of 3-point shot distribution allowed while ceding only 19.4 attempted triples per contest (91st percentile). Lehigh is in the eighth percentile of close-2 shot distribution allowed, playing into the Panthers’ claws.
Prairie View A&M G Dontae Horne (31.7%) and G Tai’Reon Joseph (30.7%) each shoot low percentages from 3-point land. If Horne (20.2 PPG) and Joseph (18.2 PPG) can attack the rim at will, the Panthers may have a path to victory.
Make Prairie View A&M vs. Lehigh Picks on PrizePicks
After winning the SWAC Tournament as the No. 8 seed, Prairie View A&M is blazing hot headed into Wednesday night. Will the Panthers grab their first NCAA Tournament win vs. Lehigh?
Make your Prairie View A&M vs. Lehigh picks and NCAA Tournament predictions at PrizePicks and PrizePicks Team Picks, where you can earn real-money rewards for your predictions if you’re right.
Just choose players, predict More or Less on their projected stats, and follow the hoops action to see if your picks hit. You can make picks on winners, spreads, and over/unders on Team Picks, now available in 35 states.
Keep tabs on the Playbook for continued college basketball predictions, picks, and news all the way through the NCAA Tournament.



