With the 2025-26 regular season in the books, the NFL shifts focus to an absolutely loaded weekend of wild-card teams facing division champions.
As the 14-3 Denver Broncos and 14-3 Seattle Seahawks benefit from first-round byes, seed Nos. 2-7 in the AFC and NFC are in action from Saturday through Monday. With six games on the docket, there are ample opportunities to enjoy the action.
Below, we’ll dive into the full NFL wild card weekend schedule. With PrizePicks Team Picks, you can make predictions on game winners, spreads, totals, and futures and turn your NFL picks into real money if you’re right.
#5 Los Angeles Rams vs. #4 Carolina Panthers
Date: Saturday, Jan. 10
Time: 4:30 p.m. ET
Where to Watch: FOX
Rams vs. Panthers Spread, Over/Under, Game Winner Payout
Rams vs. Panthers over/under, spread, and game winner payouts are via PrizePicks Team Picks. All projections are live as of writing and are subject to change.
- Game Winner Payout: Rams 1.14x | Panthers 4.76x
- Spread: Rams -10.5
- Over/Under: 46.5
#7 Green Bay Packers vs. #2 Chicago Bears
Date: Saturday, Jan. 10
Time: 8:00 p.m. ET
Where to Watch: Prime Video
Packers vs. Bears Spread, Over/Under, Game Winner Payout
Packers vs. Bears over/under, spread, and game winner payouts are via PrizePicks Team Picks. All projections are live as of writing and are subject to change.
- Game Winner Payout: Packers 1.85x | Bears 1.85x
- Spread: Bears -2.5
- Over/Under: 46.5
#6 Buffalo Bills vs. #3 Jacksonville Jaguars
Date: Sunday, Jan. 11
Time: 1:00 p.m. ET
Where to Watch: CBS, Paramount+
Bills vs. Jaguars Spread, Over/Under, Game Winner Payout
Bills vs. Jaguars over/under, spread, and game winner payouts are via PrizePicks Team Picks. All projections are live as of writing and are subject to change.
- Game Winner Payout: Bills 1.81x | Jaguars 1.88x
- Spread: Bills -2.5
- Over/Under: 51.5
#6 San Francisco 49ers vs. #3 Philadelphia Eagles
Date: Sunday, Jan. 11
Time: 4:30 p.m. ET
Where to Watch: FOX
49ers vs. Eagles Spread, Over/Under, Game Winner Payout
49ers vs. Eagles over/under, spread, and game winner payouts are via PrizePicks Team Picks. All projections are live as of writing and are subject to change.
- Game Winner Payout: 49ers 2.56x | Eagles 1.47x
- Spread: Eagles -3.5
- Over/Under: 46.5
#7 Los Angeles Chargers vs. #2 New England Patriots
Date: Sunday, Jan. 11
Time: 8:00 p.m. ET
Where to Watch: NBC, Peacock
Chargers vs. Patriots Spread, Over/Under, Game Winner Payout
Chargers vs. Patriots over/under, spread, and game winner payouts are via PrizePicks Team Picks. All projections are live as of writing and are subject to change.
- Game Winner Payout: Chargers 2.56x | Patriots 1.47x
- Spread: Patriots -3.5
- Over/Under: 45.5
#5 Houston Texans vs. #4 Pittsburgh Steelers
Date: Monday, Jan. 12
Time: 8:00 p.m. ET
Where to Watch: ESPN, ESPN+, ABC (ManningCast on ESPN2, ESPN+)
Texans vs. Steelers Spread, Over/Under, Game Winner Payout
Texans vs. Steelers over/under, spread, and game winner payouts are via PrizePicks Team Picks. All projections are live as of writing and are subject to change.
- Game Winner Payout: Texans 1.51x | Steelers 2.43x
- Spread: Texans -3.5
- Over/Under: 39.5
Make NFL Wild Card Weekend Picks on PrizePicks
Whether it’s Rams vs. Panthers to kick off the weekend or Texans vs. Steelers to end the slate, you have a multitude of options to turn your NFL playoff predictions into rewards.
You can make your wild card weekend game picks on PrizePicks and PrizePicks Team Picks and earn real money. Just pick players, predict More or Less on their projected stats, and cash in if you’re correct. With Team Picks, make predictions on winners, spreads, and over/unders, now available in 30 states.
Keep it locked in here with the Playbook for continued NFL news, analysis, and picks.
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