It’s never too early to start thinking playoffs, and plenty of NFL teams can position themselves better for that in Week 6.
This weekend’s crop of games has everything ranging from potential postseason previews to squads that might be jockeying for positioning in April’s NFL Draft.
Here, we’ll dive into some of the top Week 6 TD scorer predictions for Sunday and Monday’s NFL slate.
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Week 6 TD Scorer Predictions
Lions RB Jahmyr Gibbs and Falcons WR Drake London headline our Week 6 TD scorer predictions for PrizePicks’ NFL Free2Play $1M jackpot game.
Steelers vs. Browns TD Scorer Prediction – 1 p.m. ET
Browns RB Quinshon Judkins
- Just four games into his rookie season, RB Quinshon Judkins is already up to 72 attempts, 347 yards, and 2 TDs.
- When the second-round pick is on the field, he’s receiving volume — a staggering 76.4% of touches, to be exact.
- Judkins sees plenty of stacked boxes but remains above-average in RYOE (rushing yards over expected).
- Of 29 NFL RBs with 50-plus carries, Judkins is second in rushing yards after contact per attempt (4.15), via Pro Football Focus.
- Despite being in the top 10 in fewest rushing yards allowed to RBs, the Steelers’ run defense is just 14th in EPA/play, per SumerSports.
Panthers vs. Cowboys TD Scorer Prediction – 1 p.m. ET
Panthers WR Tetairoa McMillan
- Entering Week 6, Panthers WR Tetairoa McMillan is the only NFL wideout with at least 350 receiving yards and 40 targets, but no TDs.
- McMillan has logged 8 or more targets in each game of his debut campaign.
- According to FantasyPros, McMillan’s red zone target share is 29.4%, the same as Rams star Puka Nacua.
- No team has allowed more TDs to WRs (10) than the Cowboys.
Saints vs. Patriots TD Scorer Prediction – 1 p.m. ET
Patriots WR Stefon Diggs
- Pats WR Stefon Diggs has the most receiving yards for a WR (359) without a receiving TD this season.
- After a slow start, Diggs might be back in form. The four-time Pro Bowler has gone for 6 or more catches and 100-plus yards in consecutive weeks.
- This is the first time Diggs has gone five consecutive games without a TD since the end of the 2023-24 regular season.
- Per NFL Pro, Diggs’ +17.4% catch rate over expected is a career-best mark.
- The Saints are tied for 11th-most with 5 TDs allowed to WRs.
Jaguars vs. Seahawks TD Scorer Prediction – 1 p.m. ET
Jaguars WR Brian Thomas Jr.
- Thomas exploded for 10 TDs as a rookie but is scoreless on 38 targets entering Week 6.
- According to Pro Football Focus, Thomas ranks in the top 25 among WRs in deep targets with 6.
- Thomas has upped his catch rate from 28% in Weeks 1-3 to 69% in Weeks 4-5, also going from a 4.6 yard-per-target average to 9.9.
- The Seahawks’ defense is cooling off, ranking 19th in EPA/play and 24th in EPA/pass.
Chiefs vs. Lions TD Scorer Prediction: Sunday Night Football
Lions RB Jahmyr Gibbs
- Gibbs led the sport with 20 combined TDs last year in what was just his second season — a testament to his nose for the end zone.
- Since not scoring in Week 1, Gibbs has a rushing or receiving TD in each of his 2025 contests.
- Among RBs with at least 4 receptions in the red zone, Gibbs’ target percentage of 85.7 is third, per FantasyPros.
- Courtesy of NFL Pro, Lions RBs have the most yards before contact (233) on designed runs this year.
- The Chiefs’ defense is football’s third-worst in EPA/rush.
Falcons vs. Bills TD Scorer Prediction: Monday Night Football
Falcons WR Drake London
- London is coming off his best game of the season — 8 catches for 110 yards and his first 2025 TD against the Commanders.
- Per Fantasy Points Data, London is sixth in the NFL in first-read target share inside the 10-yard line.
- The former No. 8 overall pick has the 11th-highest target share of WRs with 50 or more routes run at 28.5%, per SumerSports.
- The Bills have yielded 5 TDs to opposing WRs this year.
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