Mercury vs. Fever Prediction, Spread, WNBA Picks – Monday, June 22

The Phoenix Mercury (5-12) vs. the Indiana Fever (9-7) headline Monday, June 22’s four-game WNBA schedule, taking the spotlight on USA Network for an 8:00 p.m. ET tip-off. PrizePicks Team Picks tabs Indiana as a notable 7.5-point favorite on the spread.

Phoenix’s struggles have continued with a 1-4 record over its last five games. Meanwhile, the Fever come off back-to-back losses against the Dream. Who will get a much-needed rebound win on Monday night? 

Below, we'll break down our Mercury vs. Fever prediction and picks for Monday’s WNBA game, including the spread, over/under, and key player picks for PrizePicks. 

Make your Mercury vs. Fever picks on PrizePicks now!

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Mercury vs. Fever Prediction, Spread, Over/Under – Monday, June 22

According to WNBA.com, the Fever are around the middle of the league with a 3.6 net rating (seventh), while the Mercury hold a -4.1 net rating (11th). 

Indiana features a high-powered offense, with 92.4 points per game (first) and a 52.3% effective field goal percentage (fourth). That’s been overshadowed at times by surrendering 89.7 PPG (12th) and a 50.5 eFG% (eighth).

Phoenix sits 11th in offensive and defensive ratings, but it carries a few strengths on defense that could help limit the Fever’s attack. We’ll break down that matchup and more in our Mercury vs. Fever prediction.

Mercury vs. Fever Spread, Over/Under – Monday, June 22

After sitting in the underdog role in their last two games, the Fever are favored by 7.5 points tonight, paired with a 1.29x payout to win vs. the Mercury.

Here are the full payouts for the Mercury vs. Fever game on PrizePicks.

• Spread: Indiana Fever -7.5 (1.88x payout)
• Over/Under: 178.5 (1.92x payout on Over)
• Game Winner Payout: Mercury 3.22x | Fever 1.29x

Make your Mercury vs. Fever prediction on the spread or over/under on PrizePicks Team Picks — available in 35 states!

Team Picks data is live at the time of writing and is subject to change. 

Mercury vs. Fever Injury Report for Monday, June 22

Let’s look at the full Mercury vs. Fever injury report for Monday’s matchup, via WNBA.com.

Phoenix Mercury Injury Report

• G Monique Akoa Makani (hamstring): OUT
• G Sami Whitcomb (knee): OUT

Indiana Fever Injury Report

• G Caitlin Clark (back): Probable

Mercury vs. Fever Prediction on Spread – 6/22/26

Here are the key game stats and trends behind our Mercury vs. Fever prediction on the spread for Monday, June 22’s game.

• Phoenix has its flaws on defense, like allowing 9.6 made 3-pointers per game (15th), but it holds opponents to 35.2 paint points (fourth-fewest) and 17.9 free throw attempts per contest (the fewest).
• The Fever have dealt with shaky 3-point efficiency at times, partially due to G Caitlin Clark’s 33.3% 3-point percentage this season.
• Indiana regularly gets to the rim and draws fouls, recording 39.5 paint points (sixth-most) and 23.3 free throw shots per game (fourth-most). If the Mercury can limit both categories, will that lead to a lower score and tight margin? 
• The pace should play a major factor, as the Fever feature the league's quickest tempo compared to Phoenix’s third-slowest pace. Against a high-powered offense, the Mercury will likely look to slow the tempo.
• Winning the possession battle can help control the pace of a game, and Phoenix posts 14.1 turnovers per game (seventh-fewest) compared to Indiana’s 16.7 turnovers per contest (15th).
• The Fever are 2-5 against the spread (ATS) over the last seven games.

Lock in our Mercury vs. Fever prediction on PrizePicks before tip-off.

Mercury vs. Fever Picks, Player Stats for PrizePicks: 6/22/26

Here are the top Mercury vs. Fever picks to target on Monday, June 22. Tonight’s WNBA picks for PrizePicks include Natasha Mack and Sophie Cunningham.

Mercury F Natasha Mack vs. Fever: 8.5 Points

• Targeting Indiana’s interior defense is ideal, as it gives up 20.4 3-point shots per contest (the fewest) and 43.5 paint points per game (second-most).
• Natasha Mack has logged only 0.3 3-point attempts per game, taking most of her shots around the rim.
• She posts 9.5 PPG on the season and has reached 9 points in five of the past seven matchups, totaling 10.0 PPG during this span.
• Regular looks in the paint can lead to drawing fouls, and the Fever cede the most free throw attempts per game (26.0).
• Mack’s 11.7% offensive rebounding rate tops the Mercury by a landslide. Easy putbacks from the offensive glass is another angle for Mack stacking points on Monday night.

Add Natasha Mack to your PrizePicks Lineup now.

Fever G Sophie Cunningham vs. Mercury: 1.5 3-pointers Made

• As mentioned, Phoenix has a solid interior defense, but it has allowed the most 3-pointers per contest (9.6).
• That could mean success for Sophie Cunningham, who is third on the Fever with 4.3 3-point shots per game while shooting an elite 43.8% from deep.
• She’s on a roll over the last four games, proven by 15.0 PPG and a 63.3% field goal percentage in the split. 
• That success has led to increased volume from 3-point land, as Cunningham tallied 5.5 attempted triples per game during the four-game split.
• After converting 3.5 3-pointers per game over the previous four contests, Indiana’s sharpshooter could have another big night ahead.

Add Sophie Cunningham to your PrizePicks Lineup now.

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Make Mercury vs. Fever Picks on PrizePicks

The Mercury will likely look to slow the pace against a high-scoring Fever offense tonight. Led by a potential advantage in the tournament department, will Phoenix keep it close?

Don’t wait until tip-off — make your Mercury vs. Fever picks on PrizePicks now and earn real money if you’re right.

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