The Los Angeles Lakers are hitting their stride, seeking their 10th consecutive victory tonight. L.A. is listed as a 2.5-point favorite against the Detroit Pistons at 7:00 p.m. ET.
Los Angeles (46-25) won its ninth straight game on Saturday, edging Orlando 105-104. Detroit (51-19) rides a 6-1 hot stretch and holds a 7.5-game advantage over the Cleveland Cavaliers atop the Central Division.
Let’s look at the Lakers vs. Pistons prediction for Monday’s battle at Little Caesars Arena. Make your NBA picks on PrizePicks and PrizePicks Team Picks and earn real money if you’re right, including on game winners, spreads, and totals!
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Lakers vs. Pistons Prediction, Spread, Over/Under
Detroit has won three consecutive matchups with L.A., capped off by a 128-106 rout at Crypto.com Arena on December 30.
The Pistons shot 63% from the floor in that matchup, led by PG Cade Cunningham’s 27 points.
Lakers vs. Pistons Spread, Over/Under
The Lakers enter this matchup as 2.5-point favorites, returning a 1.66x payout on PrizePicks Team Picks if they win outright.
The Pistons are home underdogs with a 2.12x payout if they win, via PrizePicks Team Picks, where you can earn money with your picks in 35 states.
- Spread: Los Angeles Lakers -2.5
- Over/Under: 227.5
- Game Winner Payout: Lakers 1.66x | Pistons 2.12x
Team Picks data is live at the time of writing and is subject to change.
Lakers vs. Pistons Injury Report
Let’s dive into the full Lakers vs. Pistons injury report for Monday, via NBA.com.
Los Angeles Lakers Injury Report
- F Rui Hachimura (calf): Questionable
- C-PF Maxi Kleber (back): Questionable
- G Marcus Smart (ankle): Questionable
Detroit Pistons Injury Report
- PG Cade Cunningham (lung): OUT
- G Marcus Sasser (hip): OUT
- C Isaiah Stewart (calf): OUT
Lakers vs. Pistons Prediction on Spread – 3/23/26
Here are some key stats to know before locking in your Lakers vs. Pistons prediction on spread for Monday, March 23 on PrizePicks.
- The Lakers covered eight consecutive games before failing to cash as 2.5-point favorites in Saturday’s win over the Orlando Magic.
- Los Angeles owns a 9-4 record in its past 13 road contests, covering eight times.
- Cunningham remains sidelined with a collapsed lung, but the Pistons are 2-0 since he’s been out. They're 14-of-51 from 3-point range in that span.
- Since February 23, Detroit has compiled a 5-10 against-the-spread (ATS) mark.
- The Pistons failed to cover five of six home games before cashing as 5.5-point favorites in Friday’s 115-101 victory over the Golden State Warriors.
- The Lakers hit 29 3-pointers in victories over the Houston Rockets and Miami Heat but were held to 8-of-32 from downtown against the Magic.
- Los Angeles leads the league in field goal percentage at 49.9% and has eclipsed 50% shooting in four of the past six games.
Lakers vs. Pistons Picks for PrizePicks Today: 3/23/26
Here are three top Lakers vs. Pistons picks to target on Monday. Key PrizePicks player projections are headlined by PG Luka Doncic, SG Austin Reaves, and C Jalen Duren.
Lakers PG Luka Doncic vs. Pistons Projection: 32.5 Points
- Doncic leads the NBA in scoring at 33.4 points per game (PPG), a shade below his career high of 33.9 PPG in 2023-24 with Dallas.
- In Thursday’s 134-126 victory at Miami, Doncic dropped a season-high 60 points. It marked his 13th game of at least 40 points this year.
- Doncic has eclipsed 33 points in seven of the last nine games. He's attempted at least 24 shots in each of those outings and is shooting 48.9% from the floor.
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Pistons C Jalen Duren vs. Lakers Projection: 33.5 Pts + Rebs
- Duren posts 19.2 PPG and 10.5 rebounds per game, his third straight season averaging a double-double.
- In the last five games, the former University of Memphis standout is putting up 26.6 PPG, including a 36-point effort against the Washington Wizards on March 17.
- Duren pulled down at least 10 boards in five straight games before getting held to 6 against Golden State on Friday.
Lakers SG Austin Reaves vs. Pistons Projection: 21.5 Points
- Reaves is averaging a career-high 23.5 PPG and is coming off a 26-point effort against the Magic.
- He topped the 30-point mark in three consecutive home games before getting held to 18 or fewer points in three of the past four road outings.
- Reaves has struggled from downtown, converting on 5 of 26 attempts in the last five contests.
- AR has scored fewer than 20 points in nine of his past 10 road outings.
Make Lakers vs. Pistons Picks on PrizePicks
The Pistons look to slow down the streaking Lakers and pull off the season sweep of Los Angeles on Monday night. There’s never been a better time to add to the excitement of every NBA moment.
There is a wide variety of player stat projections on the PrizePicks NBA board, so you can build your Lineup however you’d like. Just pick at least two player stat projections and predict More or Less on them. Or, make your picks on winners, spreads, and over/unders on Team Picks, now available in 35 states.
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