The New York Knicks (37-21) will visit the Cleveland Cavaliers (36-22) in an Eastern Conference matchup on Tuesday. Both teams have enjoyed success lately, but the home team has been more impressive and is a threat to jump ahead of the visitors in the standings if they keep winning. Tip-off is set for 7:30 p.m. ET.
Below, we'll preview the game and drop our Knicks vs. Cavaliers prediction for PrizePicks for today, including for C-F Karl-Anthony Towns and G James Harden leading our player picks.
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Knicks vs. Cavaliers Prediction, Spread, Over/Under – 2/24/26
Two top-four teams in the Eastern Conference face off at Rocket Arena in this mid-week clash, and both teams have benefited from recent backcourt additions.
Cleveland sent G Darius Garland to the Clippers in a deal to acquire Harden ahead of this year’s trade deadline. It then went on a five-game winning streak following his Cavaliers debut before losing to the Oklahoma City Thunder. The Beard has helped breathe life into an offense that was already flourishing before his arrival.
The Cavs have the NBA’s third-ranked scoring offense and average 119.8 points per contest. That number has risen to 122.0 points per game since Harden’s first start with Cleveland. Harden’s ability to pass bigs into strong shot opportunities has a lot to do with that.
C Jarrett Allen’s scoring average has jumped from 13.9 to 20.7 with Harden in the fold, as his timely entry passes and lobs have made things easier for the big man. Getting easy points around the rim will likely be important against New York’s defense.
The Knicks, on the other hand, brought in G Jose Alvarado to cope while G Miles McBride deals with a core muscle injury. The Brooklyn native has provided New York with some much-needed bench support with his scoring and pesky ability to jump into passing lanes.
New York needs him to continue contributing off the pine at a high level, but Karl-Anthony Towns’ resurgence in a down shooting year will also be a major factor in this matchup. The big man is averaging the fewest points per game (20.1) he has since his rookie year, but appears to be on a roll in the back half of February.
Knicks vs. Cavaliers Over/Under, Spread
The Cavaliers are 4.5-point favorites, returning a 1.58x payout on PrizePicks Team Picks if they win outright.
The Knicks will return a 2.38x payout on PrizePicks Team Picks if they win outright.
- Spread: Cavaliers -4.5
- Over/Under: 231.5
- Gamer Winner Payout: Cavaliers 1.58x | Knicks 2.38x
(Team picks data is live as of publishing and is subject to change.)
Knicks vs. Cavaliers Injury Report
Let’s dive into the full Knicks vs. Cavaliers injury report for Monday, via NBA.com.
Knicks Injury Report
- G Miles McBride (core muscle surgery) – OUT
Cavaliers Injury Report
- F Max Strus (foot) – OUT
Knicks vs. Cavaliers Prediction on Spread
Here are some stats to know to help you make your Knicks vs. Cavaliers prediction against the spread today on PrizePicks Team Picks.
- The Cavaliers are 17-29 against the spread as favorites.
- The Knicks are 5-5 against the spread as underdogs.
- New York has covered the spread in five of its previous seven road games.
- The visitors give up the fourth-fewest assists per game (24.7).
- Only five teams give up fewer field goal attempts per game (86.8) than the Knicks.
Knicks vs. Cavaliers Picks, Stats for PrizePicks Today
Here are two of the top Knicks vs. Cavaliers picks on PrizePicks Player Picks for today. Player projections via the PrizePicks real money NBA game.
Cavaliers G James Harden vs. Knicks: 8 Assists
- Harden averages 8.7 assists per game with Cleveland.
- The Beard assists on 20.5 points per 75 possessions, according to databallr.
- The former Los Angeles Clipper boasts a career average of 9.0 assists per game against the Knicks.
- The 36-year-old has fallen short of 8 dimes just once in his previous 10 games.
Knicks C-F Karl-Anthony Towns vs. Cavaliers Projection: 19.5 Points
- KAT eclipsed 20 points in three straight games since the All-Star break.
- The Knicks’ big man is shooting a season-high 53.6% from the field in February.
- The Kentucky product posts 5.8 true shot attempts per 100 possessions, according to databallr.
- New York’s second-leading scorer has put up more shots (32) and points (53) than Brunson in his previous two outings.
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Make Knicks vs. Cavaliers NBA Picks on PrizePicks
The Cavaliers are one of the NBA’s hottest teams with James Harden, and they’ll battle a Knicks team that’s one game ahead of them in the Eastern Conference standings on Tuesday. Karl-Anthony Towns is coming on strong in the back half of the 2025-26 season and looks to stay hot.
You can make Cavaliers vs. Knicks picks on PrizePicks and PrizePicks Team Picks and earn real money. Just pick players, predict More or Less on their projected stats, and cash in if you’re correct. With Team Picks, make predictions on winners, spreads, and over/unders, now available in 34 states.
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