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Kansas vs. Houston Prediction on Spread for Friday, March 13

Kansas G Darryn Peterson dribbles the ball upcourt vs. Kansas State.
AP Photo/Reed Hoffmann

The second semifinal game of the Big 12 Tournament will pit the Kansas Jayhawks (23-9) vs. the Houston Cougars (27-5) in the T-Mobile Center.

This is the second meeting of the season between the two, and the Cougars will be looking to even the score after suffering a 69-56 loss vs. the Jayhawks in Phog Allen Fieldhouse in late February.

Houston is favored by 5.5 points for Friday's 9:30 p.m. ET tip-off, live on ESPN.

Who will have an advantage for tonight's Kansas vs. Houston prediction on the spread? Use PrizePicks Team Picks to make predictions on game winners, spreads, over/unders, and more.

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Kansas vs. Houston Prediction, Spread, Over/Under

It’s been a solid season for the Jayhawks, who sit at 12-6 in conference play. They boast three impressive wins vs. top-five opponents: No. 1 Arizona on February 9, No. 2 Iowa State on January 13, and No. 5 Houston on February 23. They also own some head-scratching losses vs. Cincinnati (18-15), West Virginia (18-14), and Arizona State (17-16).

At their best, this is an elite defensive team led by potential No. 1 2026 NBA Draft pick, G Darryn Peterson. The freshman phenom has played in only 21 games this season and averages just 28.4 minutes per game, but he's undeniably electric, leading the Jayhawks with 20.0 points per game.

Toughness and defense are staples of Houston head coach Kelvin Sampson-led teams, and this version of the Cougars epitomizes those characteristics. They are sixth in the country in adjusted defensive efficiency (93), according to Bart Torvik.

Offensively, they are led by Houston freshman G Kingston Flemings. He leads the Cougars in points (16.5) and assists (5.3) per game, and despite weighing 190 pounds soaking wet, he scores efficiently, shooting 48.3% from the field and 38.5% from deep.

Houston to win the Big 12 Tournament is currently returning a 3.03x payout on PrizePicks Team Picks.


Kansas vs. Houston Spread, Over/Under

The Cougars enter Friday’s game as 5.5-point favorites, returning a 1.38x payout if they win, per PrizePicks Team Picks.

The Jayhawks are the underdogs with a 2.7x payout to win outright, via PrizePicks Team Picks.

  • Spread: Houston Cougars -5.5
  • Over/Under: 137.5
  • Game Winner Payout: Kansas 2.94x | Houston 1.38x

Team Picks data is live at the time of writing and is subject to change.

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Kansas vs. Houston Prediction on Spread – 3/13/26

Here are the key stats to know before locking in your Kansas vs. Houston prediction on the spread for Friday, March 13, on PrizePicks.

  • Kansas is 20-12-0 (62.5%) against the spread (ATS) this season, tied for the best covering percentage in the Big 12.
  • Houston is just 15-17-0 (46.9%) ATS this season.
  • The Jayhawks covered and won outright as underdogs in their lone regular-season matchup vs. the Cougars.
  • It can be beneficial to take underdogs in low-total games, applying to this Big 12 battle.
  • With a total of just 134.5, scoring could be a rarity tonight, which could favor the 5.5-point underdog.
  • Despite Houston being known as one of CBB’s elite defensive programs, the Jayhawks have the better effective field goal percentage allowed at 45.1% — fourth-best in the country. The Cougars rank 20th at 46.9% allowed.
  • This game will take place in Kansas City and could serve as a de facto home game for the Jayhawks.

Make Kansas vs. Houston Picks on PrizePicks

Will Kansas go 2-0 against Houston this season, or will the Cougars enact revenge and continue their march to a Big 12 Championship?

You can make your Kansas vs. Houston picks on PrizePicks and PrizePicks Team Picks to earn real money. Just pick players, predict More or Less on their projected stats, and cash in if you’re correct. With Team Picks, make predictions on winners, spreads, and over/unders, now available in 35 states

Keep tabs on the Playbook for continued college basketball predictions, picks, and news.

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Team Picks and Culture Picks are event contracts offered by Performance Predictions II, LLC d/b/a PrizePicks Predict, a CFTC-registered FCM and NFA Member. All event contract customers must be U.S. residents and 18+. Some event contracts may not be available in every state. Event contract trading carries significant risk and is not appropriate for everyone. No guarantee against loss is offered. Past results are not necessarily indicative of future results. Void where prohibited by law. Restrictions apply. For full terms of service see prizepicks.com/predict-regulatory. Team and Culture Pick Early Payouts subject to market liquidity. The content provided is for informational and educational purposes only and does not constitute investment advice, or a recommendation to trade any commodity interest.

about the author

Adi Narang is a professional sports bettor and New York University graduate in Sports Management. A lifelong Denver sports fan, he’s spent over a decade applying data-driven analysis to trends, pricing, and game-level predictions. He’s always up for a sports conversation — from a Nikola Jokić GOAT debate to Korean Baseball batting orders.

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