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Houston vs. Iowa State Prediction, Spread, Monday College Basketball Picks

Iowa States Cyclones F Milan Momcilovic during a game against the TCU Horned Frogs.
AP Photo/Jessica Tobias

Two top dogs in the Big 12 collide on Monday night, as the Houston Cougars (23-2) travel to face the Iowa State Cyclones (22-3). ISU is third in the conference standings (9-3) and could carve into Houston’s (11-1) Big 12 lead with a win.

What could we expect from Monday’s prime-time 9:00 p.m. ET matchup on ESPN? The Cougars are on a six-game winning streak, while the Cyclones are 6-1 in the last seven matchups.

Let’s make a Houston vs. Iowa State prediction and Monday college basketball picks for this heavyweight clash, capped by player projections on PrizePicks.

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Houston vs. Iowa State Prediction, Spread, Over/Under

Since 2008, Iowa State is 4-2 in head-to-head matchups, but Houston is 2-1 in the last three collisions. The Cyclones have dominated against the spread (ATS), boasting a 5-0-1 record. The under is 4-1 in the past five meetings.

In a matchup between defensive-minded teams, the under is 7-3 in each squad’s last 10 games. The Cougs sport a 7-3 ATS mark over the previous 10 contests.

Houston vs. Iowa State Over/Under, Spread

In line with the defensive clash, Monday night’s bout features a low 134.5 total on PrizePicks Team Picks.

Houston is 5-1 on the road, but Iowa State boasts a perfect 14-0 home record. The Cyclones carry a home advantage, leading to a 1.63 payout to win on PrizePicks Team Picks.

  • Spread: Iowa State Cyclones -2.5
  • Over/Under: 134.5
  • Gamer Winner Payout: Houston 2.12x | Iowa State 1.63x

Team Picks data is live as of writing and is subject to change.

Houston vs. Iowa State Prediction on Spread

According to Bart Torvik, Houston is second in team efficiency, while Iowa State ranks eighth. Both squads feature elite defenses, with the Cougs ranked third in adjusted defensive efficiency and the Cyclones ninth.

Opponents record only 61.3 points per game against Houston (first), while ISU allows 64.5 PPG (sixth). Which offense may find the upper hand?

The Cougars are in the 81st and 60th percentiles for close-2 and 3-point shot distributions. Houston may be able to attack as it prefers — further proven by Iowa State allowing 23.4 attempted triples per game (45th percentile).

On the other end of the court, the Cyclones take only 22.8 shots from beyond the arc per game. They usually rely on getting to the rim, ranking in the 87th and 55th percentiles of dunk and close-2 shot distributions. The Cougars could have the answer by ceding a 32.3% close-2 shot distribution.

Additionally, EvanMiya gives Houston F Joseph Tugler (4.98) and F Chris Cenac Jr. (3.73) elite Defensive Bayesian Performance Ratings (DBPR).

Rounding out the Cougs’ potential advantage, they are in the 94th percentile of offensive rebounds per game. ISU ranks in the 66th percentile of defensive boards per matchup. 


Houston vs. Iowa State Picks for PrizePicks Today: Monday, February 16

Houston F Chris Cenac Jr. defines the Cougars’ ability to get to the rim and shoot triples. Plus, Iowa State F Milan Momcilovic could give the Cyclones an angle to score in player projections for PrizePicks.

Houston F Chris Cenac Jr. vs. Iowa State Projection: 9 Points

  • Cenac takes 68.2% of his shots from 2-point range, and his 6’11” frame and 7’4” wingspan should provide a height advantage for tonight. Momcilovic (6’8”) will likely be his primary defender, and his 2.53 DBPR ranks fourth in ISU’s starting lineup.
  • The freshman forward also shoots 37.1% from deep and has converted at least 2 triples in two of the last three games.
  • Iowa State ranks in the 21st and 27th percentiles of close-2 and 3-point shot distributions.
  • Cenac has posted 11.6 PPG in his last five games.

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Iowa State F Milan Momcilovic vs. Houston Projection: 17 Points

  • Houston sports an elite interior defense, but it surrenders a 42.8% 3-point shot distribution and 22.1 triple attempts per game. 
  • Momcilovic leads Iowa State with 7.5 3-point attempts per contest while shooting an electric 51.6% from deep.
  • EvanMiya credits the junior forward with a projected 3-point percentage of 42.4%, leading the nation.
  • Momcilovic averaged 20.9 PPG in his last eight games, shooting 47.9% from beyond the arc in the split.

Make Houston vs. Iowa State Picks on PrizePicks

Iowa State comes off an 18-point win over Kansas, while Houston has an average margin of +15.7 points during its six-game winning streak. Shot distributions could reveal which team to back for Monday night’s clash.

Make your Houston vs. Iowa State picks at PrizePicks, where you can earn real-money rewards for your predictions if you’re right. Just choose players, predict More or Less on their projected stats, and follow the hoops action to see if your picks hit. You can make picks on winners, spreads, and over/unders on Team Picks, now available in 34 states. 

Keep tabs on the Playbook for continued College Basketball predictions, picks, and news.

Get in the game! Sign up for PrizePicks and cash in on your sports predictions. Play $5 and get $50 instantly in Lineups with promo code PLAYBOOK.

Team Picks and Culture Picks are event contracts offered by Performance Predictions II, LLC d/b/a PrizePicks Predict, a CFTC-registered FCM and NFA Member. All event contract customers must be U.S. residents and 18+. Some event contracts may not be available in every state. Event contract trading carries significant risk and is not appropriate for everyone. No guarantee against loss is offered. Past results are not necessarily indicative of future results. Void where prohibited by law. Restrictions apply. For full terms of service see prizepicks.com/predict-regulatory. Team and Culture Pick Early Payouts subject to market liquidity. The content provided is for informational and educational purposes only and does not constitute investment advice, or a recommendation to trade any commodity interest.

about the author

Riley Thomas is a 2021 graduate of Ohio University who has worked for FanDuel Sportsbook and BetUS Sportsbook. He specializes in covering the NFL, NBA, college football, and college basketball. In Riley's free time, you can find him cheering on Ohio State and Kentucky or playing video games and reading the latest comics.

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