Georgia Southern vs. Old Dominion Prediction, Spread, NCAAF Picks – Thursday, October 15

Both the Georgia Southern Eagles and Old Dominion Monarchs enter tonight’s Sun Belt contest at 2-4. Kickoff is set for 7:30 p.m. ET on Thursday, October 15 at S.B. Ballard Stadium in Norfolk, Va. and will be televised nationally on ESPN2.

The Eagles split their first two conference contests and are coming off a 27-24 defeat to Sun Belt leader James Madison last Saturday. Georgia Southern covered as a 7.5-point underdog, marking its fifth cover in seven games.

Old Dominion snapped a four-game slide in a 10-3 triumph over Appalachian State as an 8.5-point underdog. The Monarchs lost only three games in 2025 and are looking to turn things around after a slow start.

Below, we'll break down our Georgia Southern vs. Old Dominion prediction and picks for Thursday's college football game, including the winner, spread, and over/under from PrizePicks.

Make your Georgia Southern vs. Old Dominion picks on PrizePicks now.

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Georgia Southern vs. Old Dominion Prediction, Spread, Over/Under – Thursday, October 15

The Eagles enter Thursday’s game as 3.5-point favorites against the Monarchs. Old Dominion returns a 2.32x payout if it wins outright, via PrizePicks Team Picks.

Here are the full payouts for the Georgia Southern vs. Old Dominion game on PrizePicks.

PrizePicks data is live at the time of writing and is subject to change.

Make your Georgia Southern vs. Old Dominion prediction on winner, over/under, and more on PrizePicks!

Old Dominion produced its best record last season since going 10-3 in 2016. However, after an opening-week victory over Norfolk State, the Monarchs dropped four straight, including a pair of 26+ point defeats to James Madison and Georgia State.

The Monarchs avoided an 0-3 Sun Belt start in an ugly 10-3 triumph at Appalachian State, which included a safety and a TD with a 2-point conversion. ODU ranks 138th nationally in offensive success rate according to Game on Paper, along with being 137th in EPA/pass and 128th in EPA/rush.

The Eagles have shown plenty of fight, losing by 15 points at Clemson and 14 to Houston, as well as suffering a narrow 3-point defeat to James Madison. The Dukes led 20-10 going into the fourth quarter, only for Georgia Southern to cut the deficit down twice but fail to hand JMU its first loss.

The only win over an FBS school for Georgia Southern came in its Sun Belt opener — a 31-24 victory over Coastal Carolina two weeks ago. Eagles QB Max Johnson threw 3 TD passes and has posted a trio of TD tosses in three consecutive games. One of his top PrizePicks projections for tonight is 1.5 Pass TDs.

Old Dominion has captured each of the past three matchups with Georgia Southern since 2023, capped off by a 45-10 rout at Statesboro last October. 

The Monarchs have experienced the most incredible offensive drop of any Sun Belt team from 2025. Last season, ODU averaged 457.5 yards per game but has slipped to dead last in the league, posting 266.0 YPG now.

The Monarchs are nearly 100 yards behind UL-Monroe while owning the second-worst adjusted EPA/play in the nation.

Georgia Southern vs. Old Dominion Prediction on Spread – 10/15/26

Here are the key game stats and trends behind our Georgia Southern vs. Old Dominion pick against the spread for Thursday, October 15.

• Georgia Southern owns a 13-4 against-the-spread (ATS) record since September 2025.
• The Eagles are 7-1 ATS as a favorite since the start of last season.
• Despite ODU’s offensive struggles, it's excelled at stopping the run, ranking 11th in defensive EPA/carry.
• ODU has allowed multiple TD passes in three of five games.
• The Monarchs have allowed one WR to compile at least 60 yards this season. Georgia Southern WR Josh Dallas is coming off a 111-yard effort against James Madison, his only game higher than 45 in 2026.
• Old Dominion’s cover against App State last week snapped a five-game ATS skid.
• The Monarchs ran 24 more plays than the Mountaineers but only gained 4.0 yards per play and compiled a total EPA figure of -23.57.

Lock in your Georgia Southern vs. Old Dominion prediction on PrizePicks.

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Make Georgia Southern vs. Old Dominion Picks on PrizePicks

The Monarchs have taken a major step backwards from last season. Can Old Dominion get back on track and continue its dominance of Georgia Southern, or will the Eagles break through in this important Sun Belt showdown?

Don’t wait until lock — make your Georgia Southern vs. Old Dominion picks on PrizePicks now and earn real money if you’re right.

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