FIU vs. Jacksonville State Prediction, Spread, NCAAF Picks for Tuesday, October 13

The Jacksonville State Gamecocks seek a 3-0 start in Conference USA play in a game vs. the FIU Panthers on Tuesday, October 13, at 7:30 p.m. ET on ESPNU. According to PrizePicks, Jacksonville State is a 2.5-point favorite for the spread tonight.

The Gamecocks held off Kennesaw State 27-26 last Wednesday to improve to 4-2. Jax State finished tied atop the league at 7-1 last season and seeks its 10th C-USA win in the past 11 tries.

FIU captured its league opener last week, pulling away from New Mexico State 22-3 as 6.5-point home favorites. The Panthers managed 5 field goals after scoring a first quarter TD, allowing just 3 points in each of the past two wins.

Below, we'll break down our FIU vs. Jacksonville State prediction and picks for Tuesday's college football game, including the winner, over/under, and key player picks for PrizePicks.

Make your FIU vs. Jacksonville State picks on PrizePicks now!

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FIU vs. Jacksonville State Prediction, Spread, Over/Under – Tuesday, October 13

The Gamecocks enter Tuesday’s game as 2.5-point favorites against the Panthers. FIU returns a 2.17x payout if they win outright, via PrizePicks.

Here are the full payouts for the FIU vs. Jacksonville State game. PrizePicks data is live at the time of writing and is subject to change.

Make your FIU vs. Jacksonville State prediction on the spread on PrizePicks!

Jacksonville State started this season on the wrong end of a 33-7 defeat at North Dakota State. The Gamecocks have won four of their past five games, with the only loss in this stretch coming by 2 points at Ohio on September 12.

FIU is not winning games because of its offense, but instead, due to a strong defense. The Panthers rank fourth nationally in defensive net EPA/play, according to Game on Paper, as well as ninth in EPA/pass and 11th in EPA/rush.

After allowing 57 points to UTSA in last season's First Responder Bowl, Florida International has given up only 61 points in the first five games of 2026.

In last week's last-minute triumph over Kennesaw State, the Gamecocks produced an 7.11 EPA, compared to 13.11 for the Owls. That was a significant difference from JSU's conference opening win over Middle Tennessee, as the Gamecocks posted an 18.31 EPA.

The Gamecocks joined Conference USA before the 2023 season and captured the first two matchups with the Panthers. FIU broke through last November in a 27-21 home victory, scoring the final 13 points after trailing 21-14 in the third quarter.

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FIU vs. Jacksonville State Prediction on the Spread – 10/13/26

Here are the key game stats and trends behind our FIU vs. Jacksonville State prediction on the spread for Tuesday, October 13.

• FIU owns a 3-1 against the spread (ATS) record against FBS opponents this season.
• The Gamecocks are 5-1 ATS as a favorite since last November.
• Both teams have struggled running the ball as the Panthers rank 138th in EPA/rush, while the Gamecocks sit 114th nationally out of 138 FBS schools.
• According to Prop Finder, its point spread model lists Jacksonville State as a 4.5-point favorite.
• FIU’s offensive success ranks 117th nationally but is fourth from a defensive success standpoint.
• Jacksonville State topped the 30-point mark five times in conference play in 2025 but has yet to reach 30 points in its first two league games.

Lock in your FIU vs. Jacksonville State prediction on PrizePicks before kickoff.

FIU vs. Jacksonville State Picks, Player Stats for PrizePicks – 10/13/26

Here are top FIU vs. Jacksonville State picks to target on PrizePicks for Tuesday, October 13. Today’s college football picks for PrizePicks include QB JJ Kohl and QB Caden Creel.

FIU QB JJ Kohl vs. Jacksonville State: 235.5 Pass Yards

• Kohl threw for at least 300 yards in each of the first two games against USF (301) and Buffalo (367).
• However, he has been held to less than 200 passing yards in the last two outings against LIU (135) and New Mexico State (115).
• The Gamecocks have allowed one QB to throw for more than 220 yards this season, yielding 293 yards to Kennesaw State’s Rickie Collins last week.
• Kohl’s EPA has slipped to -5.00 in each of the past two games against FBS foes FAU and New Mexico State. 

Add JJ Kohl to your PrizePicks lineup now.

Jacksonville State QB Caden Creel vs. FIU: 221.5 Pass Yards

• Creel topped the 300-yard mark twice, capped off by a 311-yard effort against Kennesaw State.
• He was limited to 198 passing yards in last season’s loss to FIU, posting his lowest completion percentage in conference play (56.7%).
• The Panthers haven’t allowed more than 202 passing yards to an opponent this season.
• Creel has performed well from an EPA standpoint in both C-USA contests, topping the 7.00 mark each time (7.12 vs. Kennesaw State and 8.05 vs. Middle Tennessee).  

Add Caden Creel to your PrizePicks lineup now.

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Make FIU vs. Jacksonville State Picks on PrizePicks

The Gamecocks have become the class of Conference USA since last season. Will Jacksonville State keep it up against a solid defensive squad in FIU tonight?

Don’t wait until lock — make your FIU vs. Jacksonville State picks on PrizePicks now and earn real money if you’re right.

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