For those who have been longing for afternoon baseball, there’ll be plenty of options on Sunday, March 29, including an AL West battle between the Los Angeles Angels and Houston Astros at 2:10 p.m. ET.
This will be the final bout of a four-game series, with the Angels looking to turn some heads with a 3-1 record to start the season.
Below, we’ll break down our Angels vs. Astros prediction and picks for Sunday’s matchup. Make your MLB picks on PrizePicks and earn real money if you’re right, including on game winners, spreads, and totals!
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Angels vs. Astros Prediction, Spread, Over/Under
The final game of the series is projected to have Angels SP Jack Kochanowicz (5.18 xFIP in 2025) and Astros SP Tatsuya Imai (2.26 xFIP in the NPB in 2025) on the bump. Imai is making his first MLB start, but he’s got a chance to have a breakout campaign in 2026 with Houston.
On Saturday, Los Angeles jumped out to a 6-0 lead in the top of the fifth inning, with homers from DH Jorge Soler and 2B Oswald Peraza early in the contest. However, the Angels were unable to generate much offense down the stretch, allowing the Astros to get back into the game.
Despite not hitting a home run, Houston scored 11 unanswered runs in Saturday's matchup, leading to its first win of the season. Los Angeles made a late surge, but it wasn’t enough to avoid its first loss of the year.
Angels vs. Astros Spread, Over/Under
The Angels enter Sunday’s game as road underdogs, returning a 2.43x payout on PrizePicks Team Picks if they win outright.
The Astros are home favorites with a 1.53x payout if they win, via PrizePicks Team Picks, where you can earn money with your picks in 35 states.
- Spread: Astros -1.5 (2.12x payout)
- Over/Under: 8.5 Runs (1.75x payout on over)
- Game Winner Payout: Angels 2.43x | Astros 1.56x
Team Picks data is live at the time of writing and is subject to change.
Angels vs. Astros Prediction to Win – 3/29/26
Here are the key stats to know before locking in your Angels vs. Astros prediction on the winner for Sunday, March 29, on PrizePicks.
- Across 111.0 IP in 2025, Jack Kochanowicz ranked in the third percentile in xERA (5.88), third percentile in xBA (.287), third percentile in strikeout rate (14.1%), and ninth percentile in walk rate (11.3%), per Baseball Savant.
- According to FanGraphs, Kochanowicz was worse on the road last season, logging a woeful 5.28 xFIP, 1.75 WHIP, and 2.37 HR/9 in that split. Comparatively, he had a 5.07 xFIP, 1.74 WHIP, and 1.00 HR/9 at home.
- Although spring training results aren’t always predictive of the regular season, Tatsuya Imai flashed upside with 7 strikeouts and only 2 hits allowed in 6.0 IP, per Baseball Reference.
- Last season, the Angels’ relievers tallied the fourth-worst xFIP (4.46) and second-worst HR/9 (1.41).
- While the Astros’ bullpen struggled with the long ball (1.26 HR/9 in 2025), they owned the 12th-best xFIP (4.08) and second-best xERA (3.58) a season ago.
- Houston’s bats got into a rhythm on Saturday, and Kochanowicz gave up 6 ER, 7 hits, and 3 walks in his lone start vs. the Astros in 2025.
Angels vs. Astros Picks for PrizePicks Today: 3/29/26
Here are the top Angels vs. Astros picks to target for Sunday, March 29, on PrizePicks. Today’s MLB picks for PrizePicks are headlined by Astros DH Yordan Alvarez and Astros SP Tatsuya Imai.
Astros DH Yordan Alvarez vs. Angels Projection: 7.5 Hitter Fantasy Score
- Kochanowicz coughed up a .393 wOBA, 5.04 xFIP, and 2.25 HR/9 to left-handed sluggers in 2025, compared to a .359 wOBA, 5.40 xFIP, and 0.84 HR/9 to right-handed sluggers, according to FanGraphs.
- With Yordan Alvarez seeing limited playing time due to injury in 2025, it’s worth noting he had a 156 wRC+, .386 wOBA, and .261 ISO when facing righties in 2024.
- Alvarez now has at least 1 extra-base hit in back-to-back games to begin the new season.
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Astros SP Tatsuya Imai vs. Angels Projection: 5 Strikeouts
- While it’s a different level of competition, Imai registered a solid 27.8% strikeout rate and 0.89 WHIP across 163.2 IP in the Nippon Professional Baseball league last year.
- Just last season, the Angels recorded the fifth-worst wRC+ (92) and highest strikeout rate (27.1%) vs. right-handed hurlers.
- Los Angeles has struck out at least 11 times in two of its st three games this season.
Make Angels vs. Astros Picks on PrizePicks
The Astros were able to avoid a series sweep to begin the year, and they’ll be looking to keep it rolling after their first win of the 2026 campaign. Will the Angels be able to overcome having a potential disadvantage on the bump in Sunday’s divisional showdown?
You can make your Angels vs. Astros picks on PrizePicks and PrizePicks Team Picks to earn real money. Just pick players, predict More or Less on their projected stats, and cash in if you’re correct. With Team Picks, make predictions on winners, spreads, and over/unders, now available in 35 states.
Stick around with the Playbook for continued MLB predictions, picks, and news throughout the 2026 season.
