Two Italian giants clash on Sunday, April 26, when AC Milan hosts Juventus at 2:45 p.m. ET on Paramount+ from the San Siro.
Juventus are slightly favored to pick up all three points on the road, returning a 2.50x payout if they win, according to PrizePicks Team Picks.
Milan’s minuscule title hopes could be officially gone before kickoff should Inter Milan win earlier in the day, but both Milan and Juventus still need points to secure their spot in Champions League next season.
The Rossoneri have lost three of their last five, while the Old Lady are enjoying an eight-match unbeaten run.
Below, we’ll break down our AC Milan vs. Juventus prediction and picks for Sunday afternoon’s Serie A match, including the spread, total goals, and key player picks for PrizePicks.
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AC Milan vs. Juventus Prediction, Picks for Serie A – Sunday, April 26
AC Milan enter Sunday sitting 12 points adrift of Inter Milan, who could clinch the Scudetto with a victory and a Milan draw or defeat.
That said, Milan’s focus at this point must be on maintaining a grasp on a top four spot. Fifth-placed Roma closed the gap on Saturday to just five points, and sixth-placed Como would join them should they win on Sunday morning.
Juventus sits in fourth, just two points clear of Roma, so victory here is vital. The Old Lady is in fine form, taking 17 of a possible 21 points over their last seven matches. Their defense has been rock solid during this run, conceding just 1 goal in their last six matches.
Milan will be at full strength on Sunday, a rarity for this time of the season. Juventus will be without LB Juan Cabal and ST Arkadiusz Milik but have plenty of depth to deal with their absences.
Both FW Christian Pulisic and FW Rafael Leao are expected to start for the Rossoneri, but neither has scored in the last six matches. In fact, Milan have scored just once in their last three outings, and their 5 goals over their last six matches have all come from either CMs or defenders.
Milan and Juventus have both kept 14 clean sheets this season, ranking fifth in Serie A. Juventus has allowed just 91 shots on target this season, the fewest in the competition, while Milan GKs have the highest save percentage in the league.
Both teams need at least a point here, and that could play into the mindset of each side. It may take a moment of individual brilliance to break down two of the best defenses in Serie A if either side is to come out on top.
AC Milan vs. Juventus Spread, Total Goals, Payouts – Sunday, April 26
Juventus enters Sunday’s match as road favorites, returning a 2.50x payout if they win outright, via PrizePicks Team Picks.
Here are the full payouts for the AC Milan vs. Juventus match on PrizePicks.
- Winner Payout: AC Milan – 2.63x | Tie – 2.94x | Juventus – 2.50x
- Spread: Juventus -1.5 (5.26x Payout)
- Total Goals: 2.5 (Over – 2x)
- Both Teams to Score: Yes 1.72x | No 2.04x
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Team Picks data is live at the time of writing and is subject to change.
AC Milan vs. Juventus Prediction on Total Goals – 4/26/26
Here are the key stats and trends behind our AC Milan vs. Juventus prediction on total goals for Sunday, April 26.
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- Two or fewer goals have been scored in the last nine Serie A matches between these sides.
- Three of the last four Serie A clashes between Milan and Juventus have ended in goalless draws.
- There have been fewer than 3 goals in nine of the last 11 meetings between these sides at the San Siro.
- No more than 2 goals have been scored in each of Juventus’ last five Serie A matches.
- AC Milan have not scored against Juventus in any of their last five Serie A fixtures.
- At least one side has failed to score in eight consecutive Serie A meetings between the clubs.
- Milan have conceded just 27 goals in 33 matches, the fewest of any club in Serie A this season.
- Milan GK Mike Maignan’s 76.7% save percentage ranks fourth among all Serie A keepers, per Fotmob.
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AC Milan vs. Juventus Projected Lineups for Sunday, April 26
Here are the projected AC Milan vs. Juventus lineups for today's Serie A match. Lineups are not official.
AC Milan Lineup vs. Juventus: Projected 3-5-2
- Goalkeeper: Mike Maignan
- Defense: Fikayo Tomori, Matteo Gabbia, Strahinja Pavlovic
- Midfield: Alexis Saelemaekers, Wesley Fofana, Adrian Rabiot, Luka Modric, Davide Bartesaghi
- Forwards: Rafael Leao, Christian Pulisic
Juventus Lineup vs. AC Milan: Projected 3-4-3
- Goalkeeper: Michele Di Gregorio
- Defense: Pierre Kalulu, Bremer, Lloyd Kelly
- Midfield: Weston McKennie, Manuel Locatelli, Khephren Thuram-Ulien, Andrea Cambiaso
- Forwards: Francisco Conceicao, Jonathan David, Kenan Yildiz
AC Milan vs. Juventus Player Picks, Stats for PrizePicks – 4/26/26
Here are three AC Milan vs. Juventus picks to target on players for Sunday, April 26. Today’s Serie A picks for PrizePicks are headlined by Christian Pulisic and Luka Modric.
Milan FW Christian Pulisic vs. Juventus Projection: 28.5 Passes Attempted
- Christian Pulisic has averaged 46.21 passes per 90 minutes over his last five matches.
- In his last two starts, the American has attempted exactly 40 passes.
- Pulisic has 35 passes or more in each of his last four starts.
- The Milan attacker attempted 31 passes in 74 minutes in the reverse fixture on October 5, 2025.
- AC Milan held 49% possession in the reverse fixture in Turin, as they attempted 472 passes on the day.
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Milan MF Luka Modric vs. Juventus Projection: 68.5 Passes Attempted
- Luka Modric attempted 76 passes in 90 minutes in the reverse fixture.
- The Croatian midfielder has attempted at least 64 passes in eight of his last nine starts for Milan.
- He’s also attempted at least 70 passes in four of his last five starts.
- Modric has played a full 90 minutes in 26 of his 31 Serie A starts for Milan this season.
- Milan’s midfield metronome averages 71.2 passes per 90 minutes in league play this year.
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Juventus GK Michele Di Gregorio vs. Milan Projection: 3 Goalie Saves
- Milan have put just 18 shots on target over their last six matches, despite attempting 74 shots.
- The Rossoneri have scored on 5 of those 18 shots on target.
- Juventus GK Michele Di Gregorio averages 2.1 saves per 90 minutes this season.
- The Old Lady have allowed opponents to average just 2.76 shots on target per match, the fewest of any Serie A club.
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Both Milan and Juventus come into Sunday knowing points are at a premium with just five matches remaining, as the ever-important Champions League positions still hang in the balance. As such, this could be an extremely cagey affair that may be decided by one or two moments of brilliance, either at the offensive or defensive end of the pitch.
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Stay locked in on Playbook for more Serie A predictions and expert picks through the end of the season.
