The Clemson Tigers (20-4, 10-1 ACC) look to pull into a first-place tie with Duke atop the conference before their showdown on Saturday.
Clemson returns home after sweeping a pair of games in the Bay Area against Stanford (66-64) and California (77-55).
The Virginia Tech Hokies (16-8, 5-6 ACC) try to snap a two-game slide after losses to Duke (72-58) and North Carolina State (82-73).
Let’s look at the Virginia Tech vs. Clemson spread prediction for Wednesday’s battle at Littlejohn Coliseum, tipping off at 7:00 p.m. ET on ACC Network.
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Virginia Tech vs. Clemson Prediction, Spread
Clemson cruised to a pair of blowout wins over Virginia Tech last season. The Tigers topped the Hokies in Blacksburg, 72-57 as 8.5-point favorites on January 25, 2025.
In Virginia Tech’s last visit to Clemson on March 8, 2025, the Hokies were run out by the Tigers, 65-47. Clemson grabbed another cover as 17-point favorites, improving to 4-1 in the past five matchups with Virginia Tech.
Virginia Tech vs. Clemson Over/Under, Spread
The Tigers enter this matchup as 9.5-point favorites, returning a 1.17x payout on PrizePicks Team Picks if they win outright.
The Hokies are road underdogs with a 4.54x payout if they win, via PrizePicks Team Picks.
- Spread: Clemson -9.5
- Over/Under: 136.5
- Game Winner Payout: Virginia Tech 4.54x | Clemson 1.17x
(Team Picks data is live as of writing and is subject to change)
Virginia Tech vs. Clemson Numbers to Know
Here are some facts and figures to get you set for Virginia Tech vs. Clemson tonight, including insights on our Virginia Tech vs. Clemson prediction.
- The Tigers are 9-2 against the spread (ATS) in conference play. One of the non-covers came at Stanford as 3.5-point favorites, thanks to the Cardinal scoring a meaningless layup as time expired to lose by two.
- Clemson has covered the number in four of the last five home games, including three straight double-digit victories.
- Since December 2, the Hokies have posted an incredible 7-1 ATS mark in the underdog role.
- Virginia Tech is 6-0 ATS in the last six opportunities away from Blacksburg.
- The Hokies allowed N.C. State to shoot 42.9% from 3-point range, but Virginia Tech has not given up at least 40% shooting from deep in consecutive games.
- In four of the last seven games, Clemson knocked down more than 40% of its 3-point attempts.
- Clemson runs the slowest tempo among any ACC team in conference play, resulting in six unders the last seven games.
- The Hokies posted a 4-0 under streak prior to barely hitting the over of 153.5 against N.C. State.
- Five of Clemson’s ten conference victories are against teams at 2-8 or worse.
- Four of Virginia Tech’s six ACC losses came to teams ahead of them in the league.
Virginia Tech vs. Clemson CBB Player Picks
Here are three top Virginia Tech vs. Clemson picks to target on Wednesday. Key PrizePicks player projections are headlined by three players: Clemson F RJ Godfrey, Virginia Tech F Amani Hansberry, and Tigers G Jestin Porter.
Clemson F RJ Godfrey vs. Virginia Tech Projection: 12.5 Points
- Godfrey averages a career-high 11.9 points per game (PPG), which is also tops on the Tigers.
- The senior finished with 10 or less points in five of the last seven games.
- In three of the past five outings, Godfrey shot at least 75% from the floor. The Hokies rank 12th in ACC play in defensive 2-point percentage (54.7%).
- He has failed to pass this projection in six of the previous eight games at Littlejohn Coliseum.
Virginia Tech F Amani Hansberry vs. Clemson Projection: 19.5 Pts+Rebs
- The junior averages a team-high 15.2 PPG and ranks second with 8.2 rebounds per contest.
- He has compiled at least 20 points and rebounds in consecutive games against Duke and N.C. State.
- The Maryland native pulled down double-digit boards in four straight games from late December to early January. He has not racked up at least 10 rebounds in eight consecutive contests.
- In last four road games, Hansberry averages 11.7 PPG and 6.5 RPG and failed to reach this projection three times.
Clemson G Jestin Porter vs. Virginia Tech Projection: 9.5 Points
- Porter averaged 15.0 PPG at Middle Tennessee last season, but dropped to 10.5 PPG in his first season at Clemson.
- In the last five outings, the senior hasn’t reached double-digit scoring. He shot 12-of-44 (27%) from the floor and averaged 7.4 PPG.
- Since posting a season-high 26 points against Notre Dame on January 10, Porter has scored in double-digits once in the last seven games.
- In the past seven games, the Houston native converted 3 free throws. The Hokies own the third-lowest defensive free-throw rate in conference play.
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Make Virginia Tech vs. Clemson Picks on CBB on PrizePicks
Clemson is on the verge of a first-place tie in the conference with Duke, but Virginia Tech seeks another cover as a road underdog.
There’s never been a better time to add to the excitement of every CBB moment than with PrizePicks.
There are hundreds of player stat projections on the CBB board for every game; just pick at least two player stat projections to build your Lineup on PrizePicks. Or, make your picks on winners, spreads, and over/unders on Team Picks, now available in 34 states!
Check out the Playbook throughout the season for more CBB picks, predictions, and news every day.
